{
    "info": {
        "nct_id": "NCT01768195",
        "official_title": "Prophylactic Use of Entecavir for HBsAg Positive Lymphoma Patients Treated With Rituximab-based Immunochemotherapy",
        "inclusion_criteria": "* treatment-naive patients with B-cell lymphoma\n* HBsAg positive at baseline\n* treated with rituximab-based immunochemotherapy\n* life expectancy of more than 3 months\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* younger than 18 years old\n* HBsAg negative at baseline\n* pregnant or lactating women",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* treatment-naive patients with B-cell lymphoma",
                "criterions": [
                    {
                        "exact_snippets": [
                            "treatment-naive"
                        ],
                        "criterion": "treatment status",
                        "requirement_type": "status",
                        "expected_value": "naive"
                    },
                    {
                        "exact_snippets": [
                            "B-cell lymphoma"
                        ],
                        "criterion": "B-cell lymphoma",
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "treatment-naive"
                        ],
                        "criterion": "treatment status",
                        "requirement_type": "status",
                        "expected_value": "naive"
                    },
                    {
                        "exact_snippets": [
                            "B-cell lymphoma"
                        ],
                        "criterion": "B-cell lymphoma",
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* HBsAg positive at baseline",
                "criterions": [
                    {
                        "exact_snippets": [
                            "HBsAg positive"
                        ],
                        "criterion": "HBsAg",
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "HBsAg positive"
                        ],
                        "criterion": "HBsAg",
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* treated with rituximab-based immunochemotherapy",
                "criterions": [
                    {
                        "exact_snippets": [
                            "treated with rituximab-based immunochemotherapy"
                        ],
                        "criterion": "rituximab-based immunochemotherapy",
                        "requirement_type": "treatment",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "treated with rituximab-based immunochemotherapy"
                        ],
                        "criterion": "rituximab-based immunochemotherapy",
                        "requirement_type": "treatment",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* life expectancy of more than 3 months",
                "criterions": [
                    {
                        "exact_snippets": [
                            "life expectancy",
                            "more than 3 months"
                        ],
                        "criterion": "life expectancy",
                        "requirement_type": "duration",
                        "expected_value": {
                            "operator": ">",
                            "value": 3
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "life expectancy",
                            "more than 3 months"
                        ],
                        "criterion": "life expectancy",
                        "requirement_type": "duration",
                        "expected_value": {
                            "operator": ">",
                            "value": 3
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Healthy volunteers allowed"
                        ],
                        "criterion": "healthy volunteers",
                        "requirement_type": "participation",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Healthy volunteers allowed"
                        ],
                        "criterion": "healthy volunteers",
                        "requirement_type": "participation",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": [
                            "minimum age of 18 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "minimum",
                        "expected_value": {
                            "operator": ">=",
                            "value": 18
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "minimum age of 18 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "minimum",
                        "expected_value": {
                            "operator": ">=",
                            "value": 18
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* younger than 18 years old",
                "criterions": [
                    {
                        "exact_snippets": [
                            "younger than 18 years old"
                        ],
                        "criterion": "age",
                        "requirement_type": "range",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": "<",
                                    "value": 18
                                }
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "younger than 18 years old"
                    ],
                    "criterion": "age",
                    "requirement_type": "range",
                    "expected_value": {
                        "comparisons": [
                            {
                                "operator": "<",
                                "value": 18
                            }
                        ]
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* HBsAg negative at baseline",
                "criterions": [
                    {
                        "exact_snippets": [
                            "HBsAg negative"
                        ],
                        "criterion": "HBsAg",
                        "requirement_type": "presence",
                        "expected_value": false
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "HBsAg negative"
                    ],
                    "criterion": "HBsAg",
                    "requirement_type": "presence",
                    "expected_value": false
                }
            }
        },
        {
            "identified_line": {
                "line": "* pregnant or lactating women",
                "criterions": [
                    {
                        "exact_snippets": [
                            "pregnant"
                        ],
                        "criterion": "pregnancy",
                        "requirement_type": "status",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "lactating"
                        ],
                        "criterion": "lactation",
                        "requirement_type": "status",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": [
                            "pregnant"
                        ],
                        "criterion": "pregnancy",
                        "requirement_type": "status",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "lactating"
                        ],
                        "criterion": "lactation",
                        "requirement_type": "status",
                        "expected_value": true
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}