{
    "info": {
        "nct_id": "NCT01765231",
        "official_title": "Prophylactic Use of Entecavir for HBsAg Negative/HBcAb Positive/Hepatitis B Virus DNA Negative Patients With Lymphoma",
        "inclusion_criteria": "* treatment-naive patients with lymphoma\n* HBsAg negative/HBcAb positive/hepatitis B virus DNA negative at baseline\n* treated with chemotherapy and/or immunosuppressive therapy\n* life expectancy of more than 3 months\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* younger than 18 years old\n* HBsAg positive or HBcAb negative or hepatitis B virus DNA positive at baseline\n* pregnant or lactating women",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* treatment-naive patients with lymphoma",
                "criterions": [
                    {
                        "exact_snippets": [
                            "treatment-naive"
                        ],
                        "criterion": "treatment status",
                        "requirement_type": "status",
                        "expected_value": "naive"
                    },
                    {
                        "exact_snippets": [
                            "lymphoma"
                        ],
                        "criterion": "lymphoma",
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "treatment-naive"
                        ],
                        "criterion": "treatment status",
                        "requirement_type": "status",
                        "expected_value": "naive"
                    },
                    {
                        "exact_snippets": [
                            "lymphoma"
                        ],
                        "criterion": "lymphoma",
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* HBsAg negative/HBcAb positive/hepatitis B virus DNA negative at baseline",
                "criterions": [
                    {
                        "exact_snippets": [
                            "HBsAg negative"
                        ],
                        "criterion": "HBsAg",
                        "requirement_type": "presence",
                        "expected_value": false
                    },
                    {
                        "exact_snippets": [
                            "HBcAb positive"
                        ],
                        "criterion": "HBcAb",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "hepatitis B virus DNA negative"
                        ],
                        "criterion": "hepatitis B virus DNA",
                        "requirement_type": "presence",
                        "expected_value": false
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "HBsAg negative"
                        ],
                        "criterion": "HBsAg",
                        "requirement_type": "presence",
                        "expected_value": false
                    },
                    {
                        "exact_snippets": [
                            "HBcAb positive"
                        ],
                        "criterion": "HBcAb",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "hepatitis B virus DNA negative"
                        ],
                        "criterion": "hepatitis B virus DNA",
                        "requirement_type": "presence",
                        "expected_value": false
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* treated with chemotherapy and/or immunosuppressive therapy",
                "criterions": [
                    {
                        "exact_snippets": [
                            "treated with chemotherapy"
                        ],
                        "criterion": "chemotherapy",
                        "requirement_type": "treatment",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "treated with",
                            "immunosuppressive therapy"
                        ],
                        "criterion": "immunosuppressive therapy",
                        "requirement_type": "treatment",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": [
                                    "treated with chemotherapy"
                                ],
                                "criterion": "chemotherapy",
                                "requirement_type": "treatment",
                                "expected_value": true
                            },
                            {
                                "exact_snippets": [
                                    "treated with",
                                    "immunosuppressive therapy"
                                ],
                                "criterion": "immunosuppressive therapy",
                                "requirement_type": "treatment",
                                "expected_value": true
                            }
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* life expectancy of more than 3 months",
                "criterions": [
                    {
                        "exact_snippets": [
                            "life expectancy of more than 3 months"
                        ],
                        "criterion": "life expectancy",
                        "requirement_type": "duration",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": ">",
                                    "value": 3
                                }
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "life expectancy of more than 3 months"
                        ],
                        "criterion": "life expectancy",
                        "requirement_type": "duration",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": ">",
                                    "value": 3
                                }
                            ]
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Healthy volunteers allowed"
                        ],
                        "criterion": "volunteer health status",
                        "requirement_type": "allowance",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Healthy volunteers allowed"
                        ],
                        "criterion": "volunteer health status",
                        "requirement_type": "allowance",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": [
                            "minimum age of 18 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "minimum",
                        "expected_value": {
                            "operator": ">=",
                            "value": 18
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "minimum age of 18 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "minimum",
                        "expected_value": {
                            "operator": ">=",
                            "value": 18
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* younger than 18 years old",
                "criterions": [
                    {
                        "exact_snippets": [
                            "younger than 18 years old"
                        ],
                        "criterion": "age",
                        "requirement_type": "range",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": "<",
                                    "value": 18
                                }
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "younger than 18 years old"
                    ],
                    "criterion": "age",
                    "requirement_type": "range",
                    "expected_value": {
                        "comparisons": [
                            {
                                "operator": "<",
                                "value": 18
                            }
                        ]
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* HBsAg positive or HBcAb negative or hepatitis B virus DNA positive at baseline",
                "criterions": [
                    {
                        "exact_snippets": [
                            "HBsAg positive"
                        ],
                        "criterion": "HBsAg",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "HBcAb negative"
                        ],
                        "criterion": "HBcAb",
                        "requirement_type": "presence",
                        "expected_value": false
                    },
                    {
                        "exact_snippets": [
                            "hepatitis B virus DNA positive"
                        ],
                        "criterion": "hepatitis B virus DNA",
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": [
                            "HBsAg positive"
                        ],
                        "criterion": "HBsAg",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "HBcAb negative"
                        ],
                        "criterion": "HBcAb",
                        "requirement_type": "presence",
                        "expected_value": false
                    },
                    {
                        "exact_snippets": [
                            "hepatitis B virus DNA positive"
                        ],
                        "criterion": "hepatitis B virus DNA",
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* pregnant or lactating women",
                "criterions": [
                    {
                        "exact_snippets": [
                            "pregnant"
                        ],
                        "criterion": "pregnancy",
                        "requirement_type": "status",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "lactating"
                        ],
                        "criterion": "lactation",
                        "requirement_type": "status",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": [
                            "pregnant"
                        ],
                        "criterion": "pregnancy",
                        "requirement_type": "status",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "lactating"
                        ],
                        "criterion": "lactation",
                        "requirement_type": "status",
                        "expected_value": true
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}