{
    "info": {
        "nct_id": "NCT01642875",
        "official_title": "Early Oral Versus Enteral Nutrition After Pancreatoduodenectomy for Periampullary Tumors: a Prospective, Randomized, Controlled Clinical Trial",
        "inclusion_criteria": "* Primary periampullary tumor\n* R0, R1 resection\n* Chronic pancreatitis requiring pancreatoduodenectomy\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Metastatic tumor\n* Locally unresectable tumor\n* Previous gastric resection\n* ASA IV-V\n* Age under 18 years\n* Preoperative complete parenteral or enteral feeding\n* Immunosuppressive therapy before operation\n* Severe malnutrition\n* Lack of the patient's consent for the trial participation, feeding tube insertion or epidural analgesia",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* Primary periampullary tumor",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Primary periampullary tumor"
                        ],
                        "criterion": "periampullary tumor",
                        "requirement_type": "primary",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Primary periampullary tumor"
                        ],
                        "criterion": "periampullary tumor",
                        "requirement_type": "primary",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* R0, R1 resection",
                "criterions": [
                    {
                        "exact_snippets": [
                            "R0, R1 resection"
                        ],
                        "criterion": "resection",
                        "requirement_type": "type",
                        "expected_value": [
                            "R0",
                            "R1"
                        ]
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "R0, R1 resection"
                        ],
                        "criterion": "resection",
                        "requirement_type": "type",
                        "expected_value": [
                            "R0",
                            "R1"
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Chronic pancreatitis requiring pancreatoduodenectomy",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Chronic pancreatitis"
                        ],
                        "criterion": "chronic pancreatitis",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "requiring pancreatoduodenectomy"
                        ],
                        "criterion": "pancreatoduodenectomy",
                        "requirement_type": "necessity",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Chronic pancreatitis"
                        ],
                        "criterion": "chronic pancreatitis",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "requiring pancreatoduodenectomy"
                        ],
                        "criterion": "pancreatoduodenectomy",
                        "requirement_type": "necessity",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Healthy volunteers allowed"
                        ],
                        "criterion": "healthy volunteers",
                        "requirement_type": "participation",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Healthy volunteers allowed"
                        ],
                        "criterion": "healthy volunteers",
                        "requirement_type": "participation",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": [
                            "minimum age of 18 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "minimum",
                        "expected_value": {
                            "operator": ">=",
                            "value": 18
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "minimum age of 18 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "minimum",
                        "expected_value": {
                            "operator": ">=",
                            "value": 18
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* Metastatic tumor",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Metastatic tumor"
                        ],
                        "criterion": "tumor",
                        "requirement_type": "metastasis",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "Metastatic tumor"
                    ],
                    "criterion": "tumor",
                    "requirement_type": "metastasis",
                    "expected_value": true
                }
            }
        },
        {
            "identified_line": {
                "line": "* Locally unresectable tumor",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Locally unresectable tumor"
                        ],
                        "criterion": "tumor",
                        "requirement_type": "resectability",
                        "expected_value": "locally unresectable"
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "Locally unresectable tumor"
                    ],
                    "criterion": "tumor",
                    "requirement_type": "resectability",
                    "expected_value": "locally unresectable"
                }
            }
        },
        {
            "identified_line": {
                "line": "* Previous gastric resection",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Previous gastric resection"
                        ],
                        "criterion": "gastric resection",
                        "requirement_type": "history",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "Previous gastric resection"
                    ],
                    "criterion": "gastric resection",
                    "requirement_type": "history",
                    "expected_value": true
                }
            }
        },
        {
            "identified_line": {
                "line": "* ASA IV-V",
                "criterions": [
                    {
                        "exact_snippets": [
                            "ASA IV-V"
                        ],
                        "criterion": "ASA classification",
                        "requirement_type": "range",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": ">=",
                                    "value": 4
                                },
                                {
                                    "operator": "<=",
                                    "value": 5
                                }
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "ASA IV-V"
                    ],
                    "criterion": "ASA classification",
                    "requirement_type": "range",
                    "expected_value": {
                        "comparisons": [
                            {
                                "operator": ">=",
                                "value": 4
                            },
                            {
                                "operator": "<=",
                                "value": 5
                            }
                        ]
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Age under 18 years",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Age under 18 years"
                        ],
                        "criterion": "age",
                        "requirement_type": "range",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": "<",
                                    "value": 18
                                }
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "Age under 18 years"
                    ],
                    "criterion": "age",
                    "requirement_type": "range",
                    "expected_value": {
                        "comparisons": [
                            {
                                "operator": "<",
                                "value": 18
                            }
                        ]
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Preoperative complete parenteral or enteral feeding",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Preoperative complete parenteral or enteral feeding"
                        ],
                        "criterion": "parenteral feeding",
                        "requirement_type": "preoperative",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "Preoperative complete parenteral or enteral feeding"
                        ],
                        "criterion": "enteral feeding",
                        "requirement_type": "preoperative",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": [
                            "Preoperative complete parenteral or enteral feeding"
                        ],
                        "criterion": "parenteral feeding",
                        "requirement_type": "preoperative",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "Preoperative complete parenteral or enteral feeding"
                        ],
                        "criterion": "enteral feeding",
                        "requirement_type": "preoperative",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Immunosuppressive therapy before operation",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Immunosuppressive therapy before operation"
                        ],
                        "criterion": "immunosuppressive therapy",
                        "requirement_type": "timing",
                        "expected_value": "before operation"
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "Immunosuppressive therapy before operation"
                    ],
                    "criterion": "immunosuppressive therapy",
                    "requirement_type": "timing",
                    "expected_value": "before operation"
                }
            }
        },
        {
            "identified_line": {
                "line": "* Severe malnutrition",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Severe malnutrition"
                        ],
                        "criterion": "malnutrition",
                        "requirement_type": "severity",
                        "expected_value": "severe"
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "Severe malnutrition"
                    ],
                    "criterion": "malnutrition",
                    "requirement_type": "severity",
                    "expected_value": "severe"
                }
            }
        },
        {
            "identified_line": {
                "line": "* Lack of the patient's consent for the trial participation, feeding tube insertion or epidural analgesia",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Lack of the patient's consent for the trial participation"
                        ],
                        "criterion": "patient's consent",
                        "requirement_type": "presence",
                        "expected_value": false
                    },
                    {
                        "exact_snippets": [
                            "Lack of the patient's consent for",
                            "feeding tube insertion"
                        ],
                        "criterion": "patient's consent for feeding tube insertion",
                        "requirement_type": "presence",
                        "expected_value": false
                    },
                    {
                        "exact_snippets": [
                            "Lack of the patient's consent for",
                            "epidural analgesia"
                        ],
                        "criterion": "patient's consent for epidural analgesia",
                        "requirement_type": "presence",
                        "expected_value": false
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": [
                                    "Lack of the patient's consent for the trial participation"
                                ],
                                "criterion": "patient's consent",
                                "requirement_type": "presence",
                                "expected_value": false
                            }
                        ]
                    },
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": [
                                    "Lack of the patient's consent for",
                                    "feeding tube insertion"
                                ],
                                "criterion": "patient's consent for feeding tube insertion",
                                "requirement_type": "presence",
                                "expected_value": false
                            }
                        ]
                    },
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": [
                                    "Lack of the patient's consent for",
                                    "epidural analgesia"
                                ],
                                "criterion": "patient's consent for epidural analgesia",
                                "requirement_type": "presence",
                                "expected_value": false
                            }
                        ]
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}