{
    "info": {
        "nct_id": "NCT02816164",
        "official_title": "A Multi Centre Study to Compare Administration Schedules of G-CSF (Filgrastim) for Primary Prophylaxis of Chemotherapy-Induced Febrile Neutropenia in Early Stage Breast Cancer (REaCT-G2)",
        "inclusion_criteria": "* Histologically confirmed primary breast cancer\n* Planned to start docetaxel component of FEC-D or AC-D, or first cycle of; dose-dense AC-T, TC, FEC-D or TAC chemotherapy\n* ≥19 years of age\n* Able to provide verbal consent\nHealthy volunteers allowed\nMust have minimum age of 19 Years",
        "exclusion_criteria": "* Contraindication to Filgrastim",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Histologically confirmed primary breast cancer",
            "criterions": [
                {
                    "exact_snippets": [
                        "Histologically confirmed"
                    ],
                    "criterion": "breast cancer",
                    "requirement_type": "confirmation method",
                    "expected_value": "histological"
                },
                {
                    "exact_snippets": [
                        "primary breast cancer"
                    ],
                    "criterion": "breast cancer",
                    "requirement_type": "type",
                    "expected_value": "primary"
                }
            ]
        },
        {
            "line": "* Planned to start docetaxel component of FEC-D or AC-D, or first cycle of; dose-dense AC-T, TC, FEC-D or TAC chemotherapy",
            "criterions": [
                {
                    "exact_snippets": [
                        "Planned to start docetaxel component of FEC-D or AC-D"
                    ],
                    "criterion": "docetaxel component of FEC-D or AC-D",
                    "requirement_type": "planned start",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "first cycle of; dose-dense AC-T, TC, FEC-D or TAC chemotherapy"
                    ],
                    "criterion": "dose-dense AC-T, TC, FEC-D or TAC chemotherapy",
                    "requirement_type": "first cycle",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* Able to provide verbal consent",
            "criterions": [
                {
                    "exact_snippets": [
                        "Able to provide verbal consent"
                    ],
                    "criterion": "verbal consent",
                    "requirement_type": "ability",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": [
                        "Healthy volunteers allowed"
                    ],
                    "criterion": "volunteer health status",
                    "requirement_type": "allowance",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "Must have minimum age of 19 Years",
            "criterions": [
                {
                    "exact_snippets": [
                        "minimum age of 19 Years"
                    ],
                    "criterion": "age",
                    "requirement_type": "minimum",
                    "expected_value": {
                        "operator": ">=",
                        "value": 19
                    }
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Contraindication to Filgrastim",
            "criterions": [
                {
                    "exact_snippets": [
                        "Contraindication to Filgrastim"
                    ],
                    "criterion": "Filgrastim",
                    "requirement_type": "contraindication",
                    "expected_value": true
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [
        {
            "line": "* ≥19 years of age",
            "criterions": [
                {
                    "exact_snippets": [
                        ">=19 years of age"
                    ],
                    "criterion": "age",
                    "requirement_type": "range",
                    "expected_value": {
                        "comparisons": [
                            {
                                "operator": ">=",
                                "value": 19
                            }
                        ]
                    }
                }
            ]
        }
    ],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}