{
    "info": {
        "nct_id": "NCT02369211",
        "official_title": "Pharmacoeconomics and Related Patient Outcomes of Multi-dose Intravenous Acetaminophen (OFIRMEV) in Patients Undergoing Robotic-assisted Laparoscopic Prostatectomy",
        "inclusion_criteria": "* Patients undergoing robotic-assisted laparoscopic prostatectomy\n* ≥18 years old males\n* American Society of Anesthesiologists class 1-4\nHealthy volunteers allowed\nMust be MALE\nMust have minimum age of 18 Years\nMust have maximum age of 85 Years",
        "exclusion_criteria": "* Chronic opiate use\n* Liver disease (known history of hepatitis B or C, cirrhosis, nonalcoholic steatohepatitis, history of alcoholism, liver function test results greater than 3 times upper limit of normal in the past 3 months)\n* Allergy/hypersensitivity to acetaminophen\n* Patients with baseline dementia\n* Chronic diathesis\n* Chronic kidney disease",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Patients undergoing robotic-assisted laparoscopic prostatectomy",
            "criterions": [
                {
                    "exact_snippets": [
                        "Patients undergoing robotic-assisted laparoscopic prostatectomy"
                    ],
                    "criterion": "robotic-assisted laparoscopic prostatectomy",
                    "requirement_type": "undergoing",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* American Society of Anesthesiologists class 1-4",
            "criterions": [
                {
                    "exact_snippets": [
                        "American Society of Anesthesiologists class 1-4"
                    ],
                    "criterion": "American Society of Anesthesiologists class",
                    "requirement_type": "range",
                    "expected_value": {
                        "comparisons": [
                            {
                                "operator": ">=",
                                "value": 1
                            },
                            {
                                "operator": "<=",
                                "value": 4
                            }
                        ]
                    }
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": [
                        "Healthy volunteers allowed"
                    ],
                    "criterion": "healthy volunteers",
                    "requirement_type": "participation",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "Must be MALE",
            "criterions": [
                {
                    "exact_snippets": [
                        "Must be MALE"
                    ],
                    "criterion": "gender",
                    "requirement_type": "specificity",
                    "expected_value": "male"
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": [
                        "minimum age of 18 Years"
                    ],
                    "criterion": "age",
                    "requirement_type": "minimum",
                    "expected_value": {
                        "operator": ">=",
                        "value": 18
                    }
                }
            ]
        },
        {
            "line": "Must have maximum age of 85 Years",
            "criterions": [
                {
                    "exact_snippets": [
                        "maximum age of 85 Years"
                    ],
                    "criterion": "age",
                    "requirement_type": "maximum",
                    "expected_value": {
                        "operator": "<=",
                        "value": 85
                    }
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Chronic opiate use",
            "criterions": [
                {
                    "exact_snippets": [
                        "Chronic opiate use"
                    ],
                    "criterion": "opiate use",
                    "requirement_type": "chronicity",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* Allergy/hypersensitivity to acetaminophen",
            "criterions": [
                {
                    "exact_snippets": [
                        "Allergy/hypersensitivity to acetaminophen"
                    ],
                    "criterion": "acetaminophen",
                    "requirement_type": "allergy/hypersensitivity",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* Patients with baseline dementia",
            "criterions": [
                {
                    "exact_snippets": [
                        "baseline dementia"
                    ],
                    "criterion": "dementia",
                    "requirement_type": "presence",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* Chronic diathesis",
            "criterions": [
                {
                    "exact_snippets": [
                        "Chronic diathesis"
                    ],
                    "criterion": "chronic diathesis",
                    "requirement_type": "presence",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* Chronic kidney disease",
            "criterions": [
                {
                    "exact_snippets": [
                        "Chronic kidney disease"
                    ],
                    "criterion": "chronic kidney disease",
                    "requirement_type": "presence",
                    "expected_value": true
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [
        {
            "line": "* ≥18 years old males",
            "criterions": [
                {
                    "exact_snippets": [
                        ">=18 years old"
                    ],
                    "criterion": "age",
                    "requirement_type": "minimum",
                    "expected_value": {
                        "operator": ">=",
                        "value": 18
                    }
                },
                {
                    "exact_snippets": [
                        "males"
                    ],
                    "criterion": "gender",
                    "requirement_type": "specific",
                    "expected_value": "male"
                }
            ]
        }
    ],
    "failed_exclusion": [
        {
            "line": "* Liver disease (known history of hepatitis B or C, cirrhosis, nonalcoholic steatohepatitis, history of alcoholism, liver function test results greater than 3 times upper limit of normal in the past 3 months)",
            "criterions": [
                {
                    "exact_snippets": [
                        "Liver disease"
                    ],
                    "criterion": "liver disease",
                    "requirement_type": "presence",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "known history of hepatitis B"
                    ],
                    "criterion": "hepatitis B",
                    "requirement_type": "history",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "known history of hepatitis C"
                    ],
                    "criterion": "hepatitis C",
                    "requirement_type": "history",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "cirrhosis"
                    ],
                    "criterion": "cirrhosis",
                    "requirement_type": "presence",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "nonalcoholic steatohepatitis"
                    ],
                    "criterion": "nonalcoholic steatohepatitis",
                    "requirement_type": "presence",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "history of alcoholism"
                    ],
                    "criterion": "alcoholism",
                    "requirement_type": "history",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "liver function test results greater than 3 times upper limit of normal in the past 3 months"
                    ],
                    "criterion": "liver function test results",
                    "requirement_type": "quantity",
                    "expected_value": {
                        "comparisons": [
                            {
                                "operator": ">",
                                "value": 3
                            }
                        ]
                    }
                }
            ]
        }
    ],
    "failed_miscellaneous": []
}