{
    "info": {
        "nct_id": "NCT06798857",
        "official_title": "Exploration of the Relationship Between Mismatch Repair Status of Colorectal Cancer and Lymph Node Metastasis Patterns and Pathological High-risk Factors",
        "inclusion_criteria": "* (1) The preoperative diagnosis was primary colon adenocarcinoma; (2)Undergoing radical surgical treatment; (3)Postoperative immunohistochemistry to determine MMR status; (4)Having complete key clinical and follow-up data.\nHealthy volunteers allowed\nMust have minimum age of 20 Years\nMust have maximum age of 90 Years",
        "exclusion_criteria": "* (1)Previous history of malignant tumors (2)Concurrent distant metastasis (3)Receiving preoperative neoadjuvant therapy.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* (1) The preoperative diagnosis was primary colon adenocarcinoma; (2)Undergoing radical surgical treatment; (3)Postoperative immunohistochemistry to determine MMR status; (4)Having complete key clinical and follow-up data.",
                "criterions": [
                    {
                        "exact_snippets": "preoperative diagnosis was primary colon adenocarcinoma",
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                            "requirement_type": "condition",
                            "expected_value": "primary colon adenocarcinoma"
                        }
                    },
                    {
                        "exact_snippets": "Undergoing radical surgical treatment",
                        "criterion": "surgical treatment",
                        "requirement": {
                            "requirement_type": "type",
                            "expected_value": "radical"
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                    },
                    {
                        "exact_snippets": "Postoperative immunohistochemistry to determine MMR status",
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                        "requirement": {
                            "requirement_type": "determination method",
                            "expected_value": "postoperative immunohistochemistry"
                        }
                    },
                    {
                        "exact_snippets": "Having complete key clinical and follow-up data",
                        "criterion": "clinical and follow-up data",
                        "requirement": {
                            "requirement_type": "completeness",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "preoperative diagnosis was primary colon adenocarcinoma",
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                        "requirement": {
                            "requirement_type": "condition",
                            "expected_value": "primary colon adenocarcinoma"
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                    },
                    {
                        "exact_snippets": "Undergoing radical surgical treatment",
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                        "requirement": {
                            "requirement_type": "type",
                            "expected_value": "radical"
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                    },
                    {
                        "exact_snippets": "Postoperative immunohistochemistry to determine MMR status",
                        "criterion": "MMR status",
                        "requirement": {
                            "requirement_type": "determination method",
                            "expected_value": "postoperative immunohistochemistry"
                        }
                    },
                    {
                        "exact_snippets": "Having complete key clinical and follow-up data",
                        "criterion": "clinical and follow-up data",
                        "requirement": {
                            "requirement_type": "completeness",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
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                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
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            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
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                            "requirement_type": "status",
                            "expected_value": "healthy"
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                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 20 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 20 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 20,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 20 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 20,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have maximum age of 90 Years",
                "criterions": [
                    {
                        "exact_snippets": "maximum age of 90 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 90,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "maximum age of 90 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 90,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* (1)Previous history of malignant tumors (2)Concurrent distant metastasis (3)Receiving preoperative neoadjuvant therapy.",
                "criterions": [
                    {
                        "exact_snippets": "Previous history of malignant tumors",
                        "criterion": "previous history of malignant tumors",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Concurrent distant metastasis",
                        "criterion": "concurrent distant metastasis",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Receiving preoperative neoadjuvant therapy",
                        "criterion": "receiving preoperative neoadjuvant therapy",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "Previous history of malignant tumors",
                        "criterion": "previous history of malignant tumors",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Concurrent distant metastasis",
                        "criterion": "concurrent distant metastasis",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Receiving preoperative neoadjuvant therapy",
                        "criterion": "receiving preoperative neoadjuvant therapy",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}