{
    "info": {
        "nct_id": "NCT06467591",
        "official_title": "Prediction of Long-term Survival and Chemotherapy Benefit in Elderly Advanced Gastric Cancer Patients Based on the mCNS Model of Nutritional Control State Score and Sarcopenia.",
        "inclusion_criteria": "* Confirmed as primary gastric adenocarcinoma by preoperative gastric endoscopy pathology;\n* Underwent R0 laparoscopic radical gastrectomy for gastric cancer;\n* Pathological stage T2-4a-N+;\n* Age ≥ 65 years.\nHealthy volunteers allowed\nMust have minimum age of 65 Years",
        "exclusion_criteria": "* Pathological stage T1 and T2N0;\n* Age < 65 years;\n* Presence of peritoneal or distant metastasis confirmed before or during surgery;\n* Received neoadjuvant chemotherapy before surgery;\n* Remnant gastric cancer;\n* Emergency surgery or palliative exploratory surgery;\n* Preoperative abdominal CT scan not available or preoperative examination time > 1 month;\n* Survival time less than 1 month;\n* Incomplete clinical and pathological data.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* Confirmed as primary gastric adenocarcinoma by preoperative gastric endoscopy pathology;",
                "criterions": [
                    {
                        "exact_snippets": "Confirmed as primary gastric adenocarcinoma",
                        "criterion": "primary gastric adenocarcinoma",
                        "requirement": {
                            "requirement_type": "confirmation",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "preoperative gastric endoscopy pathology",
                        "criterion": "gastric endoscopy pathology",
                        "requirement": {
                            "requirement_type": "timing",
                            "expected_value": "preoperative"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Confirmed as primary gastric adenocarcinoma",
                        "criterion": "primary gastric adenocarcinoma",
                        "requirement": {
                            "requirement_type": "confirmation",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "preoperative gastric endoscopy pathology",
                        "criterion": "gastric endoscopy pathology",
                        "requirement": {
                            "requirement_type": "timing",
                            "expected_value": "preoperative"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Underwent R0 laparoscopic radical gastrectomy for gastric cancer;",
                "criterions": [
                    {
                        "exact_snippets": "Underwent R0 laparoscopic radical gastrectomy",
                        "criterion": "laparoscopic radical gastrectomy",
                        "requirement": {
                            "requirement_type": "procedure",
                            "expected_value": "R0"
                        }
                    },
                    {
                        "exact_snippets": "gastric cancer",
                        "criterion": "gastric cancer",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Underwent R0 laparoscopic radical gastrectomy",
                        "criterion": "laparoscopic radical gastrectomy",
                        "requirement": {
                            "requirement_type": "procedure",
                            "expected_value": "R0"
                        }
                    },
                    {
                        "exact_snippets": "gastric cancer",
                        "criterion": "gastric cancer",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Pathological stage T2-4a-N+;",
                "criterions": [
                    {
                        "exact_snippets": "Pathological stage T2-4a",
                        "criterion": "pathological stage",
                        "requirement": {
                            "requirement_type": "stage",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 2,
                                        "unit": "T"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 4,
                                        "unit": "a"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "N+",
                        "criterion": "nodal involvement",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Pathological stage T2-4a",
                        "criterion": "pathological stage",
                        "requirement": {
                            "requirement_type": "stage",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 2,
                                        "unit": "T"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 4,
                                        "unit": "a"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "N+",
                        "criterion": "nodal involvement",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Age ≥ 65 years.",
                "criterions": [
                    {
                        "exact_snippets": "Age ≥ 65 years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">=",
                                "value": 65,
                                "unit": "years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Age ≥ 65 years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">=",
                                "value": 65,
                                "unit": "years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 65 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 65 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 65,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 65 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 65,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* Pathological stage T1 and T2N0;",
                "criterions": [
                    {
                        "exact_snippets": "Pathological stage T1",
                        "criterion": "pathological stage",
                        "requirement": {
                            "requirement_type": "stage",
                            "expected_value": "T1"
                        }
                    },
                    {
                        "exact_snippets": "Pathological stage ... T2",
                        "criterion": "pathological stage",
                        "requirement": {
                            "requirement_type": "stage",
                            "expected_value": "T2"
                        }
                    },
                    {
                        "exact_snippets": "N0",
                        "criterion": "nodal involvement",
                        "requirement": {
                            "requirement_type": "nodal status",
                            "expected_value": "N0"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "or_criteria": [
                            {
                                "exact_snippets": "Pathological stage T1",
                                "criterion": "pathological stage",
                                "requirement": {
                                    "requirement_type": "stage",
                                    "expected_value": "T1"
                                }
                            },
                            {
                                "exact_snippets": "Pathological stage ... T2",
                                "criterion": "pathological stage",
                                "requirement": {
                                    "requirement_type": "stage",
                                    "expected_value": "T2"
                                }
                            }
                        ]
                    },
                    {
                        "exact_snippets": "N0",
                        "criterion": "nodal involvement",
                        "requirement": {
                            "requirement_type": "nodal status",
                            "expected_value": "N0"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Age < 65 years;",
                "criterions": [
                    {
                        "exact_snippets": "Age < 65 years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": "<",
                                "value": 65,
                                "unit": "years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Age < 65 years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": "<",
                                "value": 65,
                                "unit": "years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Presence of peritoneal or distant metastasis confirmed before or during surgery;",
                "criterions": [
                    {
                        "exact_snippets": "Presence of peritoneal or distant metastasis",
                        "criterion": "peritoneal or distant metastasis",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Presence of peritoneal or distant metastasis",
                        "criterion": "peritoneal or distant metastasis",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Received neoadjuvant chemotherapy before surgery;",
                "criterions": [
                    {
                        "exact_snippets": "Received neoadjuvant chemotherapy before surgery",
                        "criterion": "neoadjuvant chemotherapy",
                        "requirement": {
                            "requirement_type": "timing",
                            "expected_value": "before surgery"
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Received neoadjuvant chemotherapy before surgery",
                    "criterion": "neoadjuvant chemotherapy",
                    "requirement": {
                        "requirement_type": "timing",
                        "expected_value": "before surgery"
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Remnant gastric cancer;",
                "criterions": [
                    {
                        "exact_snippets": "Remnant gastric cancer",
                        "criterion": "remnant gastric cancer",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Remnant gastric cancer",
                    "criterion": "remnant gastric cancer",
                    "requirement": {
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Emergency surgery or palliative exploratory surgery;",
                "criterions": [
                    {
                        "exact_snippets": "Emergency surgery",
                        "criterion": "emergency surgery",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "palliative exploratory surgery",
                        "criterion": "palliative exploratory surgery",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "Emergency surgery",
                        "criterion": "emergency surgery",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "palliative exploratory surgery",
                        "criterion": "palliative exploratory surgery",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Preoperative abdominal CT scan not available or preoperative examination time > 1 month;",
                "criterions": [
                    {
                        "exact_snippets": "Preoperative abdominal CT scan not available",
                        "criterion": "preoperative abdominal CT scan",
                        "requirement": {
                            "requirement_type": "availability",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "preoperative examination time > 1 month",
                        "criterion": "preoperative examination time",
                        "requirement": {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": ">",
                                "value": 1,
                                "unit": "month"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "Preoperative abdominal CT scan not available",
                        "criterion": "preoperative abdominal CT scan",
                        "requirement": {
                            "requirement_type": "availability",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "preoperative examination time > 1 month",
                        "criterion": "preoperative examination time",
                        "requirement": {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": ">",
                                "value": 1,
                                "unit": "month"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Survival time less than 1 month;",
                "criterions": [
                    {
                        "exact_snippets": "Survival time less than 1 month",
                        "criterion": "survival time",
                        "requirement": {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": "<",
                                "value": 1,
                                "unit": "month"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Survival time less than 1 month",
                        "criterion": "survival time",
                        "requirement": {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": "<",
                                "value": 1,
                                "unit": "month"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [
        {
            "identified_line": {
                "line": "* Incomplete clinical and pathological data.",
                "criterions": [
                    {
                        "exact_snippets": "Incomplete clinical and pathological data",
                        "criterion": "clinical data",
                        "requirement": {
                            "requirement_type": "completeness",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Incomplete clinical and pathological data",
                        "criterion": "pathological data",
                        "requirement": {
                            "requirement_type": "completeness",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "Incomplete clinical and pathological data",
                        "criterion": "clinical data",
                        "requirement": {
                            "requirement_type": "completeness",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "Incomplete clinical and pathological data",
                        "criterion": "pathological data",
                        "requirement": {
                            "requirement_type": "completeness",
                            "expected_value": false
                        }
                    }
                ]
            }
        }
    ],
    "failed_miscellaneous": []
}