{
    "info": {
        "nct_id": "NCT06114420",
        "official_title": "Surgical Treatment and Molecular Marker Exploration of Locally Recurrent Colorectal Cancer",
        "inclusion_criteria": "1. Patients with LRCRC who received hospitalization in our center and patients with stage II-III colorectal cancer whose primary surgery was radical surgery\n2. The pathological type of primary tumor is adenocarcinoma\n3. Postoperative local recurrence of colorectal cancer diagnosed by imaging or pathological examination\n4. Have complete medical records and continuous follow-up records\nHealthy volunteers allowed\nMust have minimum age of 18 Years\nMust have maximum age of 85 Years",
        "exclusion_criteria": "1. Familial hereditary colorectal malignant tumors\n2. Past history of other malignant tumors\n3. Recurrence and diffuse peritoneal recurrence occurring within 1 month after surgery",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "1. Patients with LRCRC who received hospitalization in our center and patients with stage II-III colorectal cancer whose primary surgery was radical surgery",
                "criterions": [
                    {
                        "exact_snippets": "Patients with LRCRC",
                        "criterion": "LRCRC",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "received hospitalization in our center",
                        "criterion": "hospitalization in our center",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "patients with stage II-III colorectal cancer",
                        "criterion": "stage II-III colorectal cancer",
                        "requirement": {
                            "requirement_type": "stage",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 2,
                                        "unit": "stage"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 3,
                                        "unit": "stage"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "primary surgery was radical surgery",
                        "criterion": "radical surgery",
                        "requirement": {
                            "requirement_type": "type",
                            "expected_value": "radical"
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "Patients with LRCRC",
                                "criterion": "LRCRC",
                                "requirement": {
                                    "requirement_type": "presence",
                                    "expected_value": true
                                }
                            },
                            {
                                "exact_snippets": "received hospitalization in our center",
                                "criterion": "hospitalization in our center",
                                "requirement": {
                                    "requirement_type": "history",
                                    "expected_value": true
                                }
                            }
                        ]
                    },
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "patients with stage II-III colorectal cancer",
                                "criterion": "stage II-III colorectal cancer",
                                "requirement": {
                                    "requirement_type": "stage",
                                    "expected_value": {
                                        "comparisons": [
                                            {
                                                "operator": ">=",
                                                "value": 2,
                                                "unit": "stage"
                                            },
                                            {
                                                "operator": "<=",
                                                "value": 3,
                                                "unit": "stage"
                                            }
                                        ]
                                    }
                                }
                            },
                            {
                                "exact_snippets": "primary surgery was radical surgery",
                                "criterion": "radical surgery",
                                "requirement": {
                                    "requirement_type": "type",
                                    "expected_value": "radical"
                                }
                            }
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "2. The pathological type of primary tumor is adenocarcinoma",
                "criterions": [
                    {
                        "exact_snippets": "The pathological type of primary tumor is adenocarcinoma",
                        "criterion": "pathological type of primary tumor",
                        "requirement": {
                            "requirement_type": "type",
                            "expected_value": "adenocarcinoma"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "The pathological type of primary tumor is adenocarcinoma",
                        "criterion": "pathological type of primary tumor",
                        "requirement": {
                            "requirement_type": "type",
                            "expected_value": "adenocarcinoma"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "3. Postoperative local recurrence of colorectal cancer diagnosed by imaging or pathological examination",
                "criterions": [
                    {
                        "exact_snippets": "Postoperative local recurrence of colorectal cancer",
                        "criterion": "postoperative local recurrence of colorectal cancer",
                        "requirement": {
                            "requirement_type": "diagnosis method",
                            "expected_value": [
                                "imaging",
                                "pathological examination"
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Postoperative local recurrence of colorectal cancer",
                        "criterion": "postoperative local recurrence of colorectal cancer",
                        "requirement": {
                            "requirement_type": "diagnosis method",
                            "expected_value": [
                                "imaging",
                                "pathological examination"
                            ]
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "4. Have complete medical records and continuous follow-up records",
                "criterions": [
                    {
                        "exact_snippets": "complete medical records",
                        "criterion": "medical records",
                        "requirement": {
                            "requirement_type": "completeness",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "continuous follow-up records",
                        "criterion": "follow-up records",
                        "requirement": {
                            "requirement_type": "continuity",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "complete medical records",
                        "criterion": "medical records",
                        "requirement": {
                            "requirement_type": "completeness",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "continuous follow-up records",
                        "criterion": "follow-up records",
                        "requirement": {
                            "requirement_type": "continuity",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have maximum age of 85 Years",
                "criterions": [
                    {
                        "exact_snippets": "maximum age of 85 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 85,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "maximum age of 85 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 85,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "1. Familial hereditary colorectal malignant tumors",
                "criterions": [
                    {
                        "exact_snippets": "Familial hereditary colorectal malignant tumors",
                        "criterion": "familial hereditary colorectal malignant tumors",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Familial hereditary colorectal malignant tumors",
                    "criterion": "familial hereditary colorectal malignant tumors",
                    "requirement": {
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "2. Past history of other malignant tumors",
                "criterions": [
                    {
                        "exact_snippets": "Past history of other malignant tumors",
                        "criterion": "other malignant tumors",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Past history of other malignant tumors",
                    "criterion": "other malignant tumors",
                    "requirement": {
                        "requirement_type": "history",
                        "expected_value": true
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "3. Recurrence and diffuse peritoneal recurrence occurring within 1 month after surgery",
                "criterions": [
                    {
                        "exact_snippets": "Recurrence",
                        "criterion": "recurrence",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "diffuse peritoneal recurrence",
                        "criterion": "diffuse peritoneal recurrence",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "occurring within 1 month after surgery",
                        "criterion": "time since surgery",
                        "requirement": {
                            "requirement_type": "time frame",
                            "expected_value": {
                                "operator": "<=",
                                "value": 1,
                                "unit": "month"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "Recurrence",
                                "criterion": "recurrence",
                                "requirement": {
                                    "requirement_type": "presence",
                                    "expected_value": true
                                }
                            },
                            {
                                "exact_snippets": "diffuse peritoneal recurrence",
                                "criterion": "diffuse peritoneal recurrence",
                                "requirement": {
                                    "requirement_type": "presence",
                                    "expected_value": true
                                }
                            }
                        ]
                    },
                    {
                        "exact_snippets": "occurring within 1 month after surgery",
                        "criterion": "time since surgery",
                        "requirement": {
                            "requirement_type": "time frame",
                            "expected_value": {
                                "operator": "<=",
                                "value": 1,
                                "unit": "month"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}