{
    "info": {
        "nct_id": "NCT04567082",
        "official_title": "Proteome- and Methylation Profiles in Oropharyngeal Cancer",
        "inclusion_criteria": "* Written informed consent\n* Verified oropharyngeal squamous cell carcinoma\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Other active cancer\n* Uncontrolled comorbidity\n* Unable to give informed consent\n\nControl group:\n\nInclusion Criteria:\n\n* Written informed consent\n* Normal ENT examination\n\nExclusion Criteria:\n\n* Active cancer\n* Uncontrolled comorbidity\n* Unable to give informed consent",
        "miscellaneous_criteria": "Cancer group:"
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* Written informed consent",
                "criterions": [
                    {
                        "exact_snippets": "Written informed consent",
                        "criterion": "informed consent",
                        "requirement": {
                            "requirement_type": "form",
                            "expected_value": "written"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Written informed consent",
                        "criterion": "informed consent",
                        "requirement": {
                            "requirement_type": "form",
                            "expected_value": "written"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Verified oropharyngeal squamous cell carcinoma",
                "criterions": [
                    {
                        "exact_snippets": "Verified oropharyngeal squamous cell carcinoma",
                        "criterion": "oropharyngeal squamous cell carcinoma",
                        "requirement": {
                            "requirement_type": "verification",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Verified oropharyngeal squamous cell carcinoma",
                        "criterion": "oropharyngeal squamous cell carcinoma",
                        "requirement": {
                            "requirement_type": "verification",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* Other active cancer",
                "criterions": [
                    {
                        "exact_snippets": "Other active cancer",
                        "criterion": "active cancer",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Other active cancer",
                    "criterion": "active cancer",
                    "requirement": {
                        "requirement_type": "presence",
                        "expected_value": false
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Uncontrolled comorbidity",
                "criterions": [
                    {
                        "exact_snippets": "Uncontrolled comorbidity",
                        "criterion": "comorbidity",
                        "requirement": {
                            "requirement_type": "control",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Uncontrolled comorbidity",
                        "criterion": "comorbidity",
                        "requirement": {
                            "requirement_type": "control",
                            "expected_value": false
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Unable to give informed consent",
                "criterions": [
                    {
                        "exact_snippets": "Unable to give informed consent",
                        "criterion": "informed consent",
                        "requirement": {
                            "requirement_type": "ability",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Unable to give informed consent",
                    "criterion": "informed consent",
                    "requirement": {
                        "requirement_type": "ability",
                        "expected_value": false
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Written informed consent",
                "criterions": [
                    {
                        "exact_snippets": "Written informed consent",
                        "criterion": "informed consent",
                        "requirement": {
                            "requirement_type": "form",
                            "expected_value": "written"
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Written informed consent",
                    "criterion": "informed consent",
                    "requirement": {
                        "requirement_type": "form",
                        "expected_value": "written"
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Normal ENT examination",
                "criterions": [
                    {
                        "exact_snippets": "Normal ENT examination",
                        "criterion": "ENT examination",
                        "requirement": {
                            "requirement_type": "result",
                            "expected_value": "normal"
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Normal ENT examination",
                    "criterion": "ENT examination",
                    "requirement": {
                        "requirement_type": "result",
                        "expected_value": "normal"
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Active cancer",
                "criterions": [
                    {
                        "exact_snippets": "Active cancer",
                        "criterion": "cancer",
                        "requirement": {
                            "requirement_type": "activity",
                            "expected_value": "active"
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Active cancer",
                    "criterion": "cancer",
                    "requirement": {
                        "requirement_type": "activity",
                        "expected_value": "active"
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Uncontrolled comorbidity",
                "criterions": [
                    {
                        "exact_snippets": "Uncontrolled comorbidity",
                        "criterion": "comorbidity",
                        "requirement": {
                            "requirement_type": "control",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Uncontrolled comorbidity",
                    "criterion": "comorbidity",
                    "requirement": {
                        "requirement_type": "control",
                        "expected_value": false
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Unable to give informed consent",
                "criterions": [
                    {
                        "exact_snippets": "Unable to give informed consent",
                        "criterion": "informed consent",
                        "requirement": {
                            "requirement_type": "ability",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Unable to give informed consent",
                    "criterion": "informed consent",
                    "requirement": {
                        "requirement_type": "ability",
                        "expected_value": false
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "Control group:",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "Inclusion Criteria:",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "Exclusion Criteria:",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        }
    ],
    "miscellaneous_lines": [
        {
            "identified_line": {
                "line": "Cancer group:",
                "criterions": [
                    {
                        "exact_snippets": "Cancer group",
                        "criterion": "cancer group",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Cancer group",
                        "criterion": "cancer group",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        }
    ],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}