{
    "info": {
        "nct_id": "NCT04379960",
        "official_title": "Identification of Immunogenic Neo-epitopes for the Development of Personalised Pancreatic Cancer Vaccines",
        "inclusion_criteria": "* fit and healthy;\n* weigh over 7 stone 12 lbs or 50kg;\n* are aged between 17 and 66 (or 70 if you have given blood before);\n* are over 70 and have given blood in the last two years.\nHealthy volunteers allowed\nMust have minimum age of 17 Years\nMust have maximum age of 70 Years",
        "exclusion_criteria": "* receiving treatment;\n* taking medication;\n* travelling outside of the UK;\n* tattoos;\n* pregnancy;\n* illness;\n* cancer;\n* received blood, blood products or organs.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* fit and healthy;",
                "criterions": [
                    {
                        "exact_snippets": "fit",
                        "criterion": "fitness",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "healthy",
                        "criterion": "health",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "fit",
                        "criterion": "fitness",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "healthy",
                        "criterion": "health",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* are aged between 17 and 66 (or 70 if you have given blood before);",
                "criterions": [
                    {
                        "exact_snippets": "aged between 17 and 66 (or 70 if you have given blood before)",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 17,
                                        "unit": "years"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 66,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "aged between 17 and 66 (or 70 if you have given blood before)",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 17,
                                        "unit": "years"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 70,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "condition": {
                    "exact_snippets": "aged between 17 and 66 (or 70 if you have given blood before)",
                    "criterion": "blood donation history",
                    "requirement": {
                        "requirement_type": "has donated blood before",
                        "expected_value": true
                    }
                },
                "then_criteria": {
                    "exact_snippets": "aged between 17 and 66 (or 70 if you have given blood before)",
                    "criterion": "age",
                    "requirement": {
                        "requirement_type": "range",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": ">=",
                                    "value": 17,
                                    "unit": "years"
                                },
                                {
                                    "operator": "<=",
                                    "value": 70,
                                    "unit": "years"
                                }
                            ]
                        }
                    }
                },
                "else_criteria": {
                    "exact_snippets": "aged between 17 and 66 (or 70 if you have given blood before)",
                    "criterion": "age",
                    "requirement": {
                        "requirement_type": "range",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": ">=",
                                    "value": 17,
                                    "unit": "years"
                                },
                                {
                                    "operator": "<=",
                                    "value": 66,
                                    "unit": "years"
                                }
                            ]
                        }
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* are over 70 and have given blood in the last two years.",
                "criterions": [
                    {
                        "exact_snippets": "are over 70",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">",
                                "value": 70,
                                "unit": "years"
                            }
                        }
                    },
                    {
                        "exact_snippets": "have given blood in the last two years",
                        "criterion": "blood donation",
                        "requirement": {
                            "requirement_type": "time since last donation",
                            "expected_value": {
                                "operator": "<=",
                                "value": 2,
                                "unit": "years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "are over 70",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">",
                                "value": 70,
                                "unit": "years"
                            }
                        }
                    },
                    {
                        "exact_snippets": "have given blood in the last two years",
                        "criterion": "blood donation",
                        "requirement": {
                            "requirement_type": "time since last donation",
                            "expected_value": {
                                "operator": "<=",
                                "value": 2,
                                "unit": "years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 17 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 17 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 17,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 17 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 17,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have maximum age of 70 Years",
                "criterions": [
                    {
                        "exact_snippets": "maximum age of 70 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 70,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "maximum age of 70 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 70,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* receiving treatment;",
                "criterions": [
                    {
                        "exact_snippets": "receiving treatment",
                        "criterion": "treatment status",
                        "requirement": {
                            "requirement_type": "receiving",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "receiving treatment",
                    "criterion": "treatment status",
                    "requirement": {
                        "requirement_type": "receiving",
                        "expected_value": true
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* taking medication;",
                "criterions": [
                    {
                        "exact_snippets": "taking medication",
                        "criterion": "medication",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "taking medication",
                    "criterion": "medication",
                    "requirement": {
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* travelling outside of the UK;",
                "criterions": [
                    {
                        "exact_snippets": "travelling outside of the UK",
                        "criterion": "travel history",
                        "requirement": {
                            "requirement_type": "location",
                            "expected_value": "outside of the UK"
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "travelling outside of the UK",
                    "criterion": "travel history",
                    "requirement": {
                        "requirement_type": "location",
                        "expected_value": "outside of the UK"
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* tattoos;",
                "criterions": [
                    {
                        "exact_snippets": "tattoos",
                        "criterion": "tattoos",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "tattoos",
                    "criterion": "tattoos",
                    "requirement": {
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* pregnancy;",
                "criterions": [
                    {
                        "exact_snippets": "pregnancy",
                        "criterion": "pregnancy",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "pregnancy",
                    "criterion": "pregnancy",
                    "requirement": {
                        "requirement_type": "presence",
                        "expected_value": false
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* illness;",
                "criterions": [
                    {
                        "exact_snippets": "illness",
                        "criterion": "illness",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "illness",
                    "criterion": "illness",
                    "requirement": {
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* cancer;",
                "criterions": [
                    {
                        "exact_snippets": "cancer",
                        "criterion": "cancer",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "cancer",
                        "criterion": "cancer",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* received blood, blood products or organs.",
                "criterions": [
                    {
                        "exact_snippets": "received blood",
                        "criterion": "blood transfusion",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "received ... blood products",
                        "criterion": "blood product transfusion",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "received ... organs",
                        "criterion": "organ transplant",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "received blood",
                        "criterion": "blood transfusion",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "received ... blood products",
                        "criterion": "blood product transfusion",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "received ... organs",
                        "criterion": "organ transplant",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [
        {
            "identified_line": {
                "line": "* weigh over 7 stone 12 lbs or 50kg;",
                "criterions": [
                    {
                        "exact_snippets": "weigh over 7 stone 12 lbs or 50kg",
                        "criterion": "weight",
                        "requirement": {
                            "requirement_type": "minimum weight",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">",
                                        "value": 7.857,
                                        "unit": "stone"
                                    },
                                    {
                                        "operator": ">",
                                        "value": 50,
                                        "unit": "kg"
                                    }
                                ]
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "weigh over 7 stone 12 lbs or 50kg",
                        "criterion": "weight",
                        "requirement": {
                            "requirement_type": "minimum weight",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">",
                                        "value": 7.857,
                                        "unit": "stone"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "weigh over 7 stone 12 lbs or 50kg",
                        "criterion": "weight",
                        "requirement": {
                            "requirement_type": "minimum weight",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">",
                                        "value": 50,
                                        "unit": "kg"
                                    }
                                ]
                            }
                        }
                    }
                ]
            }
        }
    ],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}