{
    "info": {
        "nct_id": "NCT03097276",
        "official_title": "Management of Patients With High C-reactive Protein After Scheduled Resection of Colorectal Cancer: Pilot Study",
        "inclusion_criteria": "* patients aged 18 and older,\n* with a CRP level > 140 mg/L at D3 or CRP > 125 mg/L at D4 following colon and/or rectal resection with anastomosis (protected or not by an upstream stoma)\n* without clinical signs of severe peritonitis (fever, severe sepsis, generalized abdominal contracture)\n* who have provided written informed consent.\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* patients who have undergone intraperitoneal chemotherapy in the context of the surgical treatment for peritoneal carcinomatosis\n* patients with a diagnosis of another infection that could explain the high CRP level,\n* patients who underwent eventration repair at the time of the colorectal resection\n* patients with an obvious indication for revisit surgery\n* persons without health insurance cover\n* adults under guardianship\n* pregnant or beast-feeding women",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* patients aged 18 and older,",
                "criterions": [
                    {
                        "exact_snippets": "patients aged 18 and older",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum age",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
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                    {
                        "exact_snippets": "patients aged 18 and older",
                        "criterion": "age",
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                            "expected_value": {
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                                "value": 18,
                                "unit": "years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* with a CRP level > 140 mg/L at D3 or CRP > 125 mg/L at D4 following colon and/or rectal resection with anastomosis (protected or not by an upstream stoma)",
                "criterions": [
                    {
                        "exact_snippets": "CRP level > 140 mg/L at D3",
                        "criterion": "CRP level at D3",
                        "requirement": {
                            "requirement_type": "comparison",
                            "expected_value": {
                                "operator": ">",
                                "value": 140,
                                "unit": "mg/L"
                            }
                        }
                    },
                    {
                        "exact_snippets": "CRP > 125 mg/L at D4",
                        "criterion": "CRP level at D4",
                        "requirement": {
                            "requirement_type": "comparison",
                            "expected_value": {
                                "operator": ">",
                                "value": 125,
                                "unit": "mg/L"
                            }
                        }
                    },
                    {
                        "exact_snippets": "following colon and/or rectal resection with anastomosis",
                        "criterion": "colon and/or rectal resection with anastomosis",
                        "requirement": {
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                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "protected or not by an upstream stoma",
                        "criterion": "upstream stoma protection",
                        "requirement": {
                            "requirement_type": "protection",
                            "expected_value": [
                                "protected",
                                "not protected"
                            ]
                        }
                    }
                ]
            },
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                    {
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                                "exact_snippets": "CRP level > 140 mg/L at D3",
                                "criterion": "CRP level at D3",
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                                        "unit": "mg/L"
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                            {
                                "exact_snippets": "CRP > 125 mg/L at D4",
                                "criterion": "CRP level at D4",
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                                    "expected_value": {
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                                        "value": 125,
                                        "unit": "mg/L"
                                    }
                                }
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                        ]
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                    {
                        "exact_snippets": "following colon and/or rectal resection with anastomosis",
                        "criterion": "colon and/or rectal resection with anastomosis",
                        "requirement": {
                            "requirement_type": "procedure",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "protected or not by an upstream stoma",
                        "criterion": "upstream stoma protection",
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                            "expected_value": [
                                "protected",
                                "not protected"
                            ]
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* without clinical signs of severe peritonitis (fever, severe sepsis, generalized abdominal contracture)",
                "criterions": [
                    {
                        "exact_snippets": "without clinical signs of severe peritonitis",
                        "criterion": "severe peritonitis",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "fever",
                        "criterion": "fever",
                        "requirement": {
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                        }
                    },
                    {
                        "exact_snippets": "severe sepsis",
                        "criterion": "severe sepsis",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "generalized abdominal contracture",
                        "criterion": "generalized abdominal contracture",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
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                                {
                                    "exact_snippets": "without clinical signs of severe peritonitis",
                                    "criterion": "severe peritonitis",
                                    "requirement": {
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                                        "expected_value": false
                                    }
                                },
                                {
                                    "exact_snippets": "fever",
                                    "criterion": "fever",
                                    "requirement": {
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                                    }
                                },
                                {
                                    "exact_snippets": "severe sepsis",
                                    "criterion": "severe sepsis",
                                    "requirement": {
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                                        "expected_value": false
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                                },
                                {
                                    "exact_snippets": "generalized abdominal contracture",
                                    "criterion": "generalized abdominal contracture",
                                    "requirement": {
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                                        "expected_value": false
                                    }
                                }
                            ]
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* who have provided written informed consent.",
                "criterions": [
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                        "exact_snippets": "provided written informed consent",
                        "criterion": "informed consent",
                        "requirement": {
                            "requirement_type": "presence",
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                        }
                    }
                ]
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            "logical_structure": {
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                        "exact_snippets": "provided written informed consent",
                        "criterion": "informed consent",
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                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
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                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
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                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* patients who have undergone intraperitoneal chemotherapy in the context of the surgical treatment for peritoneal carcinomatosis",
                "criterions": [
                    {
                        "exact_snippets": "undergone intraperitoneal chemotherapy",
                        "criterion": "intraperitoneal chemotherapy",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "surgical treatment for peritoneal carcinomatosis",
                        "criterion": "surgical treatment for peritoneal carcinomatosis",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "undergone intraperitoneal chemotherapy",
                        "criterion": "intraperitoneal chemotherapy",
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                            "expected_value": true
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                    },
                    {
                        "exact_snippets": "surgical treatment for peritoneal carcinomatosis",
                        "criterion": "surgical treatment for peritoneal carcinomatosis",
                        "requirement": {
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                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* patients with a diagnosis of another infection that could explain the high CRP level,",
                "criterions": [
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                        "criterion": "another infection",
                        "requirement": {
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                        }
                    },
                    {
                        "exact_snippets": "high CRP level",
                        "criterion": "CRP level",
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                        "criterion": "another infection",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "high CRP level",
                        "criterion": "CRP level",
                        "requirement": {
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                            "expected_value": "high"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* patients who underwent eventration repair at the time of the colorectal resection",
                "criterions": [
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                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "at the time of the colorectal resection",
                        "criterion": "colorectal resection",
                        "requirement": {
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                            "expected_value": "at the time of"
                        }
                    }
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                    }
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                "criterions": [
                    {
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                        "exact_snippets": "without health insurance cover",
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                        }
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                ]
            }
        },
        {
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                "line": "* pregnant or beast-feeding women",
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                        "criterion": "pregnancy",
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                    },
                    {
                        "exact_snippets": "beast-feeding",
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                    }
                ]
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    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}