{
    "info": {
        "nct_id": "NCT02622620",
        "official_title": "",
        "inclusion_criteria": "* Among the patients with high-grade glioma (glioblastoma multiforme or anaplastic astrocytoma), who received concurrent chemoradiation (CCRT) with temozolomide, the patients show the measurable enhancing portion (1 cm in the long diameter according to the RANO criteria) in the immediate f/up MRI after CCRT.\nHealthy volunteers allowed",
        "exclusion_criteria": "* Among the patients with high-grade glioma (glioblastoma multiforme or anaplastic astrocytoma), who received concurrent chemoradiation (CCRT) with temozolomide, the patients do not show the measurable enhancing portion (1 cm in the long diameter according to the RANO criteria) in the immediate f/up MRI after CCRT.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* Among the patients with high-grade glioma (glioblastoma multiforme or anaplastic astrocytoma), who received concurrent chemoradiation (CCRT) with temozolomide, the patients show the measurable enhancing portion (1 cm in the long diameter according to the RANO criteria) in the immediate f/up MRI after CCRT.",
                "criterions": [
                    {
                        "exact_snippets": "patients with high-grade glioma (glioblastoma multiforme or anaplastic astrocytoma)",
                        "criterion": "high-grade glioma",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "received concurrent chemoradiation (CCRT) with temozolomide",
                        "criterion": "concurrent chemoradiation with temozolomide",
                        "requirement": {
                            "requirement_type": "treatment history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "measurable enhancing portion (1 cm in the long diameter according to the RANO criteria)",
                        "criterion": "measurable enhancing portion",
                        "requirement": {
                            "requirement_type": "size",
                            "expected_value": {
                                "operator": ">=",
                                "value": 1,
                                "unit": "cm"
                            }
                        }
                    },
                    {
                        "exact_snippets": "immediate f/up MRI after CCRT",
                        "criterion": "immediate follow-up MRI after CCRT",
                        "requirement": {
                            "requirement_type": "timing",
                            "expected_value": "immediate after CCRT"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "and_criteria": [
                            {
                                "and_criteria": [
                                    {
                                        "exact_snippets": "patients with high-grade glioma (glioblastoma multiforme or anaplastic astrocytoma)",
                                        "criterion": "high-grade glioma",
                                        "requirement": {
                                            "requirement_type": "presence",
                                            "expected_value": true
                                        }
                                    },
                                    {
                                        "exact_snippets": "received concurrent chemoradiation (CCRT) with temozolomide",
                                        "criterion": "concurrent chemoradiation with temozolomide",
                                        "requirement": {
                                            "requirement_type": "treatment history",
                                            "expected_value": true
                                        }
                                    }
                                ]
                            },
                            {
                                "exact_snippets": "immediate f/up MRI after CCRT",
                                "criterion": "immediate follow-up MRI after CCRT",
                                "requirement": {
                                    "requirement_type": "timing",
                                    "expected_value": "immediate after CCRT"
                                }
                            }
                        ]
                    },
                    {
                        "exact_snippets": "measurable enhancing portion (1 cm in the long diameter according to the RANO criteria)",
                        "criterion": "measurable enhancing portion",
                        "requirement": {
                            "requirement_type": "size",
                            "expected_value": {
                                "operator": ">=",
                                "value": 1,
                                "unit": "cm"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* Among the patients with high-grade glioma (glioblastoma multiforme or anaplastic astrocytoma), who received concurrent chemoradiation (CCRT) with temozolomide, the patients do not show the measurable enhancing portion (1 cm in the long diameter according to the RANO criteria) in the immediate f/up MRI after CCRT.",
                "criterions": [
                    {
                        "exact_snippets": "patients with high-grade glioma (glioblastoma multiforme or anaplastic astrocytoma)",
                        "criterion": "high-grade glioma",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "received concurrent chemoradiation (CCRT) with temozolomide",
                        "criterion": "concurrent chemoradiation with temozolomide",
                        "requirement": {
                            "requirement_type": "treatment history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "do not show the measurable enhancing portion (1 cm in the long diameter according to the RANO criteria)",
                        "criterion": "measurable enhancing portion",
                        "requirement": {
                            "requirement_type": "size",
                            "expected_value": {
                                "operator": "<",
                                "value": 1,
                                "unit": "cm"
                            }
                        }
                    },
                    {
                        "exact_snippets": "immediate f/up MRI after CCRT",
                        "criterion": "immediate follow-up MRI after CCRT",
                        "requirement": {
                            "requirement_type": "timing",
                            "expected_value": "immediate"
                        }
                    }
                ]
            },
            "logical_structure": {
                "condition": {
                    "and_criteria": [
                        {
                            "exact_snippets": "patients with high-grade glioma (glioblastoma multiforme or anaplastic astrocytoma)",
                            "criterion": "high-grade glioma",
                            "requirement": {
                                "requirement_type": "presence",
                                "expected_value": true
                            }
                        },
                        {
                            "exact_snippets": "received concurrent chemoradiation (CCRT) with temozolomide",
                            "criterion": "concurrent chemoradiation with temozolomide",
                            "requirement": {
                                "requirement_type": "treatment history",
                                "expected_value": true
                            }
                        }
                    ]
                },
                "then_criteria": {
                    "and_criteria": [
                        {
                            "exact_snippets": "do not show the measurable enhancing portion (1 cm in the long diameter according to the RANO criteria)",
                            "criterion": "measurable enhancing portion",
                            "requirement": {
                                "requirement_type": "size",
                                "expected_value": {
                                    "operator": "<",
                                    "value": 1,
                                    "unit": "cm"
                                }
                            }
                        },
                        {
                            "exact_snippets": "immediate f/up MRI after CCRT",
                            "criterion": "immediate follow-up MRI after CCRT",
                            "requirement": {
                                "requirement_type": "timing",
                                "expected_value": "immediate"
                            }
                        }
                    ]
                },
                "else_criteria": null
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}