{
    "info": {
        "nct_id": "NCT00106691",
        "official_title": "A Randomized, Double-Blind, Placebo-Controlled, Multicenter Efficacy and Safety Study of Toremifene Citrate for the Prevention of Prostate Cancer in Men With High Grade Prostatic Intraepithelial Neoplasia (PIN)",
        "inclusion_criteria": "* Give voluntary signed informed consent in accordance with institutional policies\n* Be male, aged ≥ 30 years\n* Have a diagnosis of high grade PIN from any previous prostate biopsy. The diagnosis of high grade PIN must be confirmed by the central pathologist\n* Have had a prostate biopsy in the last 6 months with a minimum of 10 cores that shows no evidence of cancer as confirmed by the central pathologist; OR, have had 2 prostate biopsies (each with a minimum of 6 cores) in the 12 months prior to screening with at least one of the biopsies occurring within 6 months prior to the screening visit. Both biopsies should have no evidence of cancer as confirmed by the central pathologist\n* Have a serum PSA of ≤ 10 ng/mL\n* Agree to provide tablet containers for tablet counts and to complete a daily diary of study drug intake\n* Agree to use an effective method of contraception, if the partner is of child-bearing age, while on study and for 30 days after the last dose of study medication\n* Have adequate bone marrow, liver and renal function:\n\n  * White Blood Cell (WBC) Count ≥ 3,000/mm3;\n  * Platelet Count ≥ 100,000/mm3;\n  * Bilirubin ≤ 1.5 mg/dL;\n  * AST and ALT < 2x upper limit of normal;\n  * Serum Creatinine ≤ 2.0 mg%\nHealthy volunteers allowed\nMust be MALE\nMust have minimum age of 30 Years",
        "exclusion_criteria": "* Previous exposure to toremifene citrate\n* Have evidence of prostate cancer (local, regional and/or distal metastasis)\n* Have any history of other malignancies (Exceptions include non-melanoma skin cancer or other cancer that has no evidence of tumor reoccurrence 5 years after definitive treatment).\n* Have active systemic viral, bacterial, or fungal infections requiring treatment\n* Have, in the judgment of the investigator, a clinically significant concurrent illness or psychological, familial, sociological, geographical or other concomitant condition that would not permit adequate follow-up and compliance with the study protocol\n* Concurrently being treated with other investigational agents or have participated in an investigational study within 60 days prior to screening\n* Currently taking dutasteride. Subject is eligible if he stops dutasteride for a total washout of 90 days prior to the Screening Visit and agrees not to use dutasteride for the duration of the study.\n* Have previously taken finasteride for greater than two years\n* Currently taking finasteride. Subject is eligible if he stops finasteride for a total washout of 30 days prior to the Screening Visit and agrees not to use finasteride for the duration of the study.\n* Currently taking testosterone or testosterone-like supplements, such as dehydroepiandrosterone (DHEA). Subject is eligible if he stops these agents for a total washout of 30 days prior to the Screening Visit and agrees not to use these agents for the duration of the study.\n* Have a history of taking PC-SPES within the past two years.\n* Currently taking herbal medicine or dietary supplements for prostate health, such as Saw Palmetto (also known as Serenoa Repens).\n\nSubject is eligible if he stops these agents for a total washout of 30 days prior to taking the first dose of study drug and agrees not to use these agents for the duration of the study.\n\nLycopene, vitamin E and selenium are not prohibited and no washout is required. However, vitamin E intake should be limited to less than 400 i.u. per day.\n\n* Have a history of thromboembolic event or disease including deep vein thrombosis, pulmonary embolus, or thrombotic stroke\n* History of chronic hepatitis or cirrhosis",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* Give voluntary signed informed consent in accordance with institutional policies",
                "criterions": [
                    {
                        "exact_snippets": "Give voluntary signed informed consent",
                        "criterion": "informed consent",
                        "requirement": {
                            "requirement_type": "voluntariness",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Give voluntary signed informed consent",
                        "criterion": "informed consent",
                        "requirement": {
                            "requirement_type": "signature",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Give voluntary signed informed consent",
                        "criterion": "informed consent",
                        "requirement": {
                            "requirement_type": "voluntariness",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Give voluntary signed informed consent",
                        "criterion": "informed consent",
                        "requirement": {
                            "requirement_type": "signature",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Be male, aged ≥ 30 years",
                "criterions": [
                    {
                        "exact_snippets": "Be male",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": "male"
                        }
                    },
                    {
                        "exact_snippets": "aged ≥ 30 years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">=",
                                "value": 30,
                                "unit": "years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Be male",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": "male"
                        }
                    },
                    {
                        "exact_snippets": "aged ≥ 30 years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">=",
                                "value": 30,
                                "unit": "years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Have a diagnosis of high grade PIN from any previous prostate biopsy. The diagnosis of high grade PIN must be confirmed by the central pathologist",
                "criterions": [
                    {
                        "exact_snippets": "diagnosis of high grade PIN from any previous prostate biopsy",
                        "criterion": "high grade PIN diagnosis",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "diagnosis of high grade PIN must be confirmed by the central pathologist",
                        "criterion": "high grade PIN diagnosis confirmation",
                        "requirement": {
                            "requirement_type": "confirmation",
                            "expected_value": "central pathologist"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "diagnosis of high grade PIN from any previous prostate biopsy",
                                "criterion": "high grade PIN diagnosis",
                                "requirement": {
                                    "requirement_type": "presence",
                                    "expected_value": true
                                }
                            },
                            {
                                "exact_snippets": "diagnosis of high grade PIN must be confirmed by the central pathologist",
                                "criterion": "high grade PIN diagnosis confirmation",
                                "requirement": {
                                    "requirement_type": "confirmation",
                                    "expected_value": "central pathologist"
                                }
                            }
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Have had a prostate biopsy in the last 6 months with a minimum of 10 cores that shows no evidence of cancer as confirmed by the central pathologist; OR, have had 2 prostate biopsies (each with a minimum of 6 cores) in the 12 months prior to screening with at least one of the biopsies occurring within 6 months prior to the screening visit. Both biopsies should have no evidence of cancer as confirmed by the central pathologist",
                "criterions": [
                    {
                        "exact_snippets": "prostate biopsy in the last 6 months",
                        "criterion": "prostate biopsy",
                        "requirement": {
                            "requirement_type": "time frame",
                            "expected_value": {
                                "operator": "<=",
                                "value": 6,
                                "unit": "months"
                            }
                        }
                    },
                    {
                        "exact_snippets": "minimum of 10 cores",
                        "criterion": "prostate biopsy cores",
                        "requirement": {
                            "requirement_type": "quantity",
                            "expected_value": {
                                "operator": ">=",
                                "value": 10,
                                "unit": "cores"
                            }
                        }
                    },
                    {
                        "exact_snippets": "no evidence of cancer as confirmed by the central pathologist",
                        "criterion": "cancer evidence",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "2 prostate biopsies ... in the 12 months prior to screening",
                        "criterion": "prostate biopsies",
                        "requirement": {
                            "requirement_type": "quantity",
                            "expected_value": {
                                "operator": "=",
                                "value": 2,
                                "unit": "biopsies"
                            }
                        }
                    },
                    {
                        "exact_snippets": "2 prostate biopsies ... in the 12 months prior to screening",
                        "criterion": "prostate biopsies",
                        "requirement": {
                            "requirement_type": "time frame",
                            "expected_value": {
                                "operator": "<=",
                                "value": 12,
                                "unit": "months"
                            }
                        }
                    },
                    {
                        "exact_snippets": "each with a minimum of 6 cores",
                        "criterion": "prostate biopsy cores",
                        "requirement": {
                            "requirement_type": "quantity",
                            "expected_value": {
                                "operator": ">=",
                                "value": 6,
                                "unit": "cores"
                            }
                        }
                    },
                    {
                        "exact_snippets": "at least one of the biopsies occurring within 6 months prior to the screening visit",
                        "criterion": "prostate biopsy timing",
                        "requirement": {
                            "requirement_type": "time frame",
                            "expected_value": {
                                "operator": "<=",
                                "value": 6,
                                "unit": "months"
                            }
                        }
                    },
                    {
                        "exact_snippets": "Both biopsies should have no evidence of cancer as confirmed by the central pathologist",
                        "criterion": "cancer evidence",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "and_criteria": [
                            {
                                "and_criteria": [
                                    {
                                        "exact_snippets": "prostate biopsy in the last 6 months",
                                        "criterion": "prostate biopsy",
                                        "requirement": {
                                            "requirement_type": "time frame",
                                            "expected_value": {
                                                "operator": "<=",
                                                "value": 6,
                                                "unit": "months"
                                            }
                                        }
                                    },
                                    {
                                        "exact_snippets": "minimum of 10 cores",
                                        "criterion": "prostate biopsy cores",
                                        "requirement": {
                                            "requirement_type": "quantity",
                                            "expected_value": {
                                                "operator": ">=",
                                                "value": 10,
                                                "unit": "cores"
                                            }
                                        }
                                    },
                                    {
                                        "exact_snippets": "no evidence of cancer as confirmed by the central pathologist",
                                        "criterion": "cancer evidence",
                                        "requirement": {
                                            "requirement_type": "presence",
                                            "expected_value": false
                                        }
                                    }
                                ]
                            },
                            {
                                "and_criteria": [
                                    {
                                        "exact_snippets": "2 prostate biopsies ... in the 12 months prior to screening",
                                        "criterion": "prostate biopsies",
                                        "requirement": {
                                            "requirement_type": "quantity",
                                            "expected_value": {
                                                "operator": "=",
                                                "value": 2,
                                                "unit": "biopsies"
                                            }
                                        }
                                    },
                                    {
                                        "exact_snippets": "2 prostate biopsies ... in the 12 months prior to screening",
                                        "criterion": "prostate biopsies",
                                        "requirement": {
                                            "requirement_type": "time frame",
                                            "expected_value": {
                                                "operator": "<=",
                                                "value": 12,
                                                "unit": "months"
                                            }
                                        }
                                    },
                                    {
                                        "exact_snippets": "each with a minimum of 6 cores",
                                        "criterion": "prostate biopsy cores",
                                        "requirement": {
                                            "requirement_type": "quantity",
                                            "expected_value": {
                                                "operator": ">=",
                                                "value": 6,
                                                "unit": "cores"
                                            }
                                        }
                                    },
                                    {
                                        "exact_snippets": "at least one of the biopsies occurring within 6 months prior to the screening visit",
                                        "criterion": "prostate biopsy timing",
                                        "requirement": {
                                            "requirement_type": "time frame",
                                            "expected_value": {
                                                "operator": "<=",
                                                "value": 6,
                                                "unit": "months"
                                            }
                                        }
                                    },
                                    {
                                        "exact_snippets": "Both biopsies should have no evidence of cancer as confirmed by the central pathologist",
                                        "criterion": "cancer evidence",
                                        "requirement": {
                                            "requirement_type": "presence",
                                            "expected_value": false
                                        }
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "2 prostate biopsies ... in the 12 months prior to screening",
                                "criterion": "prostate biopsies",
                                "requirement": {
                                    "requirement_type": "quantity",
                                    "expected_value": {
                                        "operator": "=",
                                        "value": 2,
                                        "unit": "biopsies"
                                    }
                                }
                            },
                            {
                                "exact_snippets": "2 prostate biopsies ... in the 12 months prior to screening",
                                "criterion": "prostate biopsies",
                                "requirement": {
                                    "requirement_type": "time frame",
                                    "expected_value": {
                                        "operator": "<=",
                                        "value": 12,
                                        "unit": "months"
                                    }
                                }
                            },
                            {
                                "exact_snippets": "each with a minimum of 6 cores",
                                "criterion": "prostate biopsy cores",
                                "requirement": {
                                    "requirement_type": "quantity",
                                    "expected_value": {
                                        "operator": ">=",
                                        "value": 6,
                                        "unit": "cores"
                                    }
                                }
                            },
                            {
                                "exact_snippets": "at least one of the biopsies occurring within 6 months prior to the screening visit",
                                "criterion": "prostate biopsy timing",
                                "requirement": {
                                    "requirement_type": "time frame",
                                    "expected_value": {
                                        "operator": "<=",
                                        "value": 6,
                                        "unit": "months"
                                    }
                                }
                            },
                            {
                                "exact_snippets": "Both biopsies should have no evidence of cancer as confirmed by the central pathologist",
                                "criterion": "cancer evidence",
                                "requirement": {
                                    "requirement_type": "presence",
                                    "expected_value": false
                                }
                            }
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Have a serum PSA of ≤ 10 ng/mL",
                "criterions": [
                    {
                        "exact_snippets": "serum PSA of ≤ 10 ng/mL",
                        "criterion": "serum PSA",
                        "requirement": {
                            "requirement_type": "level",
                            "expected_value": {
                                "operator": "<=",
                                "value": 10,
                                "unit": "ng/mL"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "serum PSA of ≤ 10 ng/mL",
                        "criterion": "serum PSA",
                        "requirement": {
                            "requirement_type": "level",
                            "expected_value": {
                                "operator": "<=",
                                "value": 10,
                                "unit": "ng/mL"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Serum Creatinine ≤ 2.0 mg%",
                "criterions": [
                    {
                        "exact_snippets": "Serum Creatinine ≤ 2.0 mg%",
                        "criterion": "serum creatinine",
                        "requirement": {
                            "requirement_type": "level",
                            "expected_value": {
                                "operator": "<=",
                                "value": 2.0,
                                "unit": "mg%"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Serum Creatinine ≤ 2.0 mg%",
                        "criterion": "serum creatinine",
                        "requirement": {
                            "requirement_type": "level",
                            "expected_value": {
                                "operator": "<=",
                                "value": 2.0,
                                "unit": "mg%"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must be MALE",
                "criterions": [
                    {
                        "exact_snippets": "MALE",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "expected_value",
                            "expected_value": "male"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "MALE",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "expected_value",
                            "expected_value": "male"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 30 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 30 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 30,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 30 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 30,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Agree to provide tablet containers for tablet counts and to complete a daily diary of study drug intake",
                "criterions": [
                    {
                        "exact_snippets": "Agree to provide tablet containers for tablet counts",
                        "criterion": "tablet containers",
                        "requirement": {
                            "requirement_type": "agreement",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "agree ... to complete a daily diary of study drug intake",
                        "criterion": "daily diary of study drug intake",
                        "requirement": {
                            "requirement_type": "agreement",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Agree to provide tablet containers for tablet counts",
                        "criterion": "tablet containers",
                        "requirement": {
                            "requirement_type": "agreement",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "agree ... to complete a daily diary of study drug intake",
                        "criterion": "daily diary of study drug intake",
                        "requirement": {
                            "requirement_type": "agreement",
                            "expected_value": true
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* Previous exposure to toremifene citrate",
                "criterions": [
                    {
                        "exact_snippets": "Previous exposure to toremifene citrate",
                        "criterion": "exposure to toremifene citrate",
                        "requirement": {
                            "requirement_type": "previous exposure",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Previous exposure to toremifene citrate",
                    "criterion": "exposure to toremifene citrate",
                    "requirement": {
                        "requirement_type": "previous exposure",
                        "expected_value": true
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Have any history of other malignancies (Exceptions include non-melanoma skin cancer or other cancer that has no evidence of tumor reoccurrence 5 years after definitive treatment).",
                "criterions": [
                    {
                        "exact_snippets": "Have any history of other malignancies",
                        "criterion": "history of other malignancies",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "Exceptions include non-melanoma skin cancer",
                        "criterion": "non-melanoma skin cancer",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "other cancer that has no evidence of tumor reoccurrence 5 years after definitive treatment",
                        "criterion": "other cancer with no evidence of tumor reoccurrence",
                        "requirement": {
                            "requirement_type": "time since definitive treatment",
                            "expected_value": {
                                "operator": ">=",
                                "value": 5,
                                "unit": "years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "not_criteria": {
                            "and_criteria": [
                                {
                                    "exact_snippets": "Have any history of other malignancies",
                                    "criterion": "history of other malignancies",
                                    "requirement": {
                                        "requirement_type": "presence",
                                        "expected_value": false
                                    }
                                },
                                {
                                    "not_criteria": {
                                        "exact_snippets": "Exceptions include non-melanoma skin cancer",
                                        "criterion": "non-melanoma skin cancer",
                                        "requirement": {
                                            "requirement_type": "presence",
                                            "expected_value": true
                                        }
                                    }
                                },
                                {
                                    "not_criteria": {
                                        "exact_snippets": "other cancer that has no evidence of tumor reoccurrence 5 years after definitive treatment",
                                        "criterion": "other cancer with no evidence of tumor reoccurrence",
                                        "requirement": {
                                            "requirement_type": "time since definitive treatment",
                                            "expected_value": {
                                                "operator": ">=",
                                                "value": 5,
                                                "unit": "years"
                                            }
                                        }
                                    }
                                }
                            ]
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Have active systemic viral, bacterial, or fungal infections requiring treatment",
                "criterions": [
                    {
                        "exact_snippets": "active systemic viral, bacterial, or fungal infections requiring treatment",
                        "criterion": "systemic infections",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "active systemic viral, bacterial, or fungal infections requiring treatment",
                        "criterion": "systemic infections",
                        "requirement": {
                            "requirement_type": "treatment requirement",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "active systemic viral, bacterial, or fungal infections requiring treatment",
                                "criterion": "systemic infections",
                                "requirement": {
                                    "requirement_type": "presence",
                                    "expected_value": true
                                }
                            },
                            {
                                "exact_snippets": "active systemic viral, bacterial, or fungal infections requiring treatment",
                                "criterion": "systemic infections",
                                "requirement": {
                                    "requirement_type": "treatment requirement",
                                    "expected_value": true
                                }
                            }
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Concurrently being treated with other investigational agents or have participated in an investigational study within 60 days prior to screening",
                "criterions": [
                    {
                        "exact_snippets": "Concurrently being treated with other investigational agents",
                        "criterion": "treatment with investigational agents",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "participated in an investigational study within 60 days prior to screening",
                        "criterion": "participation in investigational study",
                        "requirement": {
                            "requirement_type": "time since participation",
                            "expected_value": {
                                "operator": ">=",
                                "value": 60,
                                "unit": "days"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "Concurrently being treated with other investigational agents",
                        "criterion": "treatment with investigational agents",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "participated in an investigational study within 60 days prior to screening",
                        "criterion": "participation in investigational study",
                        "requirement": {
                            "requirement_type": "time since participation",
                            "expected_value": {
                                "operator": ">=",
                                "value": 60,
                                "unit": "days"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Currently taking dutasteride. Subject is eligible if he stops dutasteride for a total washout of 90 days prior to the Screening Visit and agrees not to use dutasteride for the duration of the study.",
                "criterions": [
                    {
                        "exact_snippets": "Currently taking dutasteride",
                        "criterion": "dutasteride usage",
                        "requirement": {
                            "requirement_type": "current usage",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Subject is eligible if he stops dutasteride for a total washout of 90 days prior to the Screening Visit",
                        "criterion": "dutasteride washout period",
                        "requirement": {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": ">=",
                                "value": 90,
                                "unit": "days"
                            }
                        }
                    },
                    {
                        "exact_snippets": "agrees not to use dutasteride for the duration of the study",
                        "criterion": "dutasteride usage during study",
                        "requirement": {
                            "requirement_type": "future usage",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "condition": {
                    "exact_snippets": "Currently taking dutasteride",
                    "criterion": "dutasteride usage",
                    "requirement": {
                        "requirement_type": "current usage",
                        "expected_value": true
                    }
                },
                "then_criteria": {
                    "and_criteria": [
                        {
                            "exact_snippets": "Subject is eligible if he stops dutasteride for a total washout of 90 days prior to the Screening Visit",
                            "criterion": "dutasteride washout period",
                            "requirement": {
                                "requirement_type": "duration",
                                "expected_value": {
                                    "operator": ">=",
                                    "value": 90,
                                    "unit": "days"
                                }
                            }
                        },
                        {
                            "exact_snippets": "agrees not to use dutasteride for the duration of the study",
                            "criterion": "dutasteride usage during study",
                            "requirement": {
                                "requirement_type": "future usage",
                                "expected_value": false
                            }
                        }
                    ]
                },
                "else_criteria": null
            }
        },
        {
            "identified_line": {
                "line": "* Have previously taken finasteride for greater than two years",
                "criterions": [
                    {
                        "exact_snippets": "previously taken finasteride for greater than two years",
                        "criterion": "finasteride usage",
                        "requirement": {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": ">",
                                "value": 2,
                                "unit": "years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "previously taken finasteride for greater than two years",
                        "criterion": "finasteride usage",
                        "requirement": {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": ">",
                                "value": 2,
                                "unit": "years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Currently taking finasteride. Subject is eligible if he stops finasteride for a total washout of 30 days prior to the Screening Visit and agrees not to use finasteride for the duration of the study.",
                "criterions": [
                    {
                        "exact_snippets": "Currently taking finasteride",
                        "criterion": "finasteride usage",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Subject is eligible if he stops finasteride for a total washout of 30 days prior to the Screening Visit",
                        "criterion": "finasteride washout period",
                        "requirement": {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": ">=",
                                "value": 30,
                                "unit": "days"
                            }
                        }
                    },
                    {
                        "exact_snippets": "agrees not to use finasteride for the duration of the study",
                        "criterion": "finasteride usage during study",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "condition": {
                    "exact_snippets": "Currently taking finasteride",
                    "criterion": "finasteride usage",
                    "requirement": {
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                },
                "then_criteria": {
                    "or_criteria": [
                        {
                            "not_criteria": {
                                "exact_snippets": "Subject is eligible if he stops finasteride for a total washout of 30 days prior to the Screening Visit",
                                "criterion": "finasteride washout period",
                                "requirement": {
                                    "requirement_type": "duration",
                                    "expected_value": {
                                        "operator": ">=",
                                        "value": 30,
                                        "unit": "days"
                                    }
                                }
                            }
                        },
                        {
                            "not_criteria": {
                                "exact_snippets": "agrees not to use finasteride for the duration of the study",
                                "criterion": "finasteride usage during study",
                                "requirement": {
                                    "requirement_type": "presence",
                                    "expected_value": false
                                }
                            }
                        }
                    ]
                },
                "else_criteria": null
            }
        },
        {
            "identified_line": {
                "line": "* Currently taking testosterone or testosterone-like supplements, such as dehydroepiandrosterone (DHEA). Subject is eligible if he stops these agents for a total washout of 30 days prior to the Screening Visit and agrees not to use these agents for the duration of the study.",
                "criterions": [
                    {
                        "exact_snippets": "Currently taking testosterone or testosterone-like supplements, such as dehydroepiandrosterone (DHEA).",
                        "criterion": "testosterone or testosterone-like supplements",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "Subject is eligible if he stops these agents for a total washout of 30 days prior to the Screening Visit",
                        "criterion": "washout period for testosterone or testosterone-like supplements",
                        "requirement": {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": ">=",
                                "value": 30,
                                "unit": "days"
                            }
                        }
                    },
                    {
                        "exact_snippets": "agrees not to use these agents for the duration of the study.",
                        "criterion": "use of testosterone or testosterone-like supplements during study",
                        "requirement": {
                            "requirement_type": "agreement",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "condition": {
                    "and_criteria": [
                        {
                            "exact_snippets": "Currently taking testosterone or testosterone-like supplements, such as dehydroepiandrosterone (DHEA).",
                            "criterion": "testosterone or testosterone-like supplements",
                            "requirement": {
                                "requirement_type": "presence",
                                "expected_value": true
                            }
                        },
                        {
                            "exact_snippets": "Subject is eligible if he stops these agents for a total washout of 30 days prior to the Screening Visit",
                            "criterion": "washout period for testosterone or testosterone-like supplements",
                            "requirement": {
                                "requirement_type": "duration",
                                "expected_value": {
                                    "operator": ">=",
                                    "value": 30,
                                    "unit": "days"
                                }
                            }
                        },
                        {
                            "exact_snippets": "agrees not to use these agents for the duration of the study.",
                            "criterion": "use of testosterone or testosterone-like supplements during study",
                            "requirement": {
                                "requirement_type": "agreement",
                                "expected_value": false
                            }
                        }
                    ]
                },
                "then_criteria": null,
                "else_criteria": {
                    "exact_snippets": "Currently taking testosterone or testosterone-like supplements, such as dehydroepiandrosterone (DHEA).",
                    "criterion": "testosterone or testosterone-like supplements",
                    "requirement": {
                        "requirement_type": "presence",
                        "expected_value": false
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Have a history of taking PC-SPES within the past two years.",
                "criterions": [
                    {
                        "exact_snippets": "Have a history of taking PC-SPES within the past two years",
                        "criterion": "PC-SPES intake history",
                        "requirement": {
                            "requirement_type": "time frame",
                            "expected_value": "within the past two years"
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Have a history of taking PC-SPES within the past two years",
                    "criterion": "PC-SPES intake history",
                    "requirement": {
                        "requirement_type": "time frame",
                        "expected_value": "within the past two years"
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Currently taking herbal medicine or dietary supplements for prostate health, such as Saw Palmetto (also known as Serenoa Repens).",
                "criterions": [
                    {
                        "exact_snippets": "Currently taking herbal medicine or dietary supplements for prostate health",
                        "criterion": "herbal medicine or dietary supplements for prostate health",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "such as Saw Palmetto (also known as Serenoa Repens)",
                        "criterion": "Saw Palmetto (Serenoa Repens)",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "Currently taking herbal medicine or dietary supplements for prostate health",
                        "criterion": "herbal medicine or dietary supplements for prostate health",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "such as Saw Palmetto (also known as Serenoa Repens)",
                        "criterion": "Saw Palmetto (Serenoa Repens)",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Subject is eligible if he stops these agents for a total washout of 30 days prior to taking the first dose of study drug and agrees not to use these agents for the duration of the study.",
                "criterions": [
                    {
                        "exact_snippets": "stops these agents for a total washout of 30 days prior to taking the first dose of study drug",
                        "criterion": "washout period for agents",
                        "requirement": {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": ">=",
                                "value": 30,
                                "unit": "days"
                            }
                        }
                    },
                    {
                        "exact_snippets": "agrees not to use these agents for the duration of the study",
                        "criterion": "use of agents during study",
                        "requirement": {
                            "requirement_type": "prohibition",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "not_criteria": {
                            "exact_snippets": "stops these agents for a total washout of 30 days prior to taking the first dose of study drug",
                            "criterion": "washout period for agents",
                            "requirement": {
                                "requirement_type": "duration",
                                "expected_value": {
                                    "operator": ">=",
                                    "value": 30,
                                    "unit": "days"
                                }
                            }
                        }
                    },
                    {
                        "not_criteria": {
                            "exact_snippets": "agrees not to use these agents for the duration of the study",
                            "criterion": "use of agents during study",
                            "requirement": {
                                "requirement_type": "prohibition",
                                "expected_value": true
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Lycopene, vitamin E and selenium are not prohibited and no washout is required. However, vitamin E intake should be limited to less than 400 i.u. per day.",
                "criterions": [
                    {
                        "exact_snippets": "Lycopene, vitamin E and selenium are not prohibited",
                        "criterion": "lycopene",
                        "requirement": {
                            "requirement_type": "prohibition",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "Lycopene, vitamin E and selenium are not prohibited",
                        "criterion": "selenium",
                        "requirement": {
                            "requirement_type": "prohibition",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "Lycopene, vitamin E and selenium are not prohibited",
                        "criterion": "vitamin E",
                        "requirement": {
                            "requirement_type": "prohibition",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "no washout is required",
                        "criterion": "washout",
                        "requirement": {
                            "requirement_type": "requirement",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "vitamin E intake should be limited to less than 400 i.u. per day",
                        "criterion": "vitamin E intake",
                        "requirement": {
                            "requirement_type": "limit",
                            "expected_value": {
                                "operator": "<",
                                "value": 400,
                                "unit": "i.u. per day"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Lycopene, vitamin E and selenium are not prohibited",
                        "criterion": "lycopene",
                        "requirement": {
                            "requirement_type": "prohibition",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "Lycopene, vitamin E and selenium are not prohibited",
                        "criterion": "selenium",
                        "requirement": {
                            "requirement_type": "prohibition",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "Lycopene, vitamin E and selenium are not prohibited",
                        "criterion": "vitamin E",
                        "requirement": {
                            "requirement_type": "prohibition",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "no washout is required",
                        "criterion": "washout",
                        "requirement": {
                            "requirement_type": "requirement",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "vitamin E intake should be limited to less than 400 i.u. per day",
                        "criterion": "vitamin E intake",
                        "requirement": {
                            "requirement_type": "limit",
                            "expected_value": {
                                "operator": "<",
                                "value": 400,
                                "unit": "i.u. per day"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Have a history of thromboembolic event or disease including deep vein thrombosis, pulmonary embolus, or thrombotic stroke",
                "criterions": [
                    {
                        "exact_snippets": "history of thromboembolic event or disease",
                        "criterion": "thromboembolic event or disease",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "deep vein thrombosis",
                        "criterion": "deep vein thrombosis",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "pulmonary embolus",
                        "criterion": "pulmonary embolus",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "thrombotic stroke",
                        "criterion": "thrombotic stroke",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "history of thromboembolic event or disease",
                                "criterion": "thromboembolic event or disease",
                                "requirement": {
                                    "requirement_type": "history",
                                    "expected_value": true
                                }
                            },
                            {
                                "or_criteria": [
                                    {
                                        "exact_snippets": "deep vein thrombosis",
                                        "criterion": "deep vein thrombosis",
                                        "requirement": {
                                            "requirement_type": "history",
                                            "expected_value": true
                                        }
                                    },
                                    {
                                        "exact_snippets": "pulmonary embolus",
                                        "criterion": "pulmonary embolus",
                                        "requirement": {
                                            "requirement_type": "history",
                                            "expected_value": true
                                        }
                                    },
                                    {
                                        "exact_snippets": "thrombotic stroke",
                                        "criterion": "thrombotic stroke",
                                        "requirement": {
                                            "requirement_type": "history",
                                            "expected_value": true
                                        }
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "exact_snippets": "deep vein thrombosis",
                        "criterion": "deep vein thrombosis",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "pulmonary embolus",
                        "criterion": "pulmonary embolus",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "thrombotic stroke",
                        "criterion": "thrombotic stroke",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* History of chronic hepatitis or cirrhosis",
                "criterions": [
                    {
                        "exact_snippets": "History of chronic hepatitis",
                        "criterion": "chronic hepatitis",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "History of ... cirrhosis",
                        "criterion": "cirrhosis",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "History of chronic hepatitis",
                        "criterion": "chronic hepatitis",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "History of ... cirrhosis",
                        "criterion": "cirrhosis",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [
        {
            "identified_line": {
                "line": "* Agree to use an effective method of contraception, if the partner is of child-bearing age, while on study and for 30 days after the last dose of study medication",
                "criterions": [
                    {
                        "exact_snippets": "Agree to use an effective method of contraception",
                        "criterion": "contraception use",
                        "requirement": {
                            "requirement_type": "agreement",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "if the partner is of child-bearing age",
                        "criterion": "partner's child-bearing age",
                        "requirement": {
                            "requirement_type": "condition",
                            "expected_value": "child-bearing age"
                        }
                    },
                    {
                        "exact_snippets": "while on study and for 30 days after the last dose of study medication",
                        "criterion": "contraception duration",
                        "requirement": {
                            "requirement_type": "duration",
                            "expected_value": "while on study and for 30 days after the last dose of study medication"
                        }
                    }
                ]
            },
            "logical_structure": {
                "exact_snippets": "failed",
                "criterion": "failed",
                "requirement": {
                    "requirement_type": "failed",
                    "expected_value": "failed"
                }
            }
        },
        {
            "identified_line": {
                "line": "* Have adequate bone marrow, liver and renal function:",
                "criterions": [
                    {
                        "exact_snippets": "adequate bone marrow ... function",
                        "criterion": "bone marrow function",
                        "requirement": {
                            "requirement_type": "adequacy",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "adequate ... liver ... function",
                        "criterion": "liver function",
                        "requirement": {
                            "requirement_type": "adequacy",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "adequate ... renal function",
                        "criterion": "renal function",
                        "requirement": {
                            "requirement_type": "adequacy",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "exact_snippets": "failed",
                "criterion": "failed",
                "requirement": {
                    "requirement_type": "failed",
                    "expected_value": "failed"
                }
            }
        },
        {
            "identified_line": {
                "line": "* White Blood Cell (WBC) Count ≥ 3,000/mm3;",
                "criterions": [
                    {
                        "exact_snippets": "White Blood Cell (WBC) Count ≥ 3,000/mm3",
                        "criterion": "White Blood Cell (WBC) Count",
                        "requirement": {
                            "requirement_type": "quantity",
                            "expected_value": {
                                "operator": ">=",
                                "value": 3000,
                                "unit": "mm3"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "exact_snippets": "failed",
                "criterion": "failed",
                "requirement": {
                    "requirement_type": "failed",
                    "expected_value": "failed"
                }
            }
        },
        {
            "identified_line": {
                "line": "* Platelet Count ≥ 100,000/mm3;",
                "criterions": [
                    {
                        "exact_snippets": "Platelet Count ≥ 100,000/mm3",
                        "criterion": "platelet count",
                        "requirement": {
                            "requirement_type": "quantity",
                            "expected_value": {
                                "operator": ">=",
                                "value": 100000,
                                "unit": "mm3"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "exact_snippets": "failed",
                "criterion": "failed",
                "requirement": {
                    "requirement_type": "failed",
                    "expected_value": "failed"
                }
            }
        },
        {
            "identified_line": {
                "line": "* Bilirubin ≤ 1.5 mg/dL;",
                "criterions": [
                    {
                        "exact_snippets": "Bilirubin ≤ 1.5 mg/dL",
                        "criterion": "bilirubin level",
                        "requirement": {
                            "requirement_type": "level",
                            "expected_value": {
                                "operator": "<=",
                                "value": 1.5,
                                "unit": "mg/dL"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "exact_snippets": "failed",
                "criterion": "failed",
                "requirement": {
                    "requirement_type": "failed",
                    "expected_value": "failed"
                }
            }
        },
        {
            "identified_line": {
                "line": "* AST and ALT < 2x upper limit of normal;",
                "criterions": [
                    {
                        "exact_snippets": "AST and ALT < 2x upper limit of normal",
                        "criterion": "AST",
                        "requirement": {
                            "requirement_type": "level",
                            "expected_value": {
                                "operator": "<",
                                "value": 2,
                                "unit": "x upper limit of normal"
                            }
                        }
                    },
                    {
                        "exact_snippets": "AST and ALT < 2x upper limit of normal",
                        "criterion": "ALT",
                        "requirement": {
                            "requirement_type": "level",
                            "expected_value": {
                                "operator": "<",
                                "value": 2,
                                "unit": "x upper limit of normal"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "exact_snippets": "failed",
                "criterion": "failed",
                "requirement": {
                    "requirement_type": "failed",
                    "expected_value": "failed"
                }
            }
        }
    ],
    "failed_exclusion": [
        {
            "identified_line": {
                "line": "* Have evidence of prostate cancer (local, regional and/or distal metastasis)",
                "criterions": [
                    {
                        "exact_snippets": "evidence of prostate cancer",
                        "criterion": "prostate cancer",
                        "requirement": {
                            "requirement_type": "evidence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "local, regional and/or distal metastasis",
                        "criterion": "metastasis",
                        "requirement": {
                            "requirement_type": "location",
                            "expected_value": [
                                "local",
                                "regional",
                                "distal"
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "evidence of prostate cancer",
                        "criterion": "prostate cancer",
                        "requirement": {
                            "requirement_type": "evidence",
                            "expected_value": true
                        }
                    },
                    {
                        "or_criteria": [
                            {
                                "exact_snippets": "local, regional and/or distal metastasis",
                                "criterion": "metastasis",
                                "requirement": {
                                    "requirement_type": "location",
                                    "expected_value": "local"
                                }
                            },
                            {
                                "exact_snippets": "local, regional and/or distal metastasis",
                                "criterion": "metastasis",
                                "requirement": {
                                    "requirement_type": "location",
                                    "expected_value": "regional"
                                }
                            },
                            {
                                "exact_snippets": "local, regional and/or distal metastasis",
                                "criterion": "metastasis",
                                "requirement": {
                                    "requirement_type": "location",
                                    "expected_value": "distal"
                                }
                            }
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Have, in the judgment of the investigator, a clinically significant concurrent illness or psychological, familial, sociological, geographical or other concomitant condition that would not permit adequate follow-up and compliance with the study protocol",
                "criterions": [
                    {
                        "exact_snippets": "clinically significant concurrent illness",
                        "criterion": "concurrent illness",
                        "requirement": {
                            "requirement_type": "severity",
                            "expected_value": "clinically significant"
                        }
                    },
                    {
                        "exact_snippets": "psychological, familial, sociological, geographical or other concomitant condition",
                        "criterion": "concomitant condition",
                        "requirement": {
                            "requirement_type": "type",
                            "expected_value": [
                                "psychological",
                                "familial",
                                "sociological",
                                "geographical",
                                "other"
                            ]
                        }
                    },
                    {
                        "exact_snippets": "would not permit adequate follow-up and compliance with the study protocol",
                        "criterion": "ability to comply with study protocol",
                        "requirement": {
                            "requirement_type": "capability",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "exact_snippets": "failed",
                "criterion": "failed",
                "requirement": {
                    "requirement_type": "failed",
                    "expected_value": "failed"
                }
            }
        }
    ],
    "failed_miscellaneous": []
}