{
    "info": {
        "nct_id": "NCT06689462",
        "official_title": "Appraisal of the Modified Cancer Cachexia Index in Locally Advanced Gastric Cancer Patients Undergoing Neoadjuvant Chemotherapy",
        "inclusion_criteria": "* (1) locally advanced gastric cancer (cT2-4NxM0) with clinical staging before neoadjuvant chemotherapy, (2) no history of other malignant tumors, (3) no evidence of distant metastasis or invasion of adjacent organs, and (4) patients who underwent radical gastrectomy following neoadjuvant chemotherapy.\nHealthy volunteers allowed\nMust have minimum age of 18 Years\nMust have maximum age of 84 Years",
        "exclusion_criteria": "* (1) history of gastric surgery; (2) acute cardiovascular disease (such as cerebrovascular or coronary artery injury) within the past three months; (3) emergency surgery; (4) active infection or severe systemic immunodeficiency; and (5) incomplete serological, computed tomography, or anthropometric data.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* (1) locally advanced gastric cancer (cT2-4NxM0) with clinical staging before neoadjuvant chemotherapy, (2) no history of other malignant tumors, (3) no evidence of distant metastasis or invasion of adjacent organs, and (4) patients who underwent radical gastrectomy following neoadjuvant chemotherapy.",
            "criterions": [
                {
                    "exact_snippets": "locally advanced gastric cancer (cT2-4NxM0)",
                    "criterion": "gastric cancer",
                    "requirements": [
                        {
                            "requirement_type": "stage",
                            "expected_value": "locally advanced (cT2-4NxM0)"
                        }
                    ]
                },
                {
                    "exact_snippets": "clinical staging before neoadjuvant chemotherapy",
                    "criterion": "clinical staging",
                    "requirements": [
                        {
                            "requirement_type": "timing",
                            "expected_value": "before neoadjuvant chemotherapy"
                        }
                    ]
                },
                {
                    "exact_snippets": "no history of other malignant tumors",
                    "criterion": "history of malignant tumors",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "no evidence of distant metastasis",
                    "criterion": "distant metastasis",
                    "requirements": [
                        {
                            "requirement_type": "evidence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "no evidence of ... invasion of adjacent organs",
                    "criterion": "invasion of adjacent organs",
                    "requirements": [
                        {
                            "requirement_type": "evidence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "patients who underwent radical gastrectomy following neoadjuvant chemotherapy",
                    "criterion": "radical gastrectomy",
                    "requirements": [
                        {
                            "requirement_type": "procedure",
                            "expected_value": "following neoadjuvant chemotherapy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 84 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 84 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 84,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* (1) history of gastric surgery; (2) acute cardiovascular disease (such as cerebrovascular or coronary artery injury) within the past three months; (3) emergency surgery; (4) active infection or severe systemic immunodeficiency; and (5) incomplete serological, computed tomography, or anthropometric data.",
            "criterions": [
                {
                    "exact_snippets": "history of gastric surgery",
                    "criterion": "gastric surgery",
                    "requirements": [
                        {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "acute cardiovascular disease (such as cerebrovascular or coronary artery injury) within the past three months",
                    "criterion": "acute cardiovascular disease",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        },
                        {
                            "requirement_type": "time frame",
                            "expected_value": "within the past three months"
                        }
                    ]
                },
                {
                    "exact_snippets": "emergency surgery",
                    "criterion": "emergency surgery",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "active infection or severe systemic immunodeficiency",
                    "criterion": "active infection",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "active infection or severe systemic immunodeficiency",
                    "criterion": "severe systemic immunodeficiency",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "incomplete serological, computed tomography, or anthropometric data",
                    "criterion": "serological data",
                    "requirements": [
                        {
                            "requirement_type": "completeness",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "incomplete serological, computed tomography, or anthropometric data",
                    "criterion": "computed tomography data",
                    "requirements": [
                        {
                            "requirement_type": "completeness",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "incomplete serological, computed tomography, or anthropometric data",
                    "criterion": "anthropometric data",
                    "requirements": [
                        {
                            "requirement_type": "completeness",
                            "expected_value": false
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}