{
    "info": {
        "nct_id": "NCT06239766",
        "official_title": "Assessing Breast Cancer Risk Prior to Gender-Affirming Chest Masculinization Surgery in Transgender and Gender-Diverse Persons",
        "inclusion_criteria": "1. ≥18 years old.\n2. Assigned female or intersex at birth and identify as non-cisgender.\n3. Any individual considering undergoing gender-affirming chest masculinization surgery\n4. Ability to communicate in English.\n5. Ability to understand a written informed consent document, and the willingness to sign it.\nHealthy volunteers allowed\nMust be FEMALE\nMust have minimum age of 18 Years",
        "exclusion_criteria": "1. <18 years old.\n2. Assigned male sex at birth.\n3. Previously underwent chest masculinization surgery or any form of oncological mastectomy for the purposes of risk-reduction or cancer treatment.\n4. Any previous or current history of breast cancer, including ductal carcina in situ (DCIS).\n5. Inability to communicate in English.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "1. ≥18 years old.",
            "criterions": [
                {
                    "exact_snippets": "≥18 years old",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "2. Assigned female or intersex at birth and identify as non-cisgender.",
            "criterions": [
                {
                    "exact_snippets": "Assigned female or intersex at birth",
                    "criterion": "sex assigned at birth",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": [
                                "female",
                                "intersex"
                            ]
                        }
                    ]
                },
                {
                    "exact_snippets": "identify as non-cisgender",
                    "criterion": "gender identity",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": "non-cisgender"
                        }
                    ]
                }
            ]
        },
        {
            "line": "3. Any individual considering undergoing gender-affirming chest masculinization surgery",
            "criterions": [
                {
                    "exact_snippets": "considering undergoing gender-affirming chest masculinization surgery",
                    "criterion": "gender-affirming chest masculinization surgery",
                    "requirements": [
                        {
                            "requirement_type": "consideration",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "4. Ability to communicate in English.",
            "criterions": [
                {
                    "exact_snippets": "Ability to communicate in English",
                    "criterion": "English communication ability",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "5. Ability to understand a written informed consent document, and the willingness to sign it.",
            "criterions": [
                {
                    "exact_snippets": "Ability to understand a written informed consent document",
                    "criterion": "understanding of informed consent",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "willingness to sign it",
                    "criterion": "willingness to sign informed consent",
                    "requirements": [
                        {
                            "requirement_type": "willingness",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must be FEMALE",
            "criterions": [
                {
                    "exact_snippets": "Must be FEMALE",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "expected_value",
                            "expected_value": "female"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "1. <18 years old.",
            "criterions": [
                {
                    "exact_snippets": "<18 years old",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": "<",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "2. Assigned male sex at birth.",
            "criterions": [
                {
                    "exact_snippets": "Assigned male sex at birth",
                    "criterion": "sex at birth",
                    "requirements": [
                        {
                            "requirement_type": "assigned sex",
                            "expected_value": "male"
                        }
                    ]
                }
            ]
        },
        {
            "line": "3. Previously underwent chest masculinization surgery or any form of oncological mastectomy for the purposes of risk-reduction or cancer treatment.",
            "criterions": [
                {
                    "exact_snippets": "Previously underwent chest masculinization surgery",
                    "criterion": "chest masculinization surgery",
                    "requirements": [
                        {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "any form of oncological mastectomy for the purposes of risk-reduction or cancer treatment",
                    "criterion": "oncological mastectomy",
                    "requirements": [
                        {
                            "requirement_type": "purpose",
                            "expected_value": [
                                "risk-reduction",
                                "cancer treatment"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "4. Any previous or current history of breast cancer, including ductal carcina in situ (DCIS).",
            "criterions": [
                {
                    "exact_snippets": "previous or current history of breast cancer",
                    "criterion": "breast cancer",
                    "requirements": [
                        {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "ductal carcina in situ (DCIS)",
                    "criterion": "ductal carcinoma in situ (DCIS)",
                    "requirements": [
                        {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "5. Inability to communicate in English.",
            "criterions": [
                {
                    "exact_snippets": "Inability to communicate in English",
                    "criterion": "ability to communicate in English",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}