{
    "info": {
        "nct_id": "NCT06166420",
        "official_title": "Offering Home-based Versus Hospital-based HPV Counseling and Testing for Cervical Cancer Screening in Rural West Region of Cameroon: a Randomised Cluster Trial",
        "inclusion_criteria": "* Women aged 30-49 years\n* Ability to understand study procedures and accepting voluntarily to participate by signing an informed consent form (ICF).\n\nNon-inclusion criteria:\n\n* Pregnancy at the time of screening\n* History of cervical cancer screening by HPV test of less than 5 years (for HIV-negative women) or less than 3 years (for HIV positive women).\n* Intra-vaginal treatment\nHealthy volunteers allowed\nMust be FEMALE\nMust have minimum age of 30 Years\nMust have maximum age of 49 Years",
        "exclusion_criteria": "* Symptoms of cervical cancer (e.g. metrorrhagia, known pelvic mass)\n* Severe pre-existing medical conditions (e.g. advanced cancer, terminal renal failure)\n* Women who are not able to comply with the study protocol.\n* Previous hysterectomy\n* Known cervical cancer",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Women aged 30-49 years",
            "criterions": [
                {
                    "exact_snippets": "Women",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "expected_value",
                            "expected_value": "female"
                        }
                    ]
                },
                {
                    "exact_snippets": "aged 30-49 years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 30,
                                        "unit": "years"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 49,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Ability to understand study procedures and accepting voluntarily to participate by signing an informed consent form (ICF).",
            "criterions": [
                {
                    "exact_snippets": "Ability to understand study procedures",
                    "criterion": "understanding of study procedures",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "accepting voluntarily to participate by signing an informed consent form (ICF)",
                    "criterion": "voluntary participation",
                    "requirements": [
                        {
                            "requirement_type": "action",
                            "expected_value": "signing an informed consent form (ICF)"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Pregnancy at the time of screening",
            "criterions": [
                {
                    "exact_snippets": "Pregnancy at the time of screening",
                    "criterion": "pregnancy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Intra-vaginal treatment",
            "criterions": [
                {
                    "exact_snippets": "Intra-vaginal treatment",
                    "criterion": "intra-vaginal treatment",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must be FEMALE",
            "criterions": [
                {
                    "exact_snippets": "Must be FEMALE",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "expected_value",
                            "expected_value": "female"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 30 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 30 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 30,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 49 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 49 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 49,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Symptoms of cervical cancer (e.g. metrorrhagia, known pelvic mass)",
            "criterions": [
                {
                    "exact_snippets": "Symptoms of cervical cancer (e.g. metrorrhagia",
                    "criterion": "metrorrhagia",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "Symptoms of cervical cancer ... known pelvic mass",
                    "criterion": "pelvic mass",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Severe pre-existing medical conditions (e.g. advanced cancer, terminal renal failure)",
            "criterions": [
                {
                    "exact_snippets": "Severe pre-existing medical conditions",
                    "criterion": "pre-existing medical conditions",
                    "requirements": [
                        {
                            "requirement_type": "severity",
                            "expected_value": "severe"
                        }
                    ]
                },
                {
                    "exact_snippets": "advanced cancer",
                    "criterion": "cancer",
                    "requirements": [
                        {
                            "requirement_type": "stage",
                            "expected_value": "advanced"
                        }
                    ]
                },
                {
                    "exact_snippets": "terminal renal failure",
                    "criterion": "renal failure",
                    "requirements": [
                        {
                            "requirement_type": "stage",
                            "expected_value": "terminal"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Women who are not able to comply with the study protocol.",
            "criterions": [
                {
                    "exact_snippets": "Women who are not able to comply with the study protocol.",
                    "criterion": "ability to comply with the study protocol",
                    "requirements": [
                        {
                            "requirement_type": "compliance",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Previous hysterectomy",
            "criterions": [
                {
                    "exact_snippets": "Previous hysterectomy",
                    "criterion": "hysterectomy",
                    "requirements": [
                        {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Known cervical cancer",
            "criterions": [
                {
                    "exact_snippets": "Known cervical cancer",
                    "criterion": "cervical cancer",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [
        {
            "line": "Non-inclusion criteria:",
            "criterions": []
        },
        {
            "line": "* History of cervical cancer screening by HPV test of less than 5 years (for HIV-negative women) or less than 3 years (for HIV positive women).",
            "criterions": [
                {
                    "exact_snippets": "History of cervical cancer screening by HPV test of less than 5 years (for HIV-negative women)",
                    "criterion": "cervical cancer screening by HPV test",
                    "requirements": [
                        {
                            "requirement_type": "history",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": "<",
                                        "value": 5,
                                        "unit": "years"
                                    }
                                ]
                            }
                        },
                        {
                            "requirement_type": "HIV status",
                            "expected_value": "negative"
                        }
                    ]
                },
                {
                    "exact_snippets": "History of cervical cancer screening by HPV test of less than 3 years (for HIV positive women)",
                    "criterion": "cervical cancer screening by HPV test",
                    "requirements": [
                        {
                            "requirement_type": "history",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": "<",
                                        "value": 3,
                                        "unit": "years"
                                    }
                                ]
                            }
                        },
                        {
                            "requirement_type": "HIV status",
                            "expected_value": "positive"
                        }
                    ]
                }
            ]
        }
    ],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}