{
    "info": {
        "nct_id": "NCT05623748",
        "official_title": "Establishment and Application of 3-Dimensional (3-D) Cell Culture Model of Clinical Circulating Tumor Cells (CTCs)",
        "inclusion_criteria": "1. patients who agreed with the content of informed consent of the study protocol\n2. patients who agreed the researcher to review the medical record\n3. adults >20 years old\n4. Patients have the right to asked withdrawing from the trial at any timepoints\n5. meet the following requirements (1)cancer participants:cancer patients with transitional cell carcinoma (2)healthy participants:participants without cancer\nHealthy volunteers allowed\nMust have minimum age of 20 Years",
        "exclusion_criteria": "1. Patients who refused the collection of blood and the reviewing of medical record\n2. The investigators suggest to withdraw",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "1. patients who agreed with the content of informed consent of the study protocol",
            "criterions": [
                {
                    "exact_snippets": "patients who agreed with the content of informed consent",
                    "criterion": "informed consent",
                    "requirements": [
                        {
                            "requirement_type": "agreement",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "2. patients who agreed the researcher to review the medical record",
            "criterions": [
                {
                    "exact_snippets": "patients who agreed the researcher to review the medical record",
                    "criterion": "agreement to medical record review",
                    "requirements": [
                        {
                            "requirement_type": "consent",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "3. adults >20 years old",
            "criterions": [
                {
                    "exact_snippets": "adults >20 years old",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum age",
                            "expected_value": {
                                "operator": ">",
                                "value": 20,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "4. Patients have the right to asked withdrawing from the trial at any timepoints",
            "criterions": [
                {
                    "exact_snippets": "Patients have the right to asked withdrawing from the trial at any timepoints",
                    "criterion": "right to withdraw",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "5. meet the following requirements (1)cancer participants:cancer patients with transitional cell carcinoma (2)healthy participants:participants without cancer",
            "criterions": [
                {
                    "exact_snippets": "cancer participants:cancer patients with transitional cell carcinoma",
                    "criterion": "cancer type",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": "transitional cell carcinoma"
                        }
                    ]
                },
                {
                    "exact_snippets": "healthy participants:participants without cancer",
                    "criterion": "cancer",
                    "requirements": [
                        {
                            "requirement_type": "absence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 20 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 20 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 20,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "1. Patients who refused the collection of blood and the reviewing of medical record",
            "criterions": [
                {
                    "exact_snippets": "refused the collection of blood",
                    "criterion": "blood collection",
                    "requirements": [
                        {
                            "requirement_type": "consent",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "refused ... the reviewing of medical record",
                    "criterion": "medical record review",
                    "requirements": [
                        {
                            "requirement_type": "consent",
                            "expected_value": false
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [
        {
            "line": "2. The investigators suggest to withdraw",
            "criterions": []
        }
    ],
    "failed_miscellaneous": []
}