{
    "info": {
        "nct_id": "NCT05132101",
        "official_title": "Analysis of the Real-world Prescription Pattern of Palbociclib Combination Therapy With Aromatase Inhibitor as a 1st Line Therapy in Metastatic Breast Cancer Patients Using the National Health Insurance Claims Data in South Korea",
        "inclusion_criteria": "* Patients who were prescribed with palbociclib in combination with AI for at least 1 cycle during the index period\n* Patients who were diagnosed with BC during the index period\nHealthy volunteers allowed\nMust be FEMALE\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Male\n* Prescribed with palbociclib during 12-month period preceding the index date",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Patients who were prescribed with palbociclib in combination with AI for at least 1 cycle during the index period",
            "criterions": [
                {
                    "exact_snippets": "prescribed with palbociclib in combination with AI",
                    "criterion": "medication regimen",
                    "requirements": [
                        {
                            "requirement_type": "combination",
                            "expected_value": [
                                "palbociclib",
                                "AI"
                            ]
                        }
                    ]
                },
                {
                    "exact_snippets": "at least 1 cycle during the index period",
                    "criterion": "treatment duration",
                    "requirements": [
                        {
                            "requirement_type": "minimum cycles",
                            "expected_value": {
                                "operator": ">=",
                                "value": 1,
                                "unit": "cycle"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients who were diagnosed with BC during the index period",
            "criterions": [
                {
                    "exact_snippets": "Patients who were diagnosed with BC",
                    "criterion": "BC diagnosis",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must be FEMALE",
            "criterions": [
                {
                    "exact_snippets": "Must be FEMALE",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "expected_value",
                            "expected_value": "female"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Male",
            "criterions": [
                {
                    "exact_snippets": "Male",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": "male"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Prescribed with palbociclib during 12-month period preceding the index date",
            "criterions": [
                {
                    "exact_snippets": "Prescribed with palbociclib during 12-month period preceding the index date",
                    "criterion": "palbociclib prescription",
                    "requirements": [
                        {
                            "requirement_type": "timeframe",
                            "expected_value": "12-month period preceding the index date"
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}