{
    "info": {
        "nct_id": "NCT04913376",
        "official_title": "Effectiveness of Hilotherapy for the Prevention of Oxaliplatin-induced Peripheral Neuropathy and Pain in the Treatment of Gastrointestinal Tumors: A Randomized Controlled Trial",
        "inclusion_criteria": "* 18 years or older\n* Gastro-intestinal tumor, treated in UZ Leuven (University Hospitals of Leuven)\n* Starting oxaliplatin-based treatment\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Already grade 2 or higher peripheral neuropathy\n\nFor a more detailed list, see protocol.",
        "miscellaneous_criteria": "Most important Eligibility Criteria:"
    },
    "inclusion_lines": [
        {
            "line": "* 18 years or older",
            "criterions": [
                {
                    "exact_snippets": "18 years or older",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum age",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Gastro-intestinal tumor, treated in UZ Leuven (University Hospitals of Leuven)",
            "criterions": [
                {
                    "exact_snippets": "Gastro-intestinal tumor",
                    "criterion": "gastro-intestinal tumor",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "treated in UZ Leuven (University Hospitals of Leuven)",
                    "criterion": "treatment location",
                    "requirements": [
                        {
                            "requirement_type": "location",
                            "expected_value": "UZ Leuven (University Hospitals of Leuven)"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Starting oxaliplatin-based treatment",
            "criterions": [
                {
                    "exact_snippets": "Starting oxaliplatin-based treatment",
                    "criterion": "oxaliplatin-based treatment",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "starting"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Already grade 2 or higher peripheral neuropathy",
            "criterions": [
                {
                    "exact_snippets": "grade 2 or higher peripheral neuropathy",
                    "criterion": "peripheral neuropathy",
                    "requirements": [
                        {
                            "requirement_type": "severity",
                            "expected_value": {
                                "operator": ">=",
                                "value": 2,
                                "unit": "grade"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [
        {
            "line": "For a more detailed list, see protocol.",
            "criterions": []
        }
    ],
    "failed_miscellaneous": [
        {
            "line": "Most important Eligibility Criteria:",
            "criterions": []
        }
    ]
}