{
    "info": {
        "nct_id": "NCT04681560",
        "official_title": "The Effect of Polychemotherapy on Endothelial Function Ans Vessel Age in Cancer Patients.",
        "inclusion_criteria": "* Subject has solid cancer\n* Subject is expected to start chemotherapy\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Pregnancy and lactation\n* Severe impaired kidney function\n* Severe hepatic impairment\n* Mental disease\n* Acute myocardial infarction 28 days ago or earlier\n* Acute Cerebrovascular Event 1 month ago or earlier\n* Rhythm disturbance that complicate pulse wave velocity evaluation",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Subject has solid cancer",
            "criterions": [
                {
                    "exact_snippets": "Subject has solid cancer",
                    "criterion": "solid cancer",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Subject is expected to start chemotherapy",
            "criterions": [
                {
                    "exact_snippets": "Subject is expected to start chemotherapy",
                    "criterion": "chemotherapy",
                    "requirements": [
                        {
                            "requirement_type": "expectation",
                            "expected_value": "start"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Pregnancy and lactation",
            "criterions": [
                {
                    "exact_snippets": "Pregnancy",
                    "criterion": "pregnancy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "lactation",
                    "criterion": "lactation",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Severe impaired kidney function",
            "criterions": [
                {
                    "exact_snippets": "Severe impaired kidney function",
                    "criterion": "kidney function",
                    "requirements": [
                        {
                            "requirement_type": "severity",
                            "expected_value": "severe"
                        },
                        {
                            "requirement_type": "impairment",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Severe hepatic impairment",
            "criterions": [
                {
                    "exact_snippets": "Severe hepatic impairment",
                    "criterion": "hepatic impairment",
                    "requirements": [
                        {
                            "requirement_type": "severity",
                            "expected_value": "severe"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Mental disease",
            "criterions": [
                {
                    "exact_snippets": "Mental disease",
                    "criterion": "mental disease",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Acute myocardial infarction 28 days ago or earlier",
            "criterions": [
                {
                    "exact_snippets": "Acute myocardial infarction 28 days ago or earlier",
                    "criterion": "acute myocardial infarction",
                    "requirements": [
                        {
                            "requirement_type": "occurrence",
                            "expected_value": {
                                "operator": "<=",
                                "value": 28,
                                "unit": "days ago"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Acute Cerebrovascular Event 1 month ago or earlier",
            "criterions": [
                {
                    "exact_snippets": "Acute Cerebrovascular Event 1 month ago or earlier",
                    "criterion": "acute cerebrovascular event",
                    "requirements": [
                        {
                            "requirement_type": "occurrence",
                            "expected_value": {
                                "operator": "<=",
                                "value": 1,
                                "unit": "month ago"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Rhythm disturbance that complicate pulse wave velocity evaluation",
            "criterions": [
                {
                    "exact_snippets": "Rhythm disturbance that complicate pulse wave velocity evaluation",
                    "criterion": "rhythm disturbance",
                    "requirements": [
                        {
                            "requirement_type": "complication",
                            "expected_value": "pulse wave velocity evaluation"
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}