{
    "info": {
        "nct_id": "NCT04095091",
        "official_title": "Real-time Tumor Localization and Guidance for Radiotherapy Using Ultrasound (US) and Magnetic Resonance (MR)",
        "inclusion_criteria": "Healthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "",
        "miscellaneous_criteria": "Inclusion Criteria (Healthy Volunteers):\n\n* Must be eighteen (18) years of age or older.\n* Must be able to provide informed consent.\n\nInclusion Criteria (Patients):\n\n* Patients diagnosed with malignancies of the liver.\n\nExclusion Criteria (All):\n\n* Under the age of eighteen (18) years.\n* BMI exceeds the size of the bore of the MRI scanner.\n* Unable or unwilling to provide informed consent.\n* Contraindications, as described in the volunteer consent form, to MR or US scanning such as but not limited to accidental or implanted ferrous metal and/or implanted devices whose function can be disturbed by the main magnetic field, gradient magnetic fields, or radiofrequency energy.\n* Women who are pregnant, suspect they might be pregnant or breastfeeding."
    },
    "inclusion_lines": [
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [],
    "miscellaneous_lines": [
        {
            "line": "Inclusion Criteria (Healthy Volunteers):",
            "criterions": [
                {
                    "exact_snippets": "Healthy Volunteers",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Must be eighteen (18) years of age or older.",
            "criterions": [
                {
                    "exact_snippets": "eighteen (18) years of age or older",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum age",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Must be able to provide informed consent.",
            "criterions": [
                {
                    "exact_snippets": "Must be able to provide informed consent.",
                    "criterion": "informed consent",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients diagnosed with malignancies of the liver.",
            "criterions": [
                {
                    "exact_snippets": "malignancies of the liver",
                    "criterion": "liver malignancy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Under the age of eighteen (18) years.",
            "criterions": [
                {
                    "exact_snippets": "Under the age of eighteen (18) years.",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": "<",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* BMI exceeds the size of the bore of the MRI scanner.",
            "criterions": [
                {
                    "exact_snippets": "BMI exceeds the size of the bore of the MRI scanner.",
                    "criterion": "BMI",
                    "requirements": [
                        {
                            "requirement_type": "comparison",
                            "expected_value": "exceeds the size of the bore of the MRI scanner"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Unable or unwilling to provide informed consent.",
            "criterions": [
                {
                    "exact_snippets": "Unable ... to provide informed consent.",
                    "criterion": "ability to provide informed consent",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "unwilling to provide informed consent.",
                    "criterion": "willingness to provide informed consent",
                    "requirements": [
                        {
                            "requirement_type": "willingness",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Contraindications, as described in the volunteer consent form, to MR or US scanning such as but not limited to accidental or implanted ferrous metal and/or implanted devices whose function can be disturbed by the main magnetic field, gradient magnetic fields, or radiofrequency energy.",
            "criterions": [
                {
                    "exact_snippets": "Contraindications, as described in the volunteer consent form, to MR or US scanning",
                    "criterion": "contraindications to MR or US scanning",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "accidental or implanted ferrous metal",
                    "criterion": "accidental or implanted ferrous metal",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "implanted devices whose function can be disturbed by the main magnetic field, gradient magnetic fields, or radiofrequency energy",
                    "criterion": "implanted devices affected by magnetic fields or radiofrequency energy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Women who are pregnant, suspect they might be pregnant or breastfeeding.",
            "criterions": [
                {
                    "exact_snippets": "Women who are pregnant",
                    "criterion": "pregnancy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "suspect they might be pregnant",
                    "criterion": "suspected pregnancy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "breastfeeding",
                    "criterion": "breastfeeding",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        }
    ],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": [
        {
            "line": "Inclusion Criteria (Patients):",
            "criterions": []
        },
        {
            "line": "Exclusion Criteria (All):",
            "criterions": []
        }
    ]
}