{
    "info": {
        "nct_id": "NCT03091231",
        "official_title": "Multiparametric Ultrasound - Contrast Enhanced Ultrasound and Shear Wave Elastography Compared to Radical Prostatectomy Specimens in 50 Patients",
        "inclusion_criteria": "* age ≥ 18 years\n* signed informed consent\nMust be MALE\nMust have minimum age of 18 Years\nMust have maximum age of 75 Years",
        "exclusion_criteria": "* History of any clinically evidence of cardiac right-to-left shunts\n* Receives treatment that includes dobutamine\n* Severe pulmonary hypertension (pulmonary artery pressure >90 mmHg) or uncontrolled systemic hypertension or respiratory distress syndrome\n* Has any medical condition or other circumstances which would significantly decrease the chances of obtaining reliable data, achieving study objectives, or completing the study\n* Is incapable of understanding the language in which the information for the patient is given",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* age ≥ 18 years",
            "criterions": [
                {
                    "exact_snippets": "age ≥ 18 years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* signed informed consent",
            "criterions": [
                {
                    "exact_snippets": "signed informed consent",
                    "criterion": "informed consent",
                    "requirements": [
                        {
                            "requirement_type": "signed",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must be MALE",
            "criterions": [
                {
                    "exact_snippets": "Must be MALE",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "expected_value",
                            "expected_value": "male"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 75 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 75 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 75,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* History of any clinically evidence of cardiac right-to-left shunts",
            "criterions": [
                {
                    "exact_snippets": "History of any clinically evidence of cardiac right-to-left shunts",
                    "criterion": "cardiac right-to-left shunts",
                    "requirements": [
                        {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Receives treatment that includes dobutamine",
            "criterions": [
                {
                    "exact_snippets": "Receives treatment that includes dobutamine",
                    "criterion": "treatment",
                    "requirements": [
                        {
                            "requirement_type": "inclusion",
                            "expected_value": "dobutamine"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Severe pulmonary hypertension (pulmonary artery pressure >90 mmHg) or uncontrolled systemic hypertension or respiratory distress syndrome",
            "criterions": [
                {
                    "exact_snippets": "Severe pulmonary hypertension (pulmonary artery pressure >90 mmHg)",
                    "criterion": "pulmonary hypertension",
                    "requirements": [
                        {
                            "requirement_type": "severity",
                            "expected_value": "severe"
                        },
                        {
                            "requirement_type": "pulmonary artery pressure",
                            "expected_value": {
                                "operator": ">",
                                "value": 90,
                                "unit": "mmHg"
                            }
                        }
                    ]
                },
                {
                    "exact_snippets": "uncontrolled systemic hypertension",
                    "criterion": "systemic hypertension",
                    "requirements": [
                        {
                            "requirement_type": "control",
                            "expected_value": "uncontrolled"
                        }
                    ]
                },
                {
                    "exact_snippets": "respiratory distress syndrome",
                    "criterion": "respiratory distress syndrome",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Has any medical condition or other circumstances which would significantly decrease the chances of obtaining reliable data, achieving study objectives, or completing the study",
            "criterions": [
                {
                    "exact_snippets": "Has any medical condition or other circumstances which would significantly decrease the chances of obtaining reliable data",
                    "criterion": "medical condition or other circumstances",
                    "requirements": [
                        {
                            "requirement_type": "impact on data reliability",
                            "expected_value": "significantly decrease"
                        }
                    ]
                },
                {
                    "exact_snippets": "Has any medical condition or other circumstances which would significantly decrease the chances of ... achieving study objectives",
                    "criterion": "medical condition or other circumstances",
                    "requirements": [
                        {
                            "requirement_type": "impact on study objectives",
                            "expected_value": "significantly decrease"
                        }
                    ]
                },
                {
                    "exact_snippets": "Has any medical condition or other circumstances which would significantly decrease the chances of ... completing the study",
                    "criterion": "medical condition or other circumstances",
                    "requirements": [
                        {
                            "requirement_type": "impact on study completion",
                            "expected_value": "significantly decrease"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Is incapable of understanding the language in which the information for the patient is given",
            "criterions": [
                {
                    "exact_snippets": "incapable of understanding the language",
                    "criterion": "language comprehension",
                    "requirements": [
                        {
                            "requirement_type": "capability",
                            "expected_value": false
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}