{
    "info": {
        "nct_id": "NCT03068520",
        "official_title": "Imaging After Stereotactic Radiosurgery for Brain Metastases or Primary Tumor Can Hybrid PET-MRI Differentiate Between Radiation Effects and Disease ?",
        "inclusion_criteria": "* Subject with glial brain tumors,\n* Subjects with metastatic brain tumors that were treated with stereotactic radiation (SRS), * Subjects with metastatic brain tumors which were not treated\nHealthy volunteers allowed\nMust have minimum age of 18 Years\nMust have maximum age of 70 Years",
        "exclusion_criteria": "* glial tumor with no histological diagnosis\n* non breast of lung metastasis\n* non compliance\n* unable to lay still during the scanning\n* mri non\n* renal failure/gadolinium sensitivity\n* less than 5 mm metastatic tumors\n* bleeding brain tumors\n* pregnancy",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Subject with glial brain tumors,",
            "criterions": [
                {
                    "exact_snippets": "glial brain tumors",
                    "criterion": "glial brain tumors",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Subjects with metastatic brain tumors that were treated with stereotactic radiation (SRS), * Subjects with metastatic brain tumors which were not treated",
            "criterions": [
                {
                    "exact_snippets": "Subjects with metastatic brain tumors",
                    "criterion": "metastatic brain tumors",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "treated with stereotactic radiation (SRS)",
                    "criterion": "stereotactic radiation (SRS) treatment",
                    "requirements": [
                        {
                            "requirement_type": "treatment status",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "Subjects with metastatic brain tumors which were not treated",
                    "criterion": "treatment status for metastatic brain tumors",
                    "requirements": [
                        {
                            "requirement_type": "treatment status",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 70 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 70 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 70,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* glial tumor with no histological diagnosis",
            "criterions": [
                {
                    "exact_snippets": "glial tumor",
                    "criterion": "glial tumor",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "no histological diagnosis",
                    "criterion": "histological diagnosis",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* non breast of lung metastasis",
            "criterions": [
                {
                    "exact_snippets": "non breast of lung metastasis",
                    "criterion": "metastasis",
                    "requirements": [
                        {
                            "requirement_type": "location",
                            "expected_value": [
                                "not breast",
                                "lung"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* non compliance",
            "criterions": [
                {
                    "exact_snippets": "non compliance",
                    "criterion": "compliance",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* unable to lay still during the scanning",
            "criterions": [
                {
                    "exact_snippets": "unable to lay still during the scanning",
                    "criterion": "ability to lay still during scanning",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* mri non",
            "criterions": [
                {
                    "exact_snippets": "mri non",
                    "criterion": "MRI",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* renal failure/gadolinium sensitivity",
            "criterions": [
                {
                    "exact_snippets": "renal failure",
                    "criterion": "renal failure",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "gadolinium sensitivity",
                    "criterion": "gadolinium sensitivity",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* less than 5 mm metastatic tumors",
            "criterions": [
                {
                    "exact_snippets": "less than 5 mm metastatic tumors",
                    "criterion": "metastatic tumors",
                    "requirements": [
                        {
                            "requirement_type": "size",
                            "expected_value": {
                                "operator": "<",
                                "value": 5,
                                "unit": "mm"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* bleeding brain tumors",
            "criterions": [
                {
                    "exact_snippets": "bleeding brain tumors",
                    "criterion": "brain tumors",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        },
                        {
                            "requirement_type": "bleeding",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* pregnancy",
            "criterions": [
                {
                    "exact_snippets": "pregnancy",
                    "criterion": "pregnancy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}