{
    "info": {
        "nct_id": "NCT02965391",
        "official_title": "Dynamic Changes and Surveillance of Circulating Tumor DNA in Surgical Non-small Cell Lung Cancer Patients",
        "inclusion_criteria": "* Suspected lung cancer before surgery\n* No malignant tumor history within the past 5 years\n* The pulmonary nodule is not pure ground glass opacity\n* Patients must have given written informed consent\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Multiple primary lung cancer\n* R1,R2 resection\n* Histology confirmed not non-small cell lung cancer\n* Unqualified blood samples",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Suspected lung cancer before surgery",
            "criterions": [
                {
                    "exact_snippets": "Suspected lung cancer",
                    "criterion": "lung cancer",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "before surgery",
                    "criterion": "surgery",
                    "requirements": [
                        {
                            "requirement_type": "timing",
                            "expected_value": "before"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* No malignant tumor history within the past 5 years",
            "criterions": [
                {
                    "exact_snippets": "No malignant tumor history within the past 5 years",
                    "criterion": "malignant tumor history",
                    "requirements": [
                        {
                            "requirement_type": "time since last occurrence",
                            "expected_value": {
                                "operator": ">=",
                                "value": 5,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* The pulmonary nodule is not pure ground glass opacity",
            "criterions": [
                {
                    "exact_snippets": "The pulmonary nodule is not pure ground glass opacity",
                    "criterion": "pulmonary nodule",
                    "requirements": [
                        {
                            "requirement_type": "composition",
                            "expected_value": "not pure ground glass opacity"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients must have given written informed consent",
            "criterions": [
                {
                    "exact_snippets": "Patients must have given written informed consent",
                    "criterion": "informed consent",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Multiple primary lung cancer",
            "criterions": [
                {
                    "exact_snippets": "Multiple primary lung cancer",
                    "criterion": "primary lung cancer",
                    "requirements": [
                        {
                            "requirement_type": "quantity",
                            "expected_value": "multiple"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* R1,R2 resection",
            "criterions": [
                {
                    "exact_snippets": "R1,R2 resection",
                    "criterion": "resection",
                    "requirements": [
                        {
                            "requirement_type": "type",
                            "expected_value": [
                                "R1",
                                "R2"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Histology confirmed not non-small cell lung cancer",
            "criterions": [
                {
                    "exact_snippets": "Histology confirmed not non-small cell lung cancer",
                    "criterion": "non-small cell lung cancer",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Unqualified blood samples",
            "criterions": [
                {
                    "exact_snippets": "Unqualified blood samples",
                    "criterion": "blood samples",
                    "requirements": [
                        {
                            "requirement_type": "qualification",
                            "expected_value": false
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}