{
    "info": {
        "nct_id": "NCT02965001",
        "official_title": "Phase II Trial: uPAR-PET/CT for Prognostication in Head- and Neck Cancer",
        "inclusion_criteria": "The patient\n\n* has a diagnosis of biopsy-verified cancer of the pharynx, larynx or oral cavity\n* is referred to curative intended radiotherapy\n* understands the given information and has given informed consent and\n* age above 18 years.\nHealthy volunteers allowed\nMust have minimum age of 18 Years\nMust have maximum age of 85 Years",
        "exclusion_criteria": "Pregnancy, lactation/breast feeding, age above 85 years, obesity (bodyweight above 140 kg), small cancers of the larynx (1A,1B), allergy to 68Ga-NOTA-AE105, metastasis on FDG-PET/CT, other previously known cancers, claustrophobia.\n\n-",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* has a diagnosis of biopsy-verified cancer of the pharynx, larynx or oral cavity",
            "criterions": [
                {
                    "exact_snippets": "diagnosis of biopsy-verified cancer",
                    "criterion": "cancer diagnosis",
                    "requirements": [
                        {
                            "requirement_type": "verification",
                            "expected_value": "biopsy"
                        }
                    ]
                },
                {
                    "exact_snippets": "cancer of the pharynx, larynx or oral cavity",
                    "criterion": "cancer location",
                    "requirements": [
                        {
                            "requirement_type": "location",
                            "expected_value": [
                                "pharynx",
                                "larynx",
                                "oral cavity"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* is referred to curative intended radiotherapy",
            "criterions": [
                {
                    "exact_snippets": "referred to curative intended radiotherapy",
                    "criterion": "curative intended radiotherapy",
                    "requirements": [
                        {
                            "requirement_type": "referral",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* understands the given information and has given informed consent and",
            "criterions": [
                {
                    "exact_snippets": "understands the given information",
                    "criterion": "understanding of information",
                    "requirements": [
                        {
                            "requirement_type": "comprehension",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "has given informed consent",
                    "criterion": "informed consent",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* age above 18 years.",
            "criterions": [
                {
                    "exact_snippets": "age above 18 years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 85 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 85 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 85,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "Pregnancy, lactation/breast feeding, age above 85 years, obesity (bodyweight above 140 kg), small cancers of the larynx (1A,1B), allergy to 68Ga-NOTA-AE105, metastasis on FDG-PET/CT, other previously known cancers, claustrophobia.",
            "criterions": [
                {
                    "exact_snippets": "Pregnancy",
                    "criterion": "pregnancy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "lactation/breast feeding",
                    "criterion": "lactation",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "age above 85 years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">",
                                "value": 85,
                                "unit": "years"
                            }
                        }
                    ]
                },
                {
                    "exact_snippets": "obesity (bodyweight above 140 kg)",
                    "criterion": "obesity",
                    "requirements": [
                        {
                            "requirement_type": "bodyweight",
                            "expected_value": {
                                "operator": ">",
                                "value": 140,
                                "unit": "kg"
                            }
                        }
                    ]
                },
                {
                    "exact_snippets": "small cancers of the larynx (1A,1B)",
                    "criterion": "small cancers of the larynx",
                    "requirements": [
                        {
                            "requirement_type": "stage",
                            "expected_value": [
                                "1A",
                                "1B"
                            ]
                        }
                    ]
                },
                {
                    "exact_snippets": "allergy to 68Ga-NOTA-AE105",
                    "criterion": "allergy to 68Ga-NOTA-AE105",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "metastasis on FDG-PET/CT",
                    "criterion": "metastasis on FDG-PET/CT",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "other previously known cancers",
                    "criterion": "other previously known cancers",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "claustrophobia",
                    "criterion": "claustrophobia",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [
        {
            "line": "The patient",
            "criterions": []
        }
    ],
    "failed_exclusion": [
        {
            "line": "-",
            "criterions": []
        }
    ],
    "failed_miscellaneous": []
}