{
    "info": {
        "nct_id": "NCT02727673",
        "official_title": "A Prospective Randomized Trial on the Relationship Between Circulating Tumor Stem Cells and the Clinical Pathology",
        "inclusion_criteria": "1. Male or female patients > 18 years and <=70 years of age;\n2. No dysfunction in major organs; Blood routine, kidney function, cardiac function and lung function are basically normal.\n3. Patients who can understand this trial and have signed information consent\nHealthy volunteers allowed\nMust have minimum age of 18 Years\nMust have maximum age of 70 Years",
        "exclusion_criteria": "1. Reject to attend；\n2. Impossible to come to our hospital for physical examination regularly;\n3. Patients with other diseases which may affect the treatment mentioned",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "1. Male or female patients > 18 years and <=70 years of age;",
            "criterions": [
                {
                    "exact_snippets": "Male or female patients",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": [
                                "male",
                                "female"
                            ]
                        }
                    ]
                },
                {
                    "exact_snippets": "patients > 18 years and <=70 years of age",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">",
                                        "value": 18,
                                        "unit": "years"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 70,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "2. No dysfunction in major organs; Blood routine, kidney function, cardiac function and lung function are basically normal.",
            "criterions": [
                {
                    "exact_snippets": "No dysfunction in major organs",
                    "criterion": "major organ dysfunction",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "Blood routine ... are basically normal",
                    "criterion": "blood routine",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "basically normal"
                        }
                    ]
                },
                {
                    "exact_snippets": "kidney function ... are basically normal",
                    "criterion": "kidney function",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "basically normal"
                        }
                    ]
                },
                {
                    "exact_snippets": "cardiac function ... are basically normal",
                    "criterion": "cardiac function",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "basically normal"
                        }
                    ]
                },
                {
                    "exact_snippets": "lung function are basically normal",
                    "criterion": "lung function",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "basically normal"
                        }
                    ]
                }
            ]
        },
        {
            "line": "3. Patients who can understand this trial and have signed information consent",
            "criterions": [
                {
                    "exact_snippets": "Patients who can understand this trial",
                    "criterion": "understanding of the trial",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "have signed information consent",
                    "criterion": "signed informed consent",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 70 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 70 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 70,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "1. Reject to attend；",
            "criterions": [
                {
                    "exact_snippets": "Reject to attend",
                    "criterion": "willingness to attend",
                    "requirements": [
                        {
                            "requirement_type": "willingness",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "2. Impossible to come to our hospital for physical examination regularly;",
            "criterions": [
                {
                    "exact_snippets": "Impossible to come to our hospital for physical examination regularly",
                    "criterion": "ability to attend regular physical examinations",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "3. Patients with other diseases which may affect the treatment mentioned",
            "criterions": [
                {
                    "exact_snippets": "Patients with other diseases which may affect the treatment",
                    "criterion": "other diseases",
                    "requirements": [
                        {
                            "requirement_type": "impact on treatment",
                            "expected_value": "may affect"
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}