{
    "info": {
        "nct_id": "NCT02562729",
        "official_title": "A Simplified Approach of Complete Nerve-sparing Type C1 Radical Hysterectomy for Cervical Cancer, a Phase II Study",
        "inclusion_criteria": "* Age >=18 years to <= 70 years.\n* Women with histologically confirmed, primary adenocarcinoma or squamous cell carcinoma of the uterine cervix.\n* Stage IIA1, or IB1 disease.\n* Karnofsky performance status >70.\n* Patients who comply with follow-up.\n* With written informed consent.\nHealthy volunteers allowed\nMust be FEMALE\nMust have minimum age of 18 Years\nMust have maximum age of 70 Years",
        "exclusion_criteria": "* Age>70\n* History of lower urinary tract damage or surgery.\n* With abnormal urodynamic study results.\n* Karnofsky performance status <70.\n* Patients who have uncontrolled psychological disorders.\n* Unwilling to or unable to comply with protocol.\n* Prior treatment with pelvic radiotherapy",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Age >=18 years to <= 70 years.",
            "criterions": [
                {
                    "exact_snippets": "Age >=18 years to <= 70 years.",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 18,
                                        "unit": "years"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 70,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Women with histologically confirmed, primary adenocarcinoma or squamous cell carcinoma of the uterine cervix.",
            "criterions": [
                {
                    "exact_snippets": "Women",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "expected gender",
                            "expected_value": "female"
                        }
                    ]
                },
                {
                    "exact_snippets": "histologically confirmed",
                    "criterion": "histological confirmation",
                    "requirements": [
                        {
                            "requirement_type": "confirmation",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "primary adenocarcinoma or squamous cell carcinoma",
                    "criterion": "cancer type",
                    "requirements": [
                        {
                            "requirement_type": "type",
                            "expected_value": [
                                "adenocarcinoma",
                                "squamous cell carcinoma"
                            ]
                        }
                    ]
                },
                {
                    "exact_snippets": "of the uterine cervix",
                    "criterion": "cancer location",
                    "requirements": [
                        {
                            "requirement_type": "location",
                            "expected_value": "uterine cervix"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Stage IIA1, or IB1 disease.",
            "criterions": [
                {
                    "exact_snippets": "Stage IIA1, or IB1 disease",
                    "criterion": "cancer stage",
                    "requirements": [
                        {
                            "requirement_type": "specific stages",
                            "expected_value": [
                                "IIA1",
                                "IB1"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Karnofsky performance status >70.",
            "criterions": [
                {
                    "exact_snippets": "Karnofsky performance status >70",
                    "criterion": "Karnofsky performance status",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">",
                                "value": 70,
                                "unit": "N/A"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients who comply with follow-up.",
            "criterions": [
                {
                    "exact_snippets": "Patients who comply with follow-up.",
                    "criterion": "follow-up compliance",
                    "requirements": [
                        {
                            "requirement_type": "compliance",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* With written informed consent.",
            "criterions": [
                {
                    "exact_snippets": "written informed consent",
                    "criterion": "informed consent",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must be FEMALE",
            "criterions": [
                {
                    "exact_snippets": "Must be FEMALE",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "N/A",
                            "expected_value": "female"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 70 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 70 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 70,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Age>70",
            "criterions": [
                {
                    "exact_snippets": "Age>70",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">",
                                "value": 70,
                                "unit": "N/A"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* History of lower urinary tract damage or surgery.",
            "criterions": [
                {
                    "exact_snippets": "History of lower urinary tract damage",
                    "criterion": "lower urinary tract damage",
                    "requirements": [
                        {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "History of ... surgery",
                    "criterion": "surgery",
                    "requirements": [
                        {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* With abnormal urodynamic study results.",
            "criterions": [
                {
                    "exact_snippets": "abnormal urodynamic study results",
                    "criterion": "urodynamic study results",
                    "requirements": [
                        {
                            "requirement_type": "normality",
                            "expected_value": "abnormal"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Karnofsky performance status <70.",
            "criterions": [
                {
                    "exact_snippets": "Karnofsky performance status <70",
                    "criterion": "Karnofsky performance status",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": "<",
                                "value": 70,
                                "unit": "N/A"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients who have uncontrolled psychological disorders.",
            "criterions": [
                {
                    "exact_snippets": "uncontrolled psychological disorders",
                    "criterion": "psychological disorders",
                    "requirements": [
                        {
                            "requirement_type": "control",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Unwilling to or unable to comply with protocol.",
            "criterions": [
                {
                    "exact_snippets": "Unwilling to or unable to comply with protocol.",
                    "criterion": "compliance with protocol",
                    "requirements": [
                        {
                            "requirement_type": "willingness",
                            "expected_value": true
                        },
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Prior treatment with pelvic radiotherapy",
            "criterions": [
                {
                    "exact_snippets": "Prior treatment with pelvic radiotherapy",
                    "criterion": "pelvic radiotherapy",
                    "requirements": [
                        {
                            "requirement_type": "prior treatment",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}