{
    "info": {
        "nct_id": "NCT02426762",
        "official_title": "Use of a Quick Skin Sealant in Prevention of Surgical Site Infection After Laparoscopic Tumor Resection",
        "inclusion_criteria": "* The informed consent has been obtained from the patient.\n* With confirmed diagnosis of gastric cancer, colorectal cancer, gastrointestinal stromal tumor, inflammatory bowel disease and diverticula.\n* Endurable laparoscopic surgery without conversion.\n* With moderate/good ECOG health rating (PS): 0-1 score.\nHealthy volunteers allowed\nMust have minimum age of 16 Years\nMust have maximum age of 65 Years",
        "exclusion_criteria": "* Pregnant woman or lactating woman.\n* With confirmed distant metastasis in liver, lung, bones, or other organs.\n* Intolerable laparoscopic operation or converted to open surgery.\n* With severe comorbidities, such as cardiovascular disease, chronic obstructive pulmonary disease, diabetes mellitus, and chronic renal dysfunction.\n* With bad compliance or contraindication to enrollment.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* The informed consent has been obtained from the patient.",
            "criterions": [
                {
                    "exact_snippets": "informed consent has been obtained",
                    "criterion": "informed consent",
                    "requirements": [
                        {
                            "requirement_type": "obtained",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Endurable laparoscopic surgery without conversion.",
            "criterions": [
                {
                    "exact_snippets": "Endurable laparoscopic surgery without conversion.",
                    "criterion": "laparoscopic surgery",
                    "requirements": [
                        {
                            "requirement_type": "endurance",
                            "expected_value": true
                        },
                        {
                            "requirement_type": "conversion",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* With moderate/good ECOG health rating (PS): 0-1 score.",
            "criterions": [
                {
                    "exact_snippets": "ECOG health rating (PS): 0-1 score",
                    "criterion": "ECOG performance status",
                    "requirements": [
                        {
                            "requirement_type": "score",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 0,
                                        "unit": "score"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 1,
                                        "unit": "score"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 16 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 16 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 16,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 65 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 65 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 65,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Pregnant woman or lactating woman.",
            "criterions": [
                {
                    "exact_snippets": "Pregnant woman",
                    "criterion": "pregnancy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "lactating woman",
                    "criterion": "lactation",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Intolerable laparoscopic operation or converted to open surgery.",
            "criterions": [
                {
                    "exact_snippets": "Intolerable laparoscopic operation",
                    "criterion": "laparoscopic operation",
                    "requirements": [
                        {
                            "requirement_type": "tolerance",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "converted to open surgery",
                    "criterion": "conversion to open surgery",
                    "requirements": [
                        {
                            "requirement_type": "occurrence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* With severe comorbidities, such as cardiovascular disease, chronic obstructive pulmonary disease, diabetes mellitus, and chronic renal dysfunction.",
            "criterions": [
                {
                    "exact_snippets": "severe comorbidities, such as cardiovascular disease",
                    "criterion": "cardiovascular disease",
                    "requirements": [
                        {
                            "requirement_type": "severity",
                            "expected_value": "severe"
                        }
                    ]
                },
                {
                    "exact_snippets": "severe comorbidities, such as ... chronic obstructive pulmonary disease",
                    "criterion": "chronic obstructive pulmonary disease",
                    "requirements": [
                        {
                            "requirement_type": "severity",
                            "expected_value": "severe"
                        }
                    ]
                },
                {
                    "exact_snippets": "severe comorbidities, such as ... diabetes mellitus",
                    "criterion": "diabetes mellitus",
                    "requirements": [
                        {
                            "requirement_type": "severity",
                            "expected_value": "severe"
                        }
                    ]
                },
                {
                    "exact_snippets": "severe comorbidities, such as ... chronic renal dysfunction",
                    "criterion": "chronic renal dysfunction",
                    "requirements": [
                        {
                            "requirement_type": "severity",
                            "expected_value": "severe"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* With bad compliance or contraindication to enrollment.",
            "criterions": [
                {
                    "exact_snippets": "bad compliance",
                    "criterion": "compliance",
                    "requirements": [
                        {
                            "requirement_type": "quality",
                            "expected_value": "good"
                        }
                    ]
                },
                {
                    "exact_snippets": "contraindication to enrollment",
                    "criterion": "contraindication to enrollment",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [
        {
            "line": "* With confirmed diagnosis of gastric cancer, colorectal cancer, gastrointestinal stromal tumor, inflammatory bowel disease and diverticula.",
            "criterions": [
                {
                    "exact_snippets": "confirmed diagnosis of gastric cancer",
                    "criterion": "gastric cancer",
                    "requirements": [
                        {
                            "requirement_type": "diagnosis",
                            "expected_value": "confirmed"
                        }
                    ]
                },
                {
                    "exact_snippets": "confirmed diagnosis of colorectal cancer",
                    "criterion": "colorectal cancer",
                    "requirements": [
                        {
                            "requirement_type": "diagnosis",
                            "expected_value": "confirmed"
                        }
                    ]
                },
                {
                    "exact_snippets": "confirmed diagnosis of gastrointestinal stromal tumor",
                    "criterion": "gastrointestinal stromal tumor",
                    "requirements": [
                        {
                            "requirement_type": "diagnosis",
                            "expected_value": "confirmed"
                        }
                    ]
                },
                {
                    "exact_snippets": "confirmed diagnosis of inflammatory bowel disease",
                    "criterion": "inflammatory bowel disease",
                    "requirements": [
                        {
                            "requirement_type": "diagnosis",
                            "expected_value": "confirmed"
                        }
                    ]
                },
                {
                    "exact_snippets": "confirmed diagnosis of diverticula",
                    "criterion": "diverticula",
                    "requirements": [
                        {
                            "requirement_type": "diagnosis",
                            "expected_value": "confirmed"
                        }
                    ]
                }
            ]
        }
    ],
    "failed_exclusion": [
        {
            "line": "* With confirmed distant metastasis in liver, lung, bones, or other organs.",
            "criterions": [
                {
                    "exact_snippets": "confirmed distant metastasis in liver",
                    "criterion": "distant metastasis in liver",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "confirmed distant metastasis in lung",
                    "criterion": "distant metastasis in lung",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "confirmed distant metastasis in bones",
                    "criterion": "distant metastasis in bones",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "confirmed distant metastasis in ... other organs",
                    "criterion": "distant metastasis in other organs",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "failed_miscellaneous": []
}