{
    "info": {
        "nct_id": "NCT01674582",
        "official_title": "Treatment Effects Inclusive Cognitive Impact and Possibilities to Individually Adjusted Treatment in Patients With Intracranial Tumors With Clinical, Neuropsychological and Imaging Parameters.",
        "inclusion_criteria": "* Age 18 years or older\n* Suspected primary brain tumor, verified glioblastoma or non surgically treated metastases from solid tumor\n* Increasing MRI changes in patients with previous verified glioblastoma\n* Be able to speak Swedish without difficulties (because of the neuropsychological investigations)\n* Written informed concent\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Unability to perform MRI",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Age 18 years or older",
            "criterions": [
                {
                    "exact_snippets": "Age 18 years or older",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Suspected primary brain tumor, verified glioblastoma or non surgically treated metastases from solid tumor",
            "criterions": [
                {
                    "exact_snippets": "Suspected primary brain tumor",
                    "criterion": "primary brain tumor",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "verified glioblastoma",
                    "criterion": "glioblastoma",
                    "requirements": [
                        {
                            "requirement_type": "verification",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "non surgically treated metastases from solid tumor",
                    "criterion": "metastases from solid tumor",
                    "requirements": [
                        {
                            "requirement_type": "treatment",
                            "expected_value": "non surgically treated"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Increasing MRI changes in patients with previous verified glioblastoma",
            "criterions": [
                {
                    "exact_snippets": "Increasing MRI changes",
                    "criterion": "MRI changes",
                    "requirements": [
                        {
                            "requirement_type": "trend",
                            "expected_value": "increasing"
                        }
                    ]
                },
                {
                    "exact_snippets": "previous verified glioblastoma",
                    "criterion": "glioblastoma",
                    "requirements": [
                        {
                            "requirement_type": "verification",
                            "expected_value": true
                        },
                        {
                            "requirement_type": "temporal",
                            "expected_value": "previous"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Be able to speak Swedish without difficulties (because of the neuropsychological investigations)",
            "criterions": [
                {
                    "exact_snippets": "speak Swedish without difficulties",
                    "criterion": "Swedish language proficiency",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Unability to perform MRI",
            "criterions": [
                {
                    "exact_snippets": "Unability to perform MRI",
                    "criterion": "MRI",
                    "requirements": [
                        {
                            "requirement_type": "ability to perform",
                            "expected_value": false
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [
        {
            "line": "* Written informed concent",
            "criterions": [
                {
                    "exact_snippets": "Written informed consent",
                    "criterion": "informed consent",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}