{
    "info": {
        "nct_id": "NCT00937560",
        "official_title": "A Single-arm Phase II Clinical Study Investigating the Addition of Bevacizumab to Carboplatin and Weekly Paclitaxel as First-line Treatment in Patients With Epithelial Ovarian Cancer",
        "inclusion_criteria": "Healthy volunteers allowed\nMust be FEMALE\nMust have minimum age of 18 Years",
        "exclusion_criteria": "",
        "miscellaneous_criteria": "Inclusion Criteria\n\n* Female patients, ≥ 18 years of age.\n* Epithelial ovarian, fallopian tube, or primary peritoneal cancer.\n* Initial surgery, but no chemotherapy or radiotherapy.\n* Eastern Cooperative Oncology Group (ECOG) performance status of 0-2.\n\nExclusion Criteria\n\n* Non-epithelial tumors.\n* Ovarian tumors with low malignant potential.\n* Previous systemic anti-cancer therapy for ovarian cancer.\n* History or evidence of synchronous primary endometrial cancer.\n* Current or recent daily treatment with aspirin (> 325mg/day) or with full dose anticoagulant or thrombolytic agents for therapeutic purposes."
    },
    "inclusion_lines": [
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must be FEMALE",
            "criterions": [
                {
                    "exact_snippets": "Must be FEMALE",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "expected_value",
                            "expected_value": "female"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [],
    "miscellaneous_lines": [
        {
            "line": "* Female patients, ≥ 18 years of age.",
            "criterions": [
                {
                    "exact_snippets": "Female patients",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": "female"
                        }
                    ]
                },
                {
                    "exact_snippets": "≥ 18 years of age",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Epithelial ovarian, fallopian tube, or primary peritoneal cancer.",
            "criterions": [
                {
                    "exact_snippets": "Epithelial ovarian",
                    "criterion": "epithelial ovarian cancer",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "fallopian tube",
                    "criterion": "fallopian tube cancer",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "primary peritoneal cancer",
                    "criterion": "primary peritoneal cancer",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Initial surgery, but no chemotherapy or radiotherapy.",
            "criterions": [
                {
                    "exact_snippets": "Initial surgery",
                    "criterion": "surgery",
                    "requirements": [
                        {
                            "requirement_type": "type",
                            "expected_value": "initial"
                        }
                    ]
                },
                {
                    "exact_snippets": "no chemotherapy",
                    "criterion": "chemotherapy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "no ... radiotherapy",
                    "criterion": "radiotherapy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Eastern Cooperative Oncology Group (ECOG) performance status of 0-2.",
            "criterions": [
                {
                    "exact_snippets": "Eastern Cooperative Oncology Group (ECOG) performance status of 0-2.",
                    "criterion": "ECOG performance status",
                    "requirements": [
                        {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 0,
                                        "unit": "N/A"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 2,
                                        "unit": "N/A"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Non-epithelial tumors.",
            "criterions": [
                {
                    "exact_snippets": "Non-epithelial tumors.",
                    "criterion": "tumor type",
                    "requirements": [
                        {
                            "requirement_type": "type",
                            "expected_value": "non-epithelial"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Ovarian tumors with low malignant potential.",
            "criterions": [
                {
                    "exact_snippets": "Ovarian tumors",
                    "criterion": "ovarian tumors",
                    "requirements": [
                        {
                            "requirement_type": "malignant potential",
                            "expected_value": "low"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Previous systemic anti-cancer therapy for ovarian cancer.",
            "criterions": [
                {
                    "exact_snippets": "Previous systemic anti-cancer therapy for ovarian cancer.",
                    "criterion": "systemic anti-cancer therapy",
                    "requirements": [
                        {
                            "requirement_type": "previous treatment",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* History or evidence of synchronous primary endometrial cancer.",
            "criterions": [
                {
                    "exact_snippets": "History or evidence of synchronous primary endometrial cancer.",
                    "criterion": "synchronous primary endometrial cancer",
                    "requirements": [
                        {
                            "requirement_type": "history or evidence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Current or recent daily treatment with aspirin (> 325mg/day) or with full dose anticoagulant or thrombolytic agents for therapeutic purposes.",
            "criterions": [
                {
                    "exact_snippets": "Current or recent daily treatment with aspirin (> 325mg/day)",
                    "criterion": "aspirin treatment",
                    "requirements": [
                        {
                            "requirement_type": "dosage",
                            "expected_value": {
                                "operator": ">",
                                "value": 325,
                                "unit": "mg/day"
                            }
                        }
                    ]
                },
                {
                    "exact_snippets": "Current or recent daily treatment ... with full dose anticoagulant",
                    "criterion": "anticoagulant treatment",
                    "requirements": [
                        {
                            "requirement_type": "dosage",
                            "expected_value": "full dose"
                        }
                    ]
                },
                {
                    "exact_snippets": "Current or recent daily treatment ... with ... thrombolytic agents for therapeutic purposes",
                    "criterion": "thrombolytic agent treatment",
                    "requirements": [
                        {
                            "requirement_type": "purpose",
                            "expected_value": "therapeutic"
                        }
                    ]
                }
            ]
        }
    ],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": [
        {
            "line": "Inclusion Criteria",
            "criterions": []
        },
        {
            "line": "Exclusion Criteria",
            "criterions": []
        }
    ]
}