{
    "info": {
        "nct_id": "NCT00801320",
        "official_title": "Study of Primary Tumor Harvest for the Purpose of Possible Use in a Future Clinical Trial in Patients With Ovarian, Fallopian Tube or Primary Peritoneal Cancer (Ovarian Spore)",
        "inclusion_criteria": "* Clinical suspicion of advanced ovarian, fallopian tube or primary peritoneal cancer as determined by a gynecologic oncologist\n* Patients are planning to undergo primary or secondary debulking surgery as part of standard of care for their disease\n* Estimated life expectancy of 6 months or greater\n* 18 years of age or older\nHealthy volunteers allowed\nMust be FEMALE\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* More than one prior chemotherapy regimen\n* Serious intercurrent illness such as infection requiring IV antibiotics, or significant cardiac disease characterized by significant arrhythmia, unstable ischemic coronary disease or congestive heart failure\n* Known HIV infection\n* Active second malignancy, aside from basal cell or squamous cell carcinoma of the skin\n* Significant autoimmune disease, including psoriasis\n* History of clinically significant venous thromboembolism",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Clinical suspicion of advanced ovarian, fallopian tube or primary peritoneal cancer as determined by a gynecologic oncologist",
            "criterions": [
                {
                    "exact_snippets": "Clinical suspicion of advanced ovarian, fallopian tube or primary peritoneal cancer",
                    "criterion": "advanced ovarian, fallopian tube or primary peritoneal cancer",
                    "requirements": [
                        {
                            "requirement_type": "suspicion",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "as determined by a gynecologic oncologist",
                    "criterion": "determination by a gynecologic oncologist",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients are planning to undergo primary or secondary debulking surgery as part of standard of care for their disease",
            "criterions": [
                {
                    "exact_snippets": "Patients are planning to undergo primary or secondary debulking surgery",
                    "criterion": "surgery type",
                    "requirements": [
                        {
                            "requirement_type": "planned",
                            "expected_value": [
                                "primary debulking surgery",
                                "secondary debulking surgery"
                            ]
                        }
                    ]
                },
                {
                    "exact_snippets": "as part of standard of care for their disease",
                    "criterion": "standard of care",
                    "requirements": [
                        {
                            "requirement_type": "inclusion",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Estimated life expectancy of 6 months or greater",
            "criterions": [
                {
                    "exact_snippets": "Estimated life expectancy of 6 months or greater",
                    "criterion": "life expectancy",
                    "requirements": [
                        {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": ">=",
                                "value": 6,
                                "unit": "months"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* 18 years of age or older",
            "criterions": [
                {
                    "exact_snippets": "18 years of age or older",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must be FEMALE",
            "criterions": [
                {
                    "exact_snippets": "Must be FEMALE",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "expected_value",
                            "expected_value": "female"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* More than one prior chemotherapy regimen",
            "criterions": [
                {
                    "exact_snippets": "More than one prior chemotherapy regimen",
                    "criterion": "prior chemotherapy regimens",
                    "requirements": [
                        {
                            "requirement_type": "quantity",
                            "expected_value": {
                                "operator": ">",
                                "value": 1,
                                "unit": "N/A"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Serious intercurrent illness such as infection requiring IV antibiotics, or significant cardiac disease characterized by significant arrhythmia, unstable ischemic coronary disease or congestive heart failure",
            "criterions": [
                {
                    "exact_snippets": "Serious intercurrent illness such as infection requiring IV antibiotics",
                    "criterion": "serious intercurrent illness",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "infection requiring IV antibiotics",
                    "criterion": "infection",
                    "requirements": [
                        {
                            "requirement_type": "treatment",
                            "expected_value": "IV antibiotics"
                        }
                    ]
                },
                {
                    "exact_snippets": "significant cardiac disease characterized by significant arrhythmia",
                    "criterion": "significant cardiac disease",
                    "requirements": [
                        {
                            "requirement_type": "characterization",
                            "expected_value": "significant arrhythmia"
                        }
                    ]
                },
                {
                    "exact_snippets": "significant cardiac disease characterized by ... unstable ischemic coronary disease",
                    "criterion": "significant cardiac disease",
                    "requirements": [
                        {
                            "requirement_type": "characterization",
                            "expected_value": "unstable ischemic coronary disease"
                        }
                    ]
                },
                {
                    "exact_snippets": "significant cardiac disease characterized by ... congestive heart failure",
                    "criterion": "significant cardiac disease",
                    "requirements": [
                        {
                            "requirement_type": "characterization",
                            "expected_value": "congestive heart failure"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Known HIV infection",
            "criterions": [
                {
                    "exact_snippets": "Known HIV infection",
                    "criterion": "HIV infection",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Active second malignancy, aside from basal cell or squamous cell carcinoma of the skin",
            "criterions": [
                {
                    "exact_snippets": "Active second malignancy",
                    "criterion": "second malignancy",
                    "requirements": [
                        {
                            "requirement_type": "activity",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "aside from basal cell or squamous cell carcinoma of the skin",
                    "criterion": "type of second malignancy",
                    "requirements": [
                        {
                            "requirement_type": "exclusion",
                            "expected_value": [
                                "basal cell carcinoma of the skin",
                                "squamous cell carcinoma of the skin"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Significant autoimmune disease, including psoriasis",
            "criterions": [
                {
                    "exact_snippets": "Significant autoimmune disease",
                    "criterion": "autoimmune disease",
                    "requirements": [
                        {
                            "requirement_type": "severity",
                            "expected_value": "significant"
                        }
                    ]
                },
                {
                    "exact_snippets": "including psoriasis",
                    "criterion": "psoriasis",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* History of clinically significant venous thromboembolism",
            "criterions": [
                {
                    "exact_snippets": "History of clinically significant venous thromboembolism",
                    "criterion": "venous thromboembolism",
                    "requirements": [
                        {
                            "requirement_type": "history",
                            "expected_value": true
                        },
                        {
                            "requirement_type": "clinical significance",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}