{
    "info": {
        "nct_id": "NCT00332748",
        "official_title": "Effect of Esomeprazole on the Pharmacokinetics of BMS-275183 in Patients With Advanced Malignancies",
        "inclusion_criteria": "* Advanced cancers excluding cancers within the blood\n* Adequate kidney and liver function\n* > = 4 weeks from last course of chemotherapy\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Inability to swallow capsules\n* Other active medical disorder\n* Abnormal heart function or use of drugs that affect the heart",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Advanced cancers excluding cancers within the blood",
            "criterions": [
                {
                    "exact_snippets": "Advanced cancers",
                    "criterion": "cancer stage",
                    "requirements": [
                        {
                            "requirement_type": "stage",
                            "expected_value": "advanced"
                        }
                    ]
                },
                {
                    "exact_snippets": "excluding cancers within the blood",
                    "criterion": "cancer type",
                    "requirements": [
                        {
                            "requirement_type": "exclusion",
                            "expected_value": "blood cancers"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Adequate kidney and liver function",
            "criterions": [
                {
                    "exact_snippets": "Adequate kidney ... function",
                    "criterion": "kidney function",
                    "requirements": [
                        {
                            "requirement_type": "adequacy",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "Adequate ... liver function",
                    "criterion": "liver function",
                    "requirements": [
                        {
                            "requirement_type": "adequacy",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* > = 4 weeks from last course of chemotherapy",
            "criterions": [
                {
                    "exact_snippets": "= 4 weeks from last course of chemotherapy",
                    "criterion": "time since last chemotherapy",
                    "requirements": [
                        {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": ">=",
                                "value": 4,
                                "unit": "weeks"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Inability to swallow capsules",
            "criterions": [
                {
                    "exact_snippets": "Inability to swallow capsules",
                    "criterion": "ability to swallow capsules",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Other active medical disorder",
            "criterions": [
                {
                    "exact_snippets": "Other active medical disorder",
                    "criterion": "active medical disorder",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Abnormal heart function or use of drugs that affect the heart",
            "criterions": [
                {
                    "exact_snippets": "Abnormal heart function",
                    "criterion": "heart function",
                    "requirements": [
                        {
                            "requirement_type": "condition",
                            "expected_value": "abnormal"
                        }
                    ]
                },
                {
                    "exact_snippets": "use of drugs that affect the heart",
                    "criterion": "use of drugs",
                    "requirements": [
                        {
                            "requirement_type": "effect",
                            "expected_value": "affect the heart"
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}