{
    "info": {
        "nct_id": "NCT00200382",
        "official_title": "Phase II Study to Evaluate the Efficacy and Safety of Therapy With PS 341 in Patients With Advanced Stage Non Small Cell Lung Cancer",
        "inclusion_criteria": "* Patients must have confirmed NSCLC (squamous, adeno- and large cell anaplastic carcinoma)stage III B or Stage IV.\n\nNo prior chemotherapy regimen Patients must have adequate organ and marrow function\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Untreated symptomatic brain metastasis Patients with known HIV positivity",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Patients must have confirmed NSCLC (squamous, adeno- and large cell anaplastic carcinoma)stage III B or Stage IV.",
            "criterions": [
                {
                    "exact_snippets": "confirmed NSCLC (squamous, adeno- and large cell anaplastic carcinoma)",
                    "criterion": "NSCLC subtype",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": [
                                "squamous",
                                "adeno-",
                                "large cell anaplastic carcinoma"
                            ]
                        }
                    ]
                },
                {
                    "exact_snippets": "stage III B or Stage IV",
                    "criterion": "cancer stage",
                    "requirements": [
                        {
                            "requirement_type": "stage",
                            "expected_value": [
                                "III B",
                                "IV"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "No prior chemotherapy regimen Patients must have adequate organ and marrow function",
            "criterions": [
                {
                    "exact_snippets": "No prior chemotherapy regimen",
                    "criterion": "prior chemotherapy regimen",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "adequate organ and marrow function",
                    "criterion": "organ and marrow function",
                    "requirements": [
                        {
                            "requirement_type": "adequacy",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Untreated symptomatic brain metastasis Patients with known HIV positivity",
            "criterions": [
                {
                    "exact_snippets": "Untreated symptomatic brain metastasis",
                    "criterion": "brain metastasis",
                    "requirements": [
                        {
                            "requirement_type": "treatment status",
                            "expected_value": "untreated"
                        },
                        {
                            "requirement_type": "symptom presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "Patients with known HIV positivity",
                    "criterion": "HIV status",
                    "requirements": [
                        {
                            "requirement_type": "positivity",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}