<?xml version="1.0" encoding="UTF-8"?><xmi:XMI xmlns:tcas="http:///uima/tcas.ecore" xmlns:xmi="http://www.omg.org/XMI" xmlns:cas="http:///uima/cas.ecore" xmlns:bmi="http:///edu/buffalo/bmi.ecore" xmi:version="2.0"><cas:NULL xmi:id="0"/><tcas:DocumentAnnotation xmi:id="8" sofa="1" begin="0" end="2332" language="x-unspecified"/><bmi:NNToken xmi:id="13" sofa="1" begin="0" end="14" Lemma="nci-2017-00135" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="69" sofa="1" begin="43" end="66" Lemma="screening/pre-screening" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="85" sofa="1" begin="71" end="80" Lemma="sub-study" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="93" sofa="1" begin="81" end="93" Lemma="registration" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="149" sofa="1" begin="138" end="143" Lemma="s1400" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="165" sofa="1" begin="145" end="150" Lemma="phase" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="173" sofa="1" begin="151" end="157" Lemma="ii/iii" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="237" sofa="1" begin="223" end="227" Lemma="cell" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="245" sofa="1" begin="228" end="232" Lemma="lung" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="253" sofa="1" begin="233" end="239" Lemma="cancer" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="269" sofa="1" begin="241" end="249" Lemma="lung-map" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="341" sofa="1" begin="285" end="291" Lemma="s1400g" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="357" sofa="1" begin="293" end="299" Lemma="s1400g" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="365" sofa="1" begin="300" end="309" Lemma="biomarker" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="373" sofa="1" begin="310" end="321" Lemma="eligibility" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="405" sofa="1" begin="344" end="357" Lemma="recombination" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="413" sofa="1" begin="358" end="364" Lemma="repair" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="421" sofa="1" begin="365" end="375" Lemma="deficiency" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="437" sofa="1" begin="377" end="381" Lemma="hrrd" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="501" sofa="1" begin="426" end="431" Lemma="group" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="517" sofa="1" begin="434" end="438" Lemma="hrrd" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="557" sofa="1" begin="460" end="473" Lemma="recombination" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="565" sofa="1" begin="474" end="480" Lemma="repair" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="573" sofa="1" begin="481" end="491" Lemma="deficiency" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="637" sofa="1" begin="531" end="541" Lemma="alteration" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="645" sofa="1" begin="542" end="546" Lemma="type" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="669" sofa="1" begin="560" end="568" Lemma="mutation" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="685" sofa="1" begin="570" end="580" Lemma="frameshift" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="717" sofa="1" begin="599" end="607" Lemma="missense" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="733" sofa="1" begin="612" end="620" Lemma="nonsense" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="781" sofa="1" begin="660" end="671" Lemma="consequence" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="853" sofa="1" begin="712" end="722" Lemma="alteration" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="869" sofa="1" begin="725" end="733" Lemma="mutation" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="933" sofa="1" begin="771" end="774" Lemma="hrr" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="941" sofa="1" begin="775" end="782" Lemma="pathway" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="997" sofa="1" begin="800" end="805" Lemma="bard1" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1013" sofa="1" begin="807" end="812" Lemma="brca1" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1029" sofa="1" begin="814" end="819" Lemma="brca2" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1045" sofa="1" begin="821" end="826" Lemma="brip1" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1061" sofa="1" begin="828" end="833" Lemma="chek1" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1077" sofa="1" begin="835" end="840" Lemma="chek2" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1093" sofa="1" begin="842" end="847" Lemma="fanca" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1109" sofa="1" begin="849" end="854" Lemma="fancc" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1125" sofa="1" begin="856" end="862" Lemma="fancd2" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1141" sofa="1" begin="864" end="869" Lemma="fancf" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1189" sofa="1" begin="883" end="887" Lemma="nbs1" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1213" sofa="1" begin="890" end="895" Lemma="palb2" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1229" sofa="1" begin="897" end="902" Lemma="rad51" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1245" sofa="1" begin="904" end="910" Lemma="rad51b" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1261" sofa="1" begin="912" end="919" Lemma="rad51l1" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1285" sofa="1" begin="922" end="928" Lemma="rad54l" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1301" sofa="1" begin="930" end="934" Lemma="rpa1" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1373" sofa="1" begin="973" end="981" Lemma="exposure" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1397" sofa="1" begin="989" end="994" Lemma="agent" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1421" sofa="1" begin="1002" end="1006" Lemma="parp" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1429" sofa="1" begin="1007" end="1016" Lemma="inhibitor" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1461" sofa="1" begin="1024" end="1033" Lemma="veliparib" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1477" sofa="1" begin="1035" end="1043" Lemma="olaparib" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1493" sofa="1" begin="1045" end="1054" Lemma="rucaparib" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1509" sofa="1" begin="1056" end="1065" Lemma="niraparib" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1525" sofa="1" begin="1067" end="1078" Lemma="talazoparib" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1541" sofa="1" begin="1080" end="1083" Lemma="bmn" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1597" sofa="1" begin="1105" end="1117" Lemma="pharmacology" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1661" sofa="1" begin="1158" end="1165" Lemma="disease" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1693" sofa="1" begin="1177" end="1185" Lemma="response" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1733" sofa="1" begin="1201" end="1209" Lemma="response" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1765" sofa="1" begin="1225" end="1232" Lemma="disease" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1773" sofa="1" begin="1233" end="1243" Lemma="assessment" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1813" sofa="1" begin="1287" end="1299" Lemma="chemotherapy" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1893" sofa="1" begin="1348" end="1355" Lemma="opinion" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1925" sofa="1" begin="1372" end="1381" Lemma="physician" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1965" sofa="1" begin="1398" end="1405" Lemma="disease" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="1973" sofa="1" begin="1406" end="1416" Lemma="assessment" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2061" sofa="1" begin="1465" end="1475" Lemma="impairment" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2085" sofa="1" begin="1496" end="1504" Lemma="function" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2109" sofa="1" begin="1525" end="1532" Lemma="disease" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2157" sofa="1" begin="1566" end="1576" Lemma="absorption" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2173" sofa="1" begin="1580" end="1591" Lemma="talazoparib" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2189" sofa="1" begin="1593" end="1596" Lemma="bmn" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2245" sofa="1" begin="1620" end="1627" Lemma="disease" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2269" sofa="1" begin="1642" end="1648" Lemma="nausea" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2301" sofa="1" begin="1660" end="1668" Lemma="diarrhea" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2317" sofa="1" begin="1670" end="1683" Lemma="malabsorption" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2325" sofa="1" begin="1684" end="1692" Lemma="syndrome" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2349" sofa="1" begin="1700" end="1705" Lemma="bowel" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2357" sofa="1" begin="1706" end="1715" Lemma="resection" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2397" sofa="1" begin="1734" end="1739" Lemma="ulcer" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2405" sofa="1" begin="1740" end="1747" Lemma="disease" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2493" sofa="1" begin="1795" end="1804" Lemma="intestine" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2501" sofa="1" begin="1805" end="1817" Lemma="inflammation" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2525" sofa="1" begin="1826" end="1831" Lemma="crohn" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2541" sofa="1" begin="1834" end="1841" Lemma="disease" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2565" sofa="1" begin="1856" end="1863" Lemma="colitis" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2621" sofa="1" begin="1895" end="1907" Lemma="registration" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2845" sofa="1" begin="2051" end="2054" Lemma="way" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2925" sofa="1" begin="2093" end="2097" Lemma="plan" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2949" sofa="1" begin="2106" end="2111" Lemma="while" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2965" sofa="1" begin="2115" end="2123" Lemma="protocol" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2973" sofa="1" begin="2124" end="2133" Lemma="treatment" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="2989" sofa="1" begin="2141" end="2155" Lemma="p-glycoprotein" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="3005" sofa="1" begin="2157" end="2161" Lemma="p-gp" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="3069" sofa="1" begin="2193" end="2199" Lemma="breast" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="3077" sofa="1" begin="2200" end="2206" Lemma="cancer" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="3085" sofa="1" begin="2207" end="2217" Lemma="resistance" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="3093" sofa="1" begin="2218" end="2225" Lemma="protein" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="3109" sofa="1" begin="2227" end="2231" Lemma="bcrp" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="3189" sofa="1" begin="2277" end="2282" Lemma="blood" PossibleAbbreviation="false"/><bmi:NNToken xmi:id="3229" sofa="1" begin="2323" end="2331" Lemma="analysis" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="21" sofa="1" begin="15" end="19" Lemma="true" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="229" sofa="1" begin="214" end="222" Lemma="squamous" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="285" sofa="1" begin="251" end="255" Lemma="true" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="397" sofa="1" begin="333" end="343" Lemma="homologous" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="453" sofa="1" begin="383" end="391" Lemma="positive" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="493" sofa="1" begin="407" end="425" Lemma="biomarker-positive" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="549" sofa="1" begin="449" end="459" Lemma="homologous" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="773" sofa="1" begin="649" end="659" Lemma="functional" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="845" sofa="1" begin="703" end="711" Lemma="eligible" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="925" sofa="1" begin="762" end="770" Lemma="critical" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="1309" sofa="1" begin="935" end="939" Lemma="true" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="1365" sofa="1" begin="967" end="972" Lemma="prior" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="1589" sofa="1" begin="1097" end="1104" Lemma="primary" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="1605" sofa="1" begin="1118" end="1122" Lemma="true" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="1653" sofa="1" begin="1151" end="1157" Lemma="stable" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="1685" sofa="1" begin="1169" end="1176" Lemma="partial" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="1725" sofa="1" begin="1192" end="1200" Lemma="complete" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="1757" sofa="1" begin="1219" end="1224" Lemma="first" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="1797" sofa="1" begin="1261" end="1271" Lemma="first-line" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="1805" sofa="1" begin="1272" end="1286" Lemma="platinum-based" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="1957" sofa="1" begin="1392" end="1397" Lemma="first" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="1997" sofa="1" begin="1425" end="1433" Lemma="eligible" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2005" sofa="1" begin="1434" end="1438" Lemma="true" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2077" sofa="1" begin="1479" end="1495" Lemma="gastrointestinal" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2101" sofa="1" begin="1508" end="1524" Lemma="gastrointestinal" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2237" sofa="1" begin="1609" end="1619" Lemma="ulcerative" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2261" sofa="1" begin="1629" end="1641" Lemma="uncontrolled" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2341" sofa="1" begin="1694" end="1699" Lemma="small" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2381" sofa="1" begin="1720" end="1726" Lemma="active" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2389" sofa="1" begin="1727" end="1733" Lemma="peptic" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2461" sofa="1" begin="1773" end="1779" Lemma="active" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2469" sofa="1" begin="1780" end="1785" Lemma="small" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2485" sofa="1" begin="1789" end="1794" Lemma="large" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2509" sofa="1" begin="1818" end="1822" Lemma="such" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2557" sofa="1" begin="1845" end="1855" Lemma="ulcerative" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2613" sofa="1" begin="1885" end="1894" Lemma="sub-study" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2637" sofa="1" begin="1909" end="1913" Lemma="true" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2677" sofa="1" begin="1931" end="1935" Lemma="able" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2701" sofa="1" begin="1944" end="1948" Lemma="oral" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2749" sofa="1" begin="1979" end="1983" Lemma="able" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2781" sofa="1" begin="2004" end="2009" Lemma="whole" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2853" sofa="1" begin="2055" end="2059" Lemma="true" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="2981" sofa="1" begin="2134" end="2140" Lemma="strong" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="3037" sofa="1" begin="2175" end="2179" Lemma="p-gp" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="3133" sofa="1" begin="2244" end="2248" Lemma="true" PossibleAbbreviation="false"/><bmi:JJToken xmi:id="3221" sofa="1" begin="2307" end="2322" Lemma="pharmacokinetic" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="29" sofa="1" begin="19" end="20" Lemma=":" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="157" sofa="1" begin="143" end="144" Lemma=":" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="261" sofa="1" begin="240" end="241" Lemma="-lrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="277" sofa="1" begin="249" end="250" Lemma="-rrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="293" sofa="1" begin="255" end="256" Lemma=":" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="349" sofa="1" begin="291" end="292" Lemma=";" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="429" sofa="1" begin="376" end="377" Lemma="-lrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="445" sofa="1" begin="381" end="382" Lemma="-rrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="613" sofa="1" begin="519" end="520" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="677" sofa="1" begin="568" end="569" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="701" sofa="1" begin="590" end="591" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="957" sofa="1" begin="788" end="789" Lemma=":" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="973" sofa="1" begin="793" end="794" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="989" sofa="1" begin="798" end="799" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1005" sofa="1" begin="805" end="806" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1021" sofa="1" begin="812" end="813" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1037" sofa="1" begin="819" end="820" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1053" sofa="1" begin="826" end="827" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1069" sofa="1" begin="833" end="834" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1085" sofa="1" begin="840" end="841" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1101" sofa="1" begin="847" end="848" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1117" sofa="1" begin="854" end="855" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1133" sofa="1" begin="862" end="863" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1149" sofa="1" begin="869" end="870" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1165" sofa="1" begin="876" end="877" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1181" sofa="1" begin="882" end="883" Lemma="-lrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1197" sofa="1" begin="887" end="888" Lemma="-rrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1205" sofa="1" begin="888" end="889" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1221" sofa="1" begin="895" end="896" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1237" sofa="1" begin="902" end="903" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1253" sofa="1" begin="911" end="912" Lemma="-lrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1269" sofa="1" begin="919" end="920" Lemma="-rrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1277" sofa="1" begin="920" end="921" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1293" sofa="1" begin="928" end="929" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1317" sofa="1" begin="939" end="940" Lemma=":" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1437" sofa="1" begin="1017" end="1018" Lemma="-lrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1453" sofa="1" begin="1022" end="1023" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1469" sofa="1" begin="1033" end="1034" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1485" sofa="1" begin="1043" end="1044" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1501" sofa="1" begin="1054" end="1055" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1517" sofa="1" begin="1065" end="1066" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1533" sofa="1" begin="1079" end="1080" Lemma="-lsb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1557" sofa="1" begin="1087" end="1088" Lemma="-rsb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1565" sofa="1" begin="1088" end="1089" Lemma="-rrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1613" sofa="1" begin="1122" end="1123" Lemma=":" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1669" sofa="1" begin="1165" end="1166" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1701" sofa="1" begin="1185" end="1186" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1821" sofa="1" begin="1299" end="1300" Lemma=";" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1869" sofa="1" begin="1340" end="1341" Lemma="-lrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="1933" sofa="1" begin="1381" end="1382" Lemma="-rrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2013" sofa="1" begin="1438" end="1439" Lemma=":" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2117" sofa="1" begin="1533" end="1537" Lemma="that" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2181" sofa="1" begin="1592" end="1593" Lemma="-lrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2205" sofa="1" begin="1600" end="1601" Lemma="-rrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2213" sofa="1" begin="1602" end="1603" Lemma="-lrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2229" sofa="1" begin="1607" end="1608" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2253" sofa="1" begin="1627" end="1628" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2277" sofa="1" begin="1648" end="1649" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2293" sofa="1" begin="1658" end="1659" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2309" sofa="1" begin="1668" end="1669" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2333" sofa="1" begin="1692" end="1693" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2365" sofa="1" begin="1715" end="1716" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2413" sofa="1" begin="1747" end="1748" Lemma="-rrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2421" sofa="1" begin="1748" end="1749" Lemma=";" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2573" sofa="1" begin="1864" end="1865" Lemma="-lrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2629" sofa="1" begin="1907" end="1908" Lemma="-rrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2645" sofa="1" begin="1913" end="1914" Lemma=":" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2717" sofa="1" begin="1960" end="1961" Lemma=";" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2861" sofa="1" begin="2059" end="2060" Lemma=":" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2909" sofa="1" begin="2087" end="2088" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="2997" sofa="1" begin="2156" end="2157" Lemma="-lrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="3013" sofa="1" begin="2161" end="2162" Lemma="-rrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="3029" sofa="1" begin="2173" end="2174" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="3053" sofa="1" begin="2188" end="2189" Lemma="," PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="3101" sofa="1" begin="2226" end="2227" Lemma="-lrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="3117" sofa="1" begin="2231" end="2232" Lemma="-rrb-" PossibleAbbreviation="false"/><bmi:PunctToken xmi:id="3141" sofa="1" begin="2248" end="2249" Lemma=":" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="37" sofa="1" begin="20" end="28" Lemma="patient" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="301" sofa="1" begin="256" end="264" Lemma="patient" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="621" sofa="1" begin="521" end="529" Lemma="criterion" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="693" sofa="1" begin="581" end="590" Lemma="deletion" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="709" sofa="1" begin="592" end="598" Lemma="indel" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="741" sofa="1" begin="621" end="630" Lemma="mutation" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="829" sofa="1" begin="696" end="701" Lemma="gene" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="949" sofa="1" begin="783" end="788" Lemma="gene" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="1325" sofa="1" begin="940" end="948" Lemma="patient" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="1621" sofa="1" begin="1123" end="1131" Lemma="patient" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="1829" sofa="1" begin="1301" end="1309" Lemma="patient" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="2021" sofa="1" begin="1439" end="1447" Lemma="patient" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="2429" sofa="1" begin="1750" end="1758" Lemma="patient" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="2597" sofa="1" begin="1875" end="1881" Lemma="month" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="2653" sofa="1" begin="1914" end="1922" Lemma="patient" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="2709" sofa="1" begin="1949" end="1960" Lemma="medication" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="2725" sofa="1" begin="1962" end="1970" Lemma="patient" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="2773" sofa="1" begin="1995" end="2003" Lemma="capsule" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="2869" sofa="1" begin="2060" end="2068" Lemma="patient" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="3021" sofa="1" begin="2163" end="2173" Lemma="inhibitor" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="3045" sofa="1" begin="2180" end="2188" Lemma="inducer" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="3125" sofa="1" begin="2233" end="2243" Lemma="inhibitor" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="3149" sofa="1" begin="2249" end="2257" Lemma="patient" PossibleAbbreviation="false"/><bmi:NNSToken xmi:id="3197" sofa="1" begin="2283" end="2292" Lemma="specimen" PossibleAbbreviation="false"/><bmi:MDToken xmi:id="45" sofa="1" begin="29" end="33" Lemma="must" PossibleAbbreviation="false"/><bmi:MDToken xmi:id="309" sofa="1" begin="265" end="269" Lemma="must" PossibleAbbreviation="false"/><bmi:MDToken xmi:id="1333" sofa="1" begin="949" end="953" Lemma="must" PossibleAbbreviation="false"/><bmi:MDToken xmi:id="1629" sofa="1" begin="1132" end="1136" Lemma="must" PossibleAbbreviation="false"/><bmi:MDToken xmi:id="2029" sofa="1" begin="1448" end="1451" Lemma="may" PossibleAbbreviation="false"/><bmi:MDToken xmi:id="2125" sofa="1" begin="1538" end="1541" Lemma="may" PossibleAbbreviation="false"/><bmi:MDToken xmi:id="2437" sofa="1" begin="1759" end="1763" Lemma="must" PossibleAbbreviation="false"/><bmi:MDToken xmi:id="2661" sofa="1" begin="1923" end="1927" Lemma="must" PossibleAbbreviation="false"/><bmi:MDToken xmi:id="2733" sofa="1" begin="1971" end="1975" Lemma="must" PossibleAbbreviation="false"/><bmi:MDToken xmi:id="2877" sofa="1" begin="2069" end="2073" Lemma="must" PossibleAbbreviation="false"/><bmi:MDToken xmi:id="3157" sofa="1" begin="2258" end="2262" Lemma="must" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="53" sofa="1" begin="34" end="38" Lemma="meet" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="317" sofa="1" begin="270" end="272" Lemma="be" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="765" sofa="1" begin="644" end="648" Lemma="have" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="1349" sofa="1" begin="958" end="962" Lemma="have" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="1637" sofa="1" begin="1137" end="1141" Lemma="have" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="1853" sofa="1" begin="1324" end="1328" Lemma="have" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="2045" sofa="1" begin="1456" end="1460" Lemma="have" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="2141" sofa="1" begin="1556" end="1561" Lemma="alter" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="2453" sofa="1" begin="1768" end="1772" Lemma="have" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="2669" sofa="1" begin="1928" end="1930" Lemma="be" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="2693" sofa="1" begin="1939" end="1943" Lemma="take" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="2741" sofa="1" begin="1976" end="1978" Lemma="be" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="2765" sofa="1" begin="1987" end="1994" Lemma="swallow" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="2893" sofa="1" begin="2078" end="2080" Lemma="be" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="2941" sofa="1" begin="2101" end="2105" Lemma="take" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="3165" sofa="1" begin="2263" end="2268" Lemma="agree" PossibleAbbreviation="false"/><bmi:VBToken xmi:id="3181" sofa="1" begin="2272" end="2276" Lemma="have" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="61" sofa="1" begin="39" end="42" Lemma="all" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="797" sofa="1" begin="675" end="678" Lemma="any" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="813" sofa="1" begin="682" end="685" Lemma="the" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="885" sofa="1" begin="737" end="740" Lemma="any" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="909" sofa="1" begin="748" end="751" Lemma="the" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="1389" sofa="1" begin="985" end="988" Lemma="any" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="1413" sofa="1" begin="1000" end="1001" Lemma="a" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="1677" sofa="1" begin="1167" end="1168" Lemma="a" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="1717" sofa="1" begin="1190" end="1191" Lemma="a" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="1885" sofa="1" begin="1344" end="1347" Lemma="the" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="1909" sofa="1" begin="1359" end="1362" Lemma="the" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="2053" sofa="1" begin="1461" end="1464" Lemma="any" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="2149" sofa="1" begin="1562" end="1565" Lemma="the" PossibleAbbreviation="false"/><bmi:DTToken xmi:id="2837" sofa="1" begin="2047" end="2050" Lemma="any" PossibleAbbreviation="false"/><bmi:CCToken xmi:id="77" sofa="1" begin="67" end="70" Lemma="and" PossibleAbbreviation="false"/><bmi:CCToken xmi:id="725" sofa="1" begin="608" end="611" Lemma="and" PossibleAbbreviation="false"/><bmi:CCToken xmi:id="1709" sofa="1" begin="1187" end="1189" Lemma="or" PossibleAbbreviation="false"/><bmi:CCToken xmi:id="2093" sofa="1" begin="1505" end="1507" Lemma="or" PossibleAbbreviation="false"/><bmi:CCToken xmi:id="2373" sofa="1" begin="1717" end="1719" Lemma="or" PossibleAbbreviation="false"/><bmi:CCToken xmi:id="2477" sofa="1" begin="1786" end="1788" Lemma="or" PossibleAbbreviation="false"/><bmi:CCToken xmi:id="2549" sofa="1" begin="1842" end="1844" Lemma="or" PossibleAbbreviation="false"/><bmi:CCToken xmi:id="2805" sofa="1" begin="2027" end="2029" Lemma="or" PossibleAbbreviation="false"/><bmi:CCToken xmi:id="2917" sofa="1" begin="2089" end="2092" Lemma="nor" PossibleAbbreviation="false"/><bmi:CCToken xmi:id="3061" sofa="1" begin="2190" end="2192" Lemma="or" PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="101" sofa="1" begin="94" end="100" Lemma="COMMON" PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="109" sofa="1" begin="101" end="112" Lemma="ELIGIBILITY" PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="117" sofa="1" begin="113" end="121" Lemma="CRITERIA" PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="181" sofa="1" begin="158" end="174" Lemma="Biomarker-Driven" PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="189" sofa="1" begin="175" end="181" Lemma="Master" PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="197" sofa="1" begin="182" end="190" Lemma="Protocol" PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="533" sofa="1" begin="442" end="445" Lemma="FMI" PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="589" sofa="1" begin="495" end="505" Lemma="Foundation" PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="597" sofa="1" begin="506" end="514" Lemma="Medicine" PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="605" sofa="1" begin="515" end="519" Lemma="Inc." PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="965" sofa="1" begin="790" end="793" Lemma="ATM" PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="981" sofa="1" begin="795" end="798" Lemma="ATR" PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="1157" sofa="1" begin="871" end="876" Lemma="FANCM" PossibleAbbreviation="false"/><bmi:NNPToken xmi:id="1173" sofa="1" begin="878" end="881" Lemma="NBN" PossibleAbbreviation="false"/><bmi:INToken xmi:id="125" sofa="1" begin="122" end="124" Lemma="as" PossibleAbbreviation="false"/><bmi:INToken xmi:id="141" sofa="1" begin="135" end="137" Lemma="in" PossibleAbbreviation="false"/><bmi:INToken xmi:id="205" sofa="1" begin="191" end="194" Lemma="for" PossibleAbbreviation="false"/><bmi:INToken xmi:id="389" sofa="1" begin="330" end="332" Lemma="as" PossibleAbbreviation="false"/><bmi:INToken xmi:id="469" sofa="1" begin="395" end="397" Lemma="as" PossibleAbbreviation="false"/><bmi:INToken xmi:id="525" sofa="1" begin="439" end="441" Lemma="by" PossibleAbbreviation="false"/><bmi:INToken xmi:id="581" sofa="1" begin="492" end="494" Lemma="by" PossibleAbbreviation="false"/><bmi:INToken xmi:id="789" sofa="1" begin="672" end="674" Lemma="in" PossibleAbbreviation="false"/><bmi:INToken xmi:id="805" sofa="1" begin="679" end="681" Lemma="of" PossibleAbbreviation="false"/><bmi:INToken xmi:id="877" sofa="1" begin="734" end="736" Lemma="in" PossibleAbbreviation="false"/><bmi:INToken xmi:id="901" sofa="1" begin="745" end="747" Lemma="of" PossibleAbbreviation="false"/><bmi:INToken xmi:id="1405" sofa="1" begin="995" end="999" Lemma="with" PossibleAbbreviation="false"/><bmi:INToken xmi:id="1573" sofa="1" begin="1090" end="1092" Lemma="as" PossibleAbbreviation="false"/><bmi:INToken xmi:id="1741" sofa="1" begin="1210" end="1212" Lemma="at" PossibleAbbreviation="false"/><bmi:INToken xmi:id="1781" sofa="1" begin="1244" end="1249" Lemma="after" PossibleAbbreviation="false"/><bmi:INToken xmi:id="1877" sofa="1" begin="1341" end="1343" Lemma="in" PossibleAbbreviation="false"/><bmi:INToken xmi:id="1901" sofa="1" begin="1356" end="1358" Lemma="of" PossibleAbbreviation="false"/><bmi:INToken xmi:id="1941" sofa="1" begin="1383" end="1385" Lemma="at" PossibleAbbreviation="false"/><bmi:INToken xmi:id="2069" sofa="1" begin="1476" end="1478" Lemma="of" PossibleAbbreviation="false"/><bmi:INToken xmi:id="2165" sofa="1" begin="1577" end="1579" Lemma="of" PossibleAbbreviation="false"/><bmi:INToken xmi:id="2517" sofa="1" begin="1823" end="1825" Lemma="as" PossibleAbbreviation="false"/><bmi:INToken xmi:id="2581" sofa="1" begin="1865" end="1871" Lemma="within" PossibleAbbreviation="false"/><bmi:INToken xmi:id="2605" sofa="1" begin="1882" end="1884" Lemma="of" PossibleAbbreviation="false"/><bmi:INToken xmi:id="2789" sofa="1" begin="2010" end="2017" Lemma="without" PossibleAbbreviation="false"/><bmi:INToken xmi:id="2829" sofa="1" begin="2044" end="2046" Lemma="in" PossibleAbbreviation="false"/><bmi:INToken xmi:id="2957" sofa="1" begin="2112" end="2114" Lemma="on" PossibleAbbreviation="false"/><bmi:INToken xmi:id="3213" sofa="1" begin="2303" end="2306" Lemma="for" PossibleAbbreviation="false"/><bmi:VBNToken xmi:id="133" sofa="1" begin="125" end="134" Lemma="specify" PossibleAbbreviation="false"/><bmi:VBNToken xmi:id="221" sofa="1" begin="206" end="213" Lemma="treat" PossibleAbbreviation="false"/><bmi:VBNToken xmi:id="325" sofa="1" begin="273" end="281" Lemma="assign" PossibleAbbreviation="false"/><bmi:VBNToken xmi:id="381" sofa="1" begin="322" end="329" Lemma="define" PossibleAbbreviation="false"/><bmi:VBNToken xmi:id="821" sofa="1" begin="686" end="695" Lemma="specify" PossibleAbbreviation="false"/><bmi:VBNToken xmi:id="1357" sofa="1" begin="963" end="966" Lemma="have" PossibleAbbreviation="false"/><bmi:VBNToken xmi:id="1645" sofa="1" begin="1142" end="1150" Lemma="achieve" PossibleAbbreviation="false"/><bmi:VBNToken xmi:id="1861" sofa="1" begin="1329" end="1339" Lemma="progress" PossibleAbbreviation="false"/><bmi:VBNToken xmi:id="3205" sofa="1" begin="2293" end="2302" Lemma="submit" PossibleAbbreviation="false"/><bmi:RBToken xmi:id="213" sofa="1" begin="195" end="205" Lemma="previously" PossibleAbbreviation="false"/><bmi:RBToken xmi:id="1341" sofa="1" begin="954" end="957" Lemma="not" PossibleAbbreviation="false"/><bmi:RBToken xmi:id="1989" sofa="1" begin="1421" end="1424" Lemma="not" PossibleAbbreviation="false"/><bmi:RBToken xmi:id="2037" sofa="1" begin="1452" end="1455" Lemma="not" PossibleAbbreviation="false"/><bmi:RBToken xmi:id="2133" sofa="1" begin="1542" end="1555" Lemma="significantly" PossibleAbbreviation="false"/><bmi:RBToken xmi:id="2445" sofa="1" begin="1764" end="1767" Lemma="not" PossibleAbbreviation="false"/><bmi:RBToken xmi:id="2885" sofa="1" begin="2074" end="2077" Lemma="not" PossibleAbbreviation="false"/><bmi:TOToken xmi:id="333" sofa="1" begin="282" end="284" Lemma="to" PossibleAbbreviation="false"/><bmi:TOToken xmi:id="757" sofa="1" begin="641" end="643" Lemma="to" PossibleAbbreviation="false"/><bmi:TOToken xmi:id="1381" sofa="1" begin="982" end="984" Lemma="to" PossibleAbbreviation="false"/><bmi:TOToken xmi:id="1845" sofa="1" begin="1321" end="1323" Lemma="to" PossibleAbbreviation="false"/><bmi:TOToken xmi:id="2685" sofa="1" begin="1936" end="1938" Lemma="to" PossibleAbbreviation="false"/><bmi:TOToken xmi:id="2757" sofa="1" begin="1984" end="1986" Lemma="to" PossibleAbbreviation="false"/><bmi:TOToken xmi:id="2933" sofa="1" begin="2098" end="2100" Lemma="to" PossibleAbbreviation="false"/><bmi:TOToken xmi:id="3173" sofa="1" begin="2269" end="2271" Lemma="to" PossibleAbbreviation="false"/><bmi:VBZToken xmi:id="461" sofa="1" begin="392" end="394" Lemma="be" PossibleAbbreviation="false"/><bmi:VBZToken xmi:id="477" sofa="1" begin="398" end="405" Lemma="follow" PossibleAbbreviation="false"/><bmi:SYMToken xmi:id="485" sofa="1" begin="405" end="406" Lemma="*" PossibleAbbreviation="false"/><bmi:SYMToken xmi:id="509" sofa="1" begin="431" end="433" Lemma="**" PossibleAbbreviation="false"/><bmi:SYMToken xmi:id="629" sofa="1" begin="529" end="530" Lemma="*" PossibleAbbreviation="false"/><bmi:SYMToken xmi:id="653" sofa="1" begin="546" end="548" Lemma="**" PossibleAbbreviation="false"/><bmi:SYMToken xmi:id="837" sofa="1" begin="701" end="702" Lemma="*" PossibleAbbreviation="false"/><bmi:SYMToken xmi:id="861" sofa="1" begin="722" end="724" Lemma="**" PossibleAbbreviation="false"/><bmi:CDToken xmi:id="541" sofa="1" begin="445" end="448" Lemma="***" PossibleAbbreviation="false"/><bmi:CDToken xmi:id="893" sofa="1" begin="741" end="744" Lemma="one" PossibleAbbreviation="false"/><bmi:CDToken xmi:id="1549" sofa="1" begin="1084" end="1087" Lemma="673" PossibleAbbreviation="false"/><bmi:CDToken xmi:id="2197" sofa="1" begin="1597" end="1600" Lemma="673" PossibleAbbreviation="false"/><bmi:CDToken xmi:id="2589" sofa="1" begin="1872" end="1874" Lemma="12" PossibleAbbreviation="false"/><bmi:VBGToken xmi:id="661" sofa="1" begin="549" end="559" 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Governor="869" Dependent="853" Relation="compound"/><bmi:Dependency xmi:id="5787" sofa="1" begin="722" end="733" Governor="869" Dependent="861" Relation="compound"/><bmi:Dependency xmi:id="5741" sofa="1" begin="725" end="793" Governor="869" Dependent="965" Relation="dep"/><bmi:Dependency xmi:id="5718" sofa="1" begin="725" end="789" Governor="869" Dependent="957" Relation="punct"/><bmi:Dependency xmi:id="5810" sofa="1" begin="725" end="744" Governor="869" Dependent="893" Relation="nmod"/><bmi:Dependency xmi:id="5856" sofa="1" begin="734" end="744" Governor="893" Dependent="877" Relation="case"/><bmi:Dependency xmi:id="5879" sofa="1" begin="737" end="744" Governor="893" Dependent="885" Relation="det"/><bmi:Dependency xmi:id="5833" sofa="1" begin="741" end="788" Governor="893" Dependent="949" Relation="nmod"/><bmi:Dependency xmi:id="5902" sofa="1" begin="745" end="788" Governor="949" Dependent="901" Relation="case"/><bmi:Dependency xmi:id="5925" sofa="1" begin="748" end="788" Governor="949" Dependent="909" Relation="dep"/><bmi:Dependency xmi:id="5948" sofa="1" begin="752" end="788" Governor="949" Dependent="917" Relation="case"/><bmi:Dependency xmi:id="5971" sofa="1" begin="762" end="788" Governor="949" Dependent="925" Relation="amod"/><bmi:Dependency xmi:id="5994" sofa="1" begin="771" end="788" Governor="949" Dependent="933" Relation="compound"/><bmi:Dependency xmi:id="6017" sofa="1" begin="775" end="788" Governor="949" Dependent="941" Relation="compound"/><bmi:Dependency xmi:id="6730" sofa="1" begin="790" end="966" Governor="965" Dependent="1357" Relation="dep"/><bmi:Dependency xmi:id="6707" sofa="1" begin="790" end="940" Governor="965" Dependent="1317" Relation="punct"/><bmi:Dependency xmi:id="6684" sofa="1" begin="790" end="939" Governor="965" Dependent="1309" Relation="amod"/><bmi:Dependency xmi:id="6661" sofa="1" begin="790" end="929" Governor="965" Dependent="1293" Relation="punct"/><bmi:Dependency xmi:id="6638" sofa="1" begin="790" end="928" 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sofaString="NCI-2017-00135&#9;True:Patients must meet all SCREENING/PRE-SCREENING and SUB-STUDY REGISTRATION COMMON ELIGIBILITY CRITERIA as specified in S1400: Phase II/III Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (Lung-Map)&#9;True:Patients must be assigned to S1400G; S1400G biomarker eligibility defined as homologous recombination repair deficiency (HRRD) positive is as follows* Biomarker-positive group** HRRD by FMI*** Homologous recombination repair deficiency by Foundation Medicine Inc., criteria* Alteration type** Truncating mutation, frameshift deletions, indels missense and nonsense mutations predicted to have functional consequence in any of the specified genes* Eligible alteration** Mutation in any one of the following critical HRR pathway genes: ATM, ATR, BARD1, BRCA1, BRCA2, BRIP1, CHEK1, CHEK2, FANCA, FANCC, FANCD2, FANCF, FANCM, NBN (NBS1), PALB2, RAD51, RAD51B (RAD51L1), RAD54L, RPA1&#9;True:Patients must not have had prior exposure to any agent with a PARP inhibitor (e.g., veliparib, olaparib, rucaparib, niraparib, talazoparib [BMN 673]) as its primary pharmacology&#9;True:Patients must have achieved stable disease, a partial response, or a complete response at their first disease assessment after initiating first-line platinum-based chemotherapy; patients determined to have progressed (in the opinion of the treating physician) at their first disease assessment are not eligible&#9;True:Patients may not have any impairment of gastrointestinal function or gastrointestinal disease that may significantly alter the absorption of talazoparib (BMN 673) (e.g., ulcerative disease, uncontrolled nausea, vomiting, diarrhea, malabsorption syndrome, small bowel resection, or active peptic ulcer disease); patients must not have active small or large intestine inflammation such as Crohn's disease or ulcerative colitis (within 12 months of sub-study registration)&#9;True:Patients must be able to take oral medications; patients must be able to swallow capsules whole without crushing or altering them in any way&#9;True:Patients must not be taking, nor plan to take while on protocol treatment strong P-glycoprotein (P-gp) inhibitors, P-gp inducers, or breast cancer resistance protein (BCRP) inhibitors&#9;True:Patients must agree to have blood specimens submitted for pharmacokinetic analysis&#10;"/><cas:View sofa="1" members="8 13 69 85 93 149 165 173 237 245 253 269 341 357 365 373 405 413 421 437 501 517 557 565 573 637 645 669 685 717 733 781 853 869 933 941 997 1013 1029 1045 1061 1077 1093 1109 1125 1141 1189 1213 1229 1245 1261 1285 1301 1373 1397 1421 1429 1461 1477 1493 1509 1525 1541 1597 1661 1693 1733 1765 1773 1813 1893 1925 1965 1973 2061 2085 2109 2157 2173 2189 2245 2269 2301 2317 2325 2349 2357 2397 2405 2493 2501 2525 2541 2565 2621 2845 2925 2949 2965 2973 2989 3005 3069 3077 3085 3093 3109 3189 3229 21 229 285 397 453 493 549 773 845 925 1309 1365 1589 1605 1653 1685 1725 1757 1797 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