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Terminology="SNOMED" TerminologyIdentifier="89780004####228166004" Certainty="affirmed"/><bmi:BioMedicalEntity xmi:id="2004" sofa="1" begin="396" end="418" Terminology="SNOMED" TerminologyIdentifier="183964008####152190007" Certainty="affirmed"/><cas:Sofa xmi:id="1" sofaNum="1" sofaID="_InitialView" mimeType="text" sofaString="Human immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligible because of the potential for pharmacokinetic interactions with MLN0128 and AZD9291;  in addition, these patients are at increased risk of lethal infections when treated with marrow-suppressive therapy; appropriate studies will be undertaken in patients receiving combination antiretroviral therapy when indicated"/><cas:View sofa="1" members="8 13 69 101 125 173 309 349 373 445 21 29 45 93 109 157 197 213 237 293 357 437 453 37 53 61 221 245 365 77 181 261 317 381 421 85 133 141 165 189 229 277 301 341 413 117 269 149 253 205 285 333 405 469 325 461 389 397 429 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