1 |
10.2 |
Known human immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligible |
0.1 |
5.0 |
10.3,10.4 |
70,15 |
2 |
10.3 |
HIV positive with antiretroviral therapy excluded |
0.2 |
6.0 |
10.2,10.4 |
70,20 |
3 |
10.4 |
HIV positive excluded |
0.3 |
7.0 |
10.2,10.3 |
15,20 |
4 |
11.1 |
Hemoglobin >= 9.0 mg/dl |
0.3 |
7.0 |
11.2 |
90 |
5 |
11.2 |
Hemoglobin >= 8.0 mg/dl |
0.3 |
7.0 |
11.1 |
90 |
6 |
12.1 |
Suspected diagnosis of resectable non-small cell lung cancer |
0.2 |
8.0 |
12.2 |
90 |
7 |
12.2 |
nonsquamous histology |
0.3 |
8.0 |
12.1 |
90 |
8 |
12.3 |
squamous cell carcinoma are eligible only if the registering site has EA5142 Institutional Review Board (IRB) approved |
0.1 |
3.0 |
nan |
nan |
9 |
13.1 |
Suspected clinical stage of IIIA, II (IIA or IIB) or large IB are eligible |
0.2 |
4.0 |
13.2,13.3,13.4,13.5 |
90,90,90,90 |
10 |
13.2 |
Stage IIIA |
0.3 |
7.0 |
13.1 |
90 |
11 |
13.3 |
Stage II |
0.3 |
7.0 |
13.1 |
90 |
12 |
13.4 |
large IB |
0.3 |
7.0 |
13.1 |
90 |
13 |
13.5 |
size >= 4cm |
0.3 |
7.0 |
13.1 |
90 |
14 |
13.6 |
IB tumors < 4cm are NOT eligible |
0.3 |
7.0 |
13.7 |
90 |
15 |
13.7 |
IB tumors < 3cm are NOT eligible |
0.3 |
5.0 |
13.6 |
70 |
16 |
14.1 |
Completely resected non-small cell lung cancer with negative margins |
0.1 |
nan |
nan |
nan |
17 |
15.1 |
Eastern Cooperative Oncology Group performance status 0-1 |
0.3 |
8.0 |
15.2 |
90 |
18 |
15.2 |
ECOG performance status 0-1 |
0.4 |
8.0 |
15.1 |
90 |
19 |
16.1 |
No patients who have received neoadjuvant therapy |
0.2 |
7.0 |
16.2,16.3 |
90,90 |
20 |
16.2 |
No Radio Therapy |
0.4 |
7.0 |
16.1 |
90 |
21 |
16.3 |
No Chemo Therapy |
0.4 |
7.0 |
16.1 |
90 |
22 |
17.1 |
No locally advanced or metastatic cancer requiring systemic therapy within 5 years |
0.3 |
7.0 |
17.2 |
90 |
23 |
17.2 |
Metastatic cancer requiring systemic therapy within 5 years excluded |
0.4 |
7.0 |
17.1 |
90 |
24 |
18.1 |
no secondary primary lung cancer diagnosed concurrently or within 2 year |
0.2 |
7.0 |
18.2,18.3 |
90 |
25 |
18.2 |
no secondary primary lung cancer diagnosed within 2 year |
0.4 |
7.0 |
18.1 |
90 |
26 |
18.2 |
no secondary primary lung cancer diagnosed concurrently |
0.4 |
7.0 |
18.1 |
90 |
27 |
19.1 |
No prior treatment with agents targeting EGFR mutation, ALK rearrangement, and PD-1/PD-L1/CTLA-4 |
0.2 |
7.0 |
19.2 |
80 |
28 |
19.2 |
No prior treatment with agents targeting EGFR mutation |
0.4 |
7.0 |
19.1 |
60 |
29 |
20.1 |
No patients known to be pregnant or lactating |
0.3 |
8.0 |
20.2 |
90 |
30 |
20.2 |
No patients known to be pregnant |
0.4 |
8.0 |
20.1 |
90 |