--- a +++ b/readme.md @@ -0,0 +1,72 @@ + + +Modeling Clinical Trial Attrition Using Machine Intelligence: +A driver analytics case study using 1,325 trials representing one million patients +--------------------------------------------------------------------------------------------------------------- +This file is the readme.txt file for the code folder that contains the R code that was used in the model + + +TABLE OF CONTENTS +----------------- + +* Full Author List + +* Introduction + +* Requirements + +* Folder Contents + +* Contact + +Full Author List +---------------- +Emmette Hutchison, Youyi Zhang, Sreenath Nampally, Imran Khan Neelufer, Vlad Malkov, Jim Weatherall, Faisal Khan and Khader Shameer + + +Introduction +------------ +Patient attrition, also referred to as dropout or patient withdrawal, occurs when patients enrolled +in a clinical trial either withdraw or are lost to follow-up by the clinical site and trial sponsor. + + +Requirements +------------ +This was performed using RStudio and R. The versions of RStudio and R are listed below: +RStudio 1.0.44, which can be downloaded from https://rstudio.com/products/rstudio/download/ +R 3.5.2 (2018-12-20). RStudio can be installed from https://cran.r-project.org/mirrors.html + +The project requires the following R packages. The version numbers indicate the version of the packages +that were used in the analysis. Please install the following packages using the command below in your R +Environment + + SuperLearner==2.0-26 + MASS==7.3-51.5 + ranger==0.12.1 + ipred==0.9-9 + kernlab==0.9-29 + arm==1.10-1 + dplyr==1.4.2 + caret==6.0-84 + parallel==3.5.2 + +Folder Contents +---------------- +This folder contains the data files that was used in the analysis. The file descriptions are listed below: + +``` +|---- readme.md : readme file for the data folder +| +|---- code : This folder contains the code required for the pre-processing of raw data and running the predictive model results, +| further explanation is available in a readme file within this folder +| +|---- data: This folder contains two sub-folders, another readme file in the folder will explain the overview on each folder content. + |---- analysis_ready +|---- requirments.txt : is a file which lists the libraries used in the model building exercise, this file can be used to install the packages needed. +| +| Using command "Install.Packages("package name") one can easily install the required packages +``` + +Contact +-------- +shameer.khader@astrazeneca.com