[9b26b7]: / deepvariant / make_examples_somatic_test.py

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# Copyright 2023 Google LLC.
#
# Redistribution and use in source and binary forms, with or without
# modification, are permitted provided that the following conditions
# are met:
#
# 1. Redistributions of source code must retain the above copyright notice,
# this list of conditions and the following disclaimer.
#
# 2. Redistributions in binary form must reproduce the above copyright
# notice, this list of conditions and the following disclaimer in the
# documentation and/or other materials provided with the distribution.
#
# 3. Neither the name of the copyright holder nor the names of its
# contributors may be used to endorse or promote products derived from this
# software without specific prior written permission.
#
# THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
# AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
# IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
# ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
# LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
# CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
# SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
# INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
# CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
# ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
# POSSIBILITY OF SUCH DAMAGE.
"""Tests for make_examples_somatic."""
import os
from absl import flags
from absl import logging
from absl.testing import absltest
from absl.testing import flagsaver
from absl.testing import parameterized
from deepvariant import make_examples_core
from deepvariant import make_examples_somatic
from deepvariant import testdata
from third_party.nucleus.testing import test_utils
FLAGS = flags.FLAGS
def setUpModule():
logging.set_verbosity(logging.FATAL)
testdata.init()
class MakeExamplesSomaticEnd2EndTest(parameterized.TestCase):
@flagsaver.flagsaver
def test_options_and_sample_names(self):
FLAGS.ref = testdata.CHR20_FASTA
FLAGS.reads_normal = testdata.CHR20_BAM
FLAGS.reads_tumor = testdata.CHR20_BAM
FLAGS.sample_name_normal = 'NORMAL'
FLAGS.sample_name_tumor = 'TUMOR'
FLAGS.mode = 'calling'
FLAGS.examples = ''
options = make_examples_somatic.default_options(add_flags=True)
self.assertLen(options.sample_options, 2)
normal_sample_options = options.sample_options[
make_examples_somatic.NORMAL_SAMPLE_INDEX
]
tumor_sample_options = options.sample_options[
make_examples_somatic.MAIN_SAMPLE_INDEX
]
self.assertEqual(normal_sample_options.name, 'NORMAL')
self.assertEqual(tumor_sample_options.name, 'TUMOR')
@flagsaver.flagsaver
def test_make_examples_somatic_end2end_check_calling_examples_suffixes(self):
FLAGS.ref = testdata.CHR20_FASTA
FLAGS.reads_normal = testdata.CHR20_BAM
FLAGS.reads_tumor = testdata.CHR20_BAM
FLAGS.sample_name_normal = 'NORMAL'
FLAGS.sample_name_tumor = 'TUMOR'
FLAGS.mode = 'calling'
FLAGS.examples = test_utils.test_tmpfile('TEST_SUFFIX.tfrecord.gz')
with_normal_suffix = test_utils.test_tmpfile(
'TEST_SUFFIX_normal.tfrecord.gz'
)
with_tumor_suffix = test_utils.test_tmpfile('TEST_SUFFIX_tumor.tfrecord.gz')
options = make_examples_somatic.default_options(add_flags=True)
FLAGS.regions = 'chr20:10,000,000-10,010,000'
options = make_examples_somatic.default_options(add_flags=True)
make_examples_core.make_examples_runner(options)
# This shows that tumor examples in calling mode are generated without the
# _tumor suffixes, because it's the only samples generating output.
self.assertFalse(os.path.exists(with_normal_suffix))
self.assertFalse(os.path.exists(with_tumor_suffix))
self.assertTrue(os.path.exists(FLAGS.examples))
if __name__ == '__main__':
absltest.main()