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"""Classes for reading and writing BedGraph files.
The BedGraph format is described at
https://genome.ucsc.edu/goldenpath/help/bedgraph.html
API for reading:
```python
from third_party.nucleus.io import bedgraph
# Iterate through all records.
with bed.BedGraphReader(input_path) as reader:
for record in reader:
print(record)
```
where `record` is a `nucleus.genomics.v1.BedGraphRecord` protocol buffer.
API for writing:
```python
from third_party.nucleus.io import bedgraph
from third_party.nucleus.protos import bedgraph_pb2
# records is an iterable of nucleus.genomics.v1.BedGraphRecord protocol buffers.
records = ...
# Write all records to the desired output path.
with bed.BedGraphWriter(output_path) as writer:
for record in records:
writer.write(record)
```
For both reading and writing, if the path provided to the constructor contains
'.tfrecord' as an extension, a `TFRecord` file is assumed and attempted to be
read or written. Otherwise, the filename is treated as a true BedGraph file.
Files that end in a '.gz' suffix cause the file to be treated as compressed
(with BGZF if it is a BedGraph file, and with gzip if it is a TFRecord file).
"""
from __future__ import absolute_import
from __future__ import division
from __future__ import print_function
from third_party.nucleus.io import genomics_reader
from third_party.nucleus.io import genomics_writer
from third_party.nucleus.io.python import bedgraph_reader
from third_party.nucleus.io.python import bedgraph_writer
from third_party.nucleus.protos import bedgraph_pb2
class NativeBedGraphReader(genomics_reader.GenomicsReader):
"""Class for reading from native BedGraph files.
Most users will want to use BedGraphReader instead, because it dynamically
dispatches between reading native BedGraph files and TFRecord files based on
the filename's extension.
"""
def __init__(self, input_path, num_fields=0):
"""Initializes a NativeBedGraphReader.
Args:
input_path: string. A path to a resource containing BedGraph records.
num_fields: int. The number of fields to read in the BedGraph. If unset or
set to zero, all fields in the input are read.
"""
super(NativeBedGraphReader, self).__init__()
bedgraph_path = input_path.encode('utf8')
self._reader = bedgraph_reader.BedGraphReader.from_file(bedgraph_path)
def query(self):
"""Returns an iterator for going through the records in the region.
NOTE: This function is not currently implemented by NativeBedGraphReader
though it could be implemented for sorted, tabix-indexed BedGraph files.
"""
raise NotImplementedError('Can not currently query a BedGraph file')
def iterate(self):
"""Returns an iterable of BedGraphRecord protos in the file."""
return self._reader.iterate()
def __exit__(self, exit_type, exit_value, exit_traceback):
self._reader.__exit__(exit_type, exit_value, exit_traceback)
class BedGraphReader(genomics_reader.DispatchingGenomicsReader):
"""Class for reading BedGraphRecord protos from BedGraph or TFRecord files."""
def _native_reader(self, input_path, **kwargs):
return NativeBedGraphReader(input_path, **kwargs)
def _record_proto(self):
return bedgraph_pb2.BedGraphRecord
class NativeBedGraphWriter(genomics_writer.GenomicsWriter):
"""Class for writing to native BedGraph files.
Most users will want BedGraphWriter, which will write to either native
BedGraph files or TFRecord files, based on the output filename's extension.
"""
def __init__(self, output_path, header=None):
"""Initializer for NativeBedGraphWriter.
Args:
output_path: str. The path to which to write the BedGraph file.
"""
super(NativeBedGraphWriter, self).__init__()
self._writer = bedgraph_writer.BedGraphWriter.to_file(output_path)
def write(self, proto):
self._writer.write(proto)
def __exit__(self, exit_type, exit_value, exit_traceback):
self._writer.__exit__(exit_type, exit_value, exit_traceback)
class BedGraphWriter(genomics_writer.DispatchingGenomicsWriter):
"""Class for writing BedGraphRecord protos to BedGraph or TFRecord files."""
def _native_writer(self, output_path):
return NativeBedGraphWriter(output_path)