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/*
* Copyright 2017 Google LLC.
*
* Redistribution and use in source and binary forms, with or without
* modification, are permitted provided that the following conditions
* are met:
*
* 1. Redistributions of source code must retain the above copyright notice,
* this list of conditions and the following disclaimer.
*
* 2. Redistributions in binary form must reproduce the above copyright
* notice, this list of conditions and the following disclaimer in the
* documentation and/or other materials provided with the distribution.
*
* 3. Neither the name of the copyright holder nor the names of its
* contributors may be used to endorse or promote products derived from this
* software without specific prior written permission.
*
* THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
* AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
* IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
* ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
* LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
* CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
* SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
* INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
* CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
* ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
* POSSIBILITY OF SUCH DAMAGE.
*/
#ifndef LEARNING_GENOMICS_DEEPVARIANT_REALIGNER_SSW_H_
#define LEARNING_GENOMICS_DEEPVARIANT_REALIGNER_SSW_H_
#include "src/ssw_cpp.h"
namespace learning {
namespace genomics {
namespace deepvariant {
using std::string;
// This wrapper library exists solely to provide "string" interface methods,
// since CLIF cannot wrap char*. Note that we include this wrapper class here
// rather than in SSW, so as to keep things clean for OSS.
class Alignment : public StripedSmithWaterman::Alignment {};
class Filter : public StripedSmithWaterman::Filter {
public:
Filter();
Filter(const bool& pos, const bool& cigar,
const uint16_t& score, const uint16_t& dis);
};
class Aligner : public StripedSmithWaterman::Aligner {
public:
Aligner();
Aligner(const uint8_t& match_score,
const uint8_t& mismatch_penalty,
const uint8_t& gap_opening_penalty,
const uint8_t& gap_extending_penalty);
int SetReferenceSequence(const string& reference);
int Align(const string& query, const Filter& filter, Alignment* alignment)
const;
};
} // namespace deepvariant
} // namespace genomics
} // namespace learning
#endif // LEARNING_GENOMICS_DEEPVARIANT_REALIGNER_SSW_H_