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# Gene Tier aSHM QC Mean Variant Quality citekey PMID MutationEffect Mutation-PMID Effect-CiteKey Additional_Support
1 ARID1A 1 loveGeneticLandscapeMutations2012 23143597 LOF 38458187 barisicARID1AOrchestratesSWI2024 giulino-rothTargetedGenomicSequencing2012
2 BACH2 1 TRUE grandeGenomewideDiscoverySomatic2019 30617194 LOF 26522720 hunterNFkBSubunitCRel2016 paneaWholeGenomeLandscape2019
3 BCL6 1 TRUE PASS 4 loveGeneticLandscapeMutations2012 30617194 LOF 12504096 masclePointMutationsBCL62003 grandeGenomewideDiscoverySomatic2019
4 BCL7A 1 TRUE grandeGenomewideDiscoverySomatic2019 30617194 LOF 32576963 balinas-gaviraFrequentMutationsAminoterminal2020 thomasGeneticSubgroupsInform2023
5 BMP7 1 paneaWholeGenomeLandscape2019 31558468 thomasGeneticSubgroupsInform2023
6 CCND3 1 richterRecurrentMutationID32012 23143595 GOF 22885699 schmitzBurkittLymphomaPathogenesis2012 abateDistinctViralMutational2015
7 CHD8 1 grandeGenomewideDiscoverySomatic2019 36201743 paneaWholeGenomeLandscape2019
8 CREBBP 1 PASS 4 loveGeneticLandscapeMutations2012 23143597 LOF 33431788 huangCREBBPEP300Mutations2021 grandeGenomewideDiscoverySomatic2019
9 DDX3X 1 schmitzBurkittLymphomaPathogenesis2012 22885699 LOF 34437837 gongSequentialInverseDysregulation2021 abateDistinctViralMutational2015
10 EZH2 1 PASS 5 loveGeneticLandscapeMutations2012 23143597
11 FBXO11 1 richterRecurrentMutationID32012 23143595 LOF 22113614 duanFBXO11TargetsBCL62011 grandeGenomewideDiscoverySomatic2019
12 FOXO1 1 schmitzBurkittLymphomaPathogenesis2012 22885699 GOF 23460611 trinhAnalysisFOXO1Mutations grandeGenomewideDiscoverySomatic2019
13 GNA13 1 schmitzBurkittLymphomaPathogenesis2012 22885699 LOF 26616858 ohayreInactivatingMutationsGNA132016 loveGeneticLandscapeMutations2012
14 GNAI2 1 grandeGenomewideDiscoverySomatic2019 30617194 thomasGeneticSubgroupsInform2023
15 HIST1H1E 1 TRUE grandeGenomewideDiscoverySomatic2019 31558468 paneaWholeGenomeLandscape2019
16 HNRNPU 1 TRUE paneaWholeGenomeLandscape2019 31558468 thomasGeneticSubgroupsInform2023
17 ID3 1 richterRecurrentMutationID32012 23143595 loveGeneticLandscapeMutations2012
18 KMT2D 1 grandeGenomewideDiscoverySomatic2019 30617194 LOF 26366712 zhangDisruptionKMT2DPerturbs2015 paneaWholeGenomeLandscape2019
19 MYC 1 TRUE johnstonCmycHypermutationBurkitt1992 1297477 GOF 38565249 freieGermlinePointMutation2024 loveGeneticLandscapeMutations2012
20 P2RY8 1 muppidiLossSignalingGa132014 25274307 LOF 25274307 muppidiLossSignalingGa132014 grandeGenomewideDiscoverySomatic2019
21 PCBP1 1 schmitzBurkittLymphomaPathogenesis2012 22885699 wagenerPCBP1GeneEncoding2015
22 PHF6 1 thomasGeneticSubgroupsInform2023 36201743 zhouSporadicEndemicBurkitt2019
23 PTEN 1 loveGeneticLandscapeMutations2012 23143597 LOF 23840064 pfeiferPTENLossDefines2013 paneaWholeGenomeLandscape2019
24 RFX7 1 grandeGenomewideDiscoverySomatic2019 30617194 LOF 30926791 weberPiggyBacTransposonTools2019 paneaWholeGenomeLandscape2019
25 RHOA 1 richterRecurrentMutationID32012 23143595 LOF 26616858 ohayreInactivatingMutationsGNA132016 grandeGenomewideDiscoverySomatic2019
26 SIN3A 1 grandeGenomewideDiscoverySomatic2019 30617194 paneaWholeGenomeLandscape2019
27 SMARCA4 1 richterRecurrentMutationID32012 23143595 LOF 33144586 fernandoFunctionalCharacterizationSMARCA42020 grandeGenomewideDiscoverySomatic2019
28 TCF3 1 schmitzBurkittLymphomaPathogenesis2012 22885699 GOF 22885699 schmitzBurkittLymphomaPathogenesis2012 abateDistinctViralMutational2015
29 TCL1A 1 TRUE grandeGenomewideDiscoverySomatic2019 30617194 thomasGeneticSubgroupsInform2023
30 TFAP4 1 grandeGenomewideDiscoverySomatic2019 30617194 LOF 34283887 toncUnexpectedSuppressionTumorigenesis2021 paneaWholeGenomeLandscape2019
31 TP53 1 wildaInactivationARFMDM2p53Pathway2004 14712292 LOF 12826609 katoUnderstandingFunctionstructureFunctionmutation2003 schmitzBurkittLymphomaPathogenesis2012
32 USP7 1 grandeGenomewideDiscoverySomatic2019 30617194 paneaWholeGenomeLandscape2019
33 WNK1 1 thomasGeneticSubgroupsInform2023 36201743 paneaWholeGenomeLandscape2019
34 IGLL5 1 TRUE PASS 4 paneaWholeGenomeLandscape2019 31558468 thomasGeneticSubgroupsInform2023
35 TBL1XR1 2 maSubtypespecificCooccurringGenetic2022 33792219
36 B2M 2 maSubtypespecificCooccurringGenetic2022 33792219
37 ADAMTS5 2 burkhardtClinicalRelevanceMolecular2022 35794096
38 ADNP 2 burkhardtClinicalRelevanceMolecular2022 35794096
39 AGO4 2 burkhardtClinicalRelevanceMolecular2022 35794096
40 ARHGEF1 2 muppidiLossSignalingGa132014 25274307
41 BCL2 2 TRUE burkhardtClinicalRelevanceMolecular2022 35794096
42 BTG1 2 TRUE burkhardtClinicalRelevanceMolecular2022 35794096
43 C16orf48 2 schmitzBurkittLymphomaPathogenesis2012 22885699
44 CARD11 2 maSubtypespecificCooccurringGenetic2022 33792219
45 CARD4 2 PASS 4 loveGeneticLandscapeMutations2012 23143597
46 CCNF 2 abateDistinctViralMutational2015 26468873
47 CD79A 2 burkhardtClinicalRelevanceMolecular2022 35794096
48 CDC27 2 maSubtypespecificCooccurringGenetic2022 33792219
49 CD83 2 TRUE PASS 3 paneaWholeGenomeLandscape2019 31558468
50 CDC73 2 PASS 3 loveGeneticLandscapeMutations2012 23143597
51 HIST1H1B 2 maSubtypespecificCooccurringGenetic2022 33792219
52 CDKN2A 2 grandeGenomewideDiscoverySomatic2019 30617194
53 CDKN2C 2 thomasGeneticSubgroupsInform2023 36201743
54 CHD4 2 burkhardtClinicalRelevanceMolecular2022 35794096
55 CPXM2 2 burkhardtClinicalRelevanceMolecular2022 35794096
56 CXCR4 2 TRUE PASS 4 paneaWholeGenomeLandscape2019 31558468
57 DHCR7 2 schmitzBurkittLymphomaPathogenesis2012 22885699
58 E2F2 2 burkhardtClinicalRelevanceMolecular2022 35794096
59 EBF1 2 TRUE thomasGeneticSubgroupsInform2023 36201743
60 EDNRB 2 burkhardtClinicalRelevanceMolecular2022 35794096
61 EHD1 2 thomasGeneticSubgroupsInform2023 36201743
62 EIF4A1 2 paneaWholeGenomeLandscape2019 31558468
63 ELP2 2 schmitzBurkittLymphomaPathogenesis2012 22885699
64 EPPK1 2 paneaWholeGenomeLandscape2019 31558468
65 ERAP1 2 burkhardtClinicalRelevanceMolecular2022 35794096
66 EXOSC6 2 schmitzBurkittLymphomaPathogenesis2012 22885699
67 FLYWCH1 2 schmitzBurkittLymphomaPathogenesis2012 22885699
68 GGTLA4 2 PASS 4 loveGeneticLandscapeMutations2012 23143597
69 GTSE1 2 schmitzBurkittLymphomaPathogenesis2012 22885699
70 HIST1H3D 2 TRUE PASS 3 paneaWholeGenomeLandscape2019 31558468
71 HIST1H3I 2 TRUE PASS 4 paneaWholeGenomeLandscape2019 31558468
72 HIST1H4J 2 TRUE PASS 3 paneaWholeGenomeLandscape2019 31558468
73 HLA-DQB1 2 burkhardtClinicalRelevanceMolecular2022 35794096
74 IKZF3 2 TRUE PASS 3 paneaWholeGenomeLandscape2019 31558468
75 IRF8 2 TRUE PASS 4 paneaWholeGenomeLandscape2019 31558468
76 KANK2 2 schmitzBurkittLymphomaPathogenesis2012 22885699
77 KLHL26 2 burkhardtClinicalRelevanceMolecular2022 35794096
78 KMT2C 2 zhouSporadicEndemicBurkitt2019 31300419
79 MCL1 2 PASS 4 paneaWholeGenomeLandscape2019 31558468
80 MIR142 2 TRUE grandeGenomewideDiscoverySomatic2019 30617194
81 MKI67 2 schmitzBurkittLymphomaPathogenesis2012 22885699
82 MYO18A 2 schmitzBurkittLymphomaPathogenesis2012 22885699
83 NBEAL1 2 PASS 4 loveGeneticLandscapeMutations2012 23143597
84 NCOR2 2 schmitzBurkittLymphomaPathogenesis2012 22885699
85 NOA1 2 burkhardtClinicalRelevanceMolecular2022 35794096
86 P2RY2 2 PASS 4 loveGeneticLandscapeMutations2012 23143597
87 PDCD11 2 schmitzBurkittLymphomaPathogenesis2012 22885699
88 PIM1 2 TRUE burkhardtClinicalRelevanceMolecular2022 35794096
89 PLCG2 2 PASS 3 paneaWholeGenomeLandscape2019 31558468
90 TNFRSF14 2 maSubtypespecificCooccurringGenetic2022 33792219
91 PPP6R2 2 burkhardtClinicalRelevanceMolecular2022 35794096
92 PREX1 2 burkhardtClinicalRelevanceMolecular2022 35794096
93 RANBP6 2 PASS 5 loveGeneticLandscapeMutations2012 23143597
94 REV3L 2 burkhardtClinicalRelevanceMolecular2022 35794096
95 RNF144B 2 PASS 3 paneaWholeGenomeLandscape2019 31558468
96 RPL10 2 burkhardtClinicalRelevanceMolecular2022 35794096
97 S1PR2 2 TRUE muppidiLossSignalingGa132014 25274307
98 SAL3 2 burkhardtClinicalRelevanceMolecular2022 35794096
99 TET2 2 thomasGeneticSubgroupsInform2023 36201743
100 TOP2A 2 schmitzBurkittLymphomaPathogenesis2012 22885699