| 1 |
31516393 |
10.1186/s12935-019-0954-3 |
2022 |
Development of transplantable B-cell lymphomas in the MHC-defined miniature swine model. |
PRKDC |
| 2 |
33615686 |
10.1002/kjm2.12352 |
2022 |
The depletion of Circ-PRKDC enhances autophagy and apoptosis in T-cell acute lymphoblastic leukemia via microRNA-653-5p/Reelin mediation of the PI3K/AKT/mTOR signaling pathway. |
PRKDC |
| 3 |
33974997 |
10.1016/j.ymthe.2021.05.006 |
2022 |
Self-driving armored CAR-T cells overcome a suppressive milieu and eradicate CD19<sup>+</sup> Raji lymphoma in preclinical models. |
PRKDC |
| 4 |
34158342 |
10.1158/1535-7163.MCT-21-0074 |
2022 |
Targeting TfR1 with the ch128.1/IgG1 Antibody Inhibits EBV-driven Lymphomagenesis in Immunosuppressed Mice Bearing EBV<sup>+</sup> Human Primary B-cells. |
PRKDC |
| 5 |
35255940 |
10.1186/s12967-022-03317-7 |
2022 |
Lenvatinib inhibits the growth of gastric cancer patient-derived xenografts generated from a heterogeneous population. |
PRKDC |
| 6 |
35400595 |
10.1016/j.jcyt.2022.02.006 |
2022 |
CCR7 expression in CD19 chimeric antigen receptor-engineered natural killer cells improves migration toward CCL19-expressing lymphoma cells and increases tumor control in mice with human lymphoma. |
PRKDC |
| 7 |
35411036 |
10.1038/s41388-022-02301-1 |
2022 |
Novel TENM3-ALK fusion is an alternate mechanism for ALK activation in neuroblastoma. |
PRKDC |
| 8 |
35659513 |
10.1016/j.canlet.2022.215762 |
2022 |
CD147-specific chimeric antigen receptor T cells effectively inhibit T cell acute lymphoblastic leukemia. |
PRKDC |
| 9 |
30546948 |
10.1080/2162402X.2018.1512455 |
2021 |
Ibrutinib significantly inhibited Bruton's tyrosine kinase (BTK) phosphorylation,<i>in-vitro</i> proliferation and enhanced overall survival in a preclinical Burkitt lymphoma (BL) model. |
PRKDC |
| 10 |
31736441 |
10.1177/0300985819882631 |
2021 |
Morphologic and Immunohistochemical Characterization of Spontaneous Lymphoma/Leukemia in NSG Mice. |
PRKDC |
| 11 |
32202225 |
10.1177/0300985820913265 |
2021 |
Spectrum of Posttransplant Lymphoproliferations in NSG Mice and Their Association With EBV Infection After Engraftment of Pediatric Solid Tumors. |
PRKDC |
| 12 |
32938796 |
10.1126/scitranslmed.aba5942 |
2021 |
B cell acute lymphoblastic leukemia cells mediate RANK-RANKL-dependent bone destruction. |
PRKDC |
| 13 |
33106625 |
10.1038/s41375-020-01068-2 |
2021 |
Xenograft and cell culture models of Sézary syndrome reveal cell of origin diversity and subclonal heterogeneity. |
PRKDC |
| 14 |
33593826 |
10.1136/jitc-2020-001524 |
2021 |
Nanoencapsulated rituximab mediates superior cellular immunity against metastatic B-cell lymphoma in a complement competent humanized mouse model. |
PRKDC |
| 15 |
30623002 |
10.1016/j.omtm.2018.11.010 |
2020 |
Development of a Novel Anti-CD19 Chimeric Antigen Receptor: A Paradigm for an Affordable CAR T Cell Production at Academic Institutions. |
PRKDC |
| 16 |
31967647 |
10.1093/jpids/piaa005 |
2020 |
A 4-Year-Old Boy With Prolonged Cough and Fever. |
PRKDC |
| 17 |
32103174 |
10.1038/s41586-020-2041-2 |
2020 |
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis. |
PRKDC |
| 18 |
29221181 |
10.18632/oncotarget.21619 |
2019 |
Analysis of CTCL cell lines reveals important differences between mycosis fungoides/Sézary syndrome <i>vs. HTLV-1<sup>+</sup></i> leukemic cell lines. |
PRKDC |
| 19 |
29702521 |
10.1097/MOH.0000000000000433 |
2019 |
DNA damage pathways and B-cell lymphomagenesis. |
PRKDC |
| 20 |
28355107 |
10.1177/0300985817698210 |
2018 |
Pathology of Aging in NOD scid gamma Female Mice. |
PRKDC |
| 21 |
28465297 |
10.1158/1541-7786.MCR-16-0305 |
2018 |
Comprehensive Transcriptome and Mutational Profiling of Endemic Burkitt Lymphoma Reveals EBV Type-Specific Differences. |
PRKDC |
| 22 |
29070697 |
10.1126/scitranslmed.aao1214 |
2018 |
Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways. |
PRKDC |
| 23 |
30159932 |
10.1111/vde.12650 |
2018 |
Phenotypic analysis of mice xenografted with canine epitheliotropic cutaneous T-cell lymphoma cells. |
PRKDC |
| 24 |
27181405 |
10.1016/j.ajpath.2016.03.012 |
2017 |
Intrahepatic Xenograft of Cutaneous T-Cell Lymphoma Cell Lines: A Useful Model for Rapid Biological and Therapeutic Evaluation. |
PRKDC |
| 25 |
27235137 |
10.1182/blood-2016-02-700328 |
2017 |
Dual TORK/DNA-PK inhibition blocks critical signaling pathways in chronic lymphocytic leukemia. |
PRKDC |
| 26 |
27373144 |
10.1016/j.dnarep.2016.06.001 |
2017 |
Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways. |
PRKDC |
| 27 |
28331319 |
10.2147/IJN.S127575 |
2017 |
Humanized CD7 nanobody-based immunotoxins exhibit promising anti-T-cell acute lymphoblastic leukemia potential. |
PRKDC |
| 28 |
28698205 |
10.1182/blood-2017-01-764316 |
2017 |
An Fc-engineered CD19 antibody eradicates MRD in patient-derived <i>MLL</i>-rearranged acute lymphoblastic leukemia xenografts. |
PRKDC |
| 29 |
25678421 |
10.1016/j.jcpa.2014.11.008 |
2016 |
Reconstruction of canine diffuse large B-cell lymphoma gene regulatory network: detection of functional modules and hub genes. |
PRKDC |
| 30 |
25868101 |
10.1097/BRS.0000000000000821 |
2016 |
Apoptosis in human compressive myelopathy due to metastatic neoplasia. |
PRKDC |
| 31 |
26446488 |
10.1038/ncomms9325 |
2016 |
LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair. |
PRKDC |
| 32 |
26546522 |
|
2016 |
Hoechst 33342 Staining Identifies the Progenitor Side Population in NOD.Cg-PrkdcscidIL2rgtmWjl/Sz Mice Harboring Pediatric Leukemias. |
PRKDC |
| 33 |
26869395 |
10.1182/blood-2015-08-665034 |
2016 |
The ability to cross the blood-cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts. |
PRKDC |
| 34 |
27489678 |
10.1177/2050313X14568698 |
2016 |
Spontaneous development of neoplasms in severe combined immunodeficient mice. |
PRKDC |
| 35 |
24586935 |
10.1371/journal.pone.0089649 |
2015 |
Ectopic TLX1 expression accelerates malignancies in mice deficient in DNA-PK. |
PRKDC |
| 36 |
24740260 |
10.1371/journal.pone.0093568 |
2015 |
The progeroid phenotype of Ku80 deficiency is dominant over DNA-PKCS deficiency. |
PRKDC |
| 37 |
24956209 |
|
2015 |
Irradiated compared with nonirradiated NSG mice for the development of a human B-cell lymphoma model. |
PRKDC |
| 38 |
25359989 |
10.1182/blood-2014-05-572743 |
2015 |
Both mature KIR+ and immature KIR- NK cells control pediatric acute B-cell precursor leukemia in NOD.Cg-Prkdcscid IL2rgtmWjl/Sz mice. |
PRKDC |
| 39 |
23232667 |
10.3892/ijo.2012.1734 |
2014 |
Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model. |
PRKDC |
| 40 |
23761041 |
10.1126/scitranslmed.3005814 |
2014 |
Therapeutic targeting of a robust non-oncogene addiction to PRKDC in ATM-defective tumors. |
PRKDC |
| 41 |
24589354 |
10.1016/j.etp.2014.01.006 |
2014 |
Histopathological characteristics of human non-tumor thyroid tissues in a long-term model of adenomatous goiter xenografts in the NOD/Shi-scid, IL-2Rγ(null) mouse. |
PRKDC |
| 42 |
24862967 |
10.1038/labinvest.2014.61 |
2014 |
Mouse models of mantle cell lymphoma, complex changes in gene expression and phenotype of engrafted MCL cells: implications for preclinical research. |
PRKDC |
| 43 |
22614020 |
10.1038/onc.2012.199 |
2013 |
PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis. |
PRKDC |
| 44 |
23022380 |
10.1016/j.molcel.2012.08.022 |
2013 |
NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function. |
PRKDC |
| 45 |
23526331 |
10.1002/ijc.28170 |
2013 |
Engraftment of low numbers of pediatric acute lymphoid and myeloid leukemias into NOD/SCID/IL2Rcγnull mice reflects individual leukemogenecity and highly correlates with clinical outcome. |
PRKDC |
| 46 |
23960188 |
10.1084/jem.20122842 |
2013 |
DNA repair genes are selectively mutated in diffuse large B cell lymphomas. |
PRKDC |
| 47 |
22529269 |
10.1084/jem.20111437 |
2012 |
Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs. |
PRKDC |
| 48 |
20629733 |
10.1111/j.1600-0625.2010.01138.x |
2011 |
A novel xenograft model of cutaneous T-cell lymphoma. |
PRKDC |
| 49 |
21512274 |
10.1538/expanim.60.181 |
2011 |
Immunodeficient NOD-scid IL-2Rγ(null) mice do not display T and B cell leakiness. |
PRKDC |
| 50 |
19773279 |
10.1136/oem.2008.044024 |
2010 |
Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. |
PRKDC |
| 51 |
20739953 |
10.1038/leu.2010.184 |
2010 |
High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias. |
PRKDC |
| 52 |
20813000 |
10.1111/j.1365-2141.2010.08364.x |
2010 |
Polymorphisms in DNA repair genes and risk of non-Hodgkin lymphoma in a pooled analysis of three studies. |
PRKDC |
| 53 |
19573080 |
10.1111/j.1365-2141.2009.07790.x |
2009 |
Common genetic variants in candidate genes and risk of familial lymphoid malignancies. |
PRKDC |
| 54 |
18507045 |
|
2008 |
18F-FDG small animal PET for early detection of human anaplastic large cells lymphoma xenograft in immunocompromised mice. |
PRKDC |
| 55 |
18688847 |
10.1002/ijc.23772 |
2008 |
Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains. |
PRKDC |
| 56 |
16000400 |
10.1093/carcin/bgi175 |
2007 |
The association of DNA-dependent protein kinase activity with chromosomal instability and risk of cancer. |
PRKDC |
| 57 |
15105825 |
10.1038/sj.embor.7400127 |
2005 |
Shorter telomeres, accelerated ageing and increased lymphoma in DNA-PKcs-deficient mice. |
PRKDC |
| 58 |
15215044 |
10.1016/j.yexmp.2004.02.001 |
2004 |
Expression of DNA-PKcs and Ku86, but not Ku70, differs between lymphoid malignancies. |
PRKDC |
| 59 |
12970738 |
10.1038/sj.onc.1206826 |
2003 |
Multiple molecular mechanisms contribute to radiation sensitivity in mantle cell lymphoma. |
PRKDC |
| 60 |
11953863 |
10.1038/sj.bjc.6600191 |
2002 |
Phosphorothioate oligonucleotides, suramin and heparin inhibit DNA-dependent protein kinase activity. |
PRKDC |
| 61 |
11160753 |
10.1128/JVI.75.5.2475-2481.2001 |
2001 |
EBNA-LP associates with cellular proteins including DNA-PK and HA95. |
PRKDC |
| 62 |
11264175 |
10.1182/blood.v97.7.2084 |
2001 |
BCR-ABL down-regulates the DNA repair protein DNA-PKcs. |
PRKDC |
| 63 |
11292837 |
10.1093/nar/29.8.1653 |
2001 |
Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells. |
PRKDC |
| 64 |
11439324 |
10.1038/sj.onc.1204497 |
2001 |
Variations in Prkdc encoding the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) and susceptibility to radiation-induced apoptosis and lymphomagenesis. |
PRKDC |
| 65 |
10395545 |
10.1016/s0960-9822(99)80311-x |
1999 |
Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient. |
PRKDC |
| 66 |
9426062 |
|
1998 |
The radiosensitive cell line 180BR is not defective in the major DNA damage-sensing proteins. |
PRKDC |
| 67 |
9657696 |
10.1021/bi980198o |
1998 |
Implication of DNA-dependent protein kinase in an early, essential, local phosphorylation event during end-joining of DNA double-strand breaks in vitro. |
PRKDC |
| 68 |
9688310 |
10.1002/(sici)1097-0215(19980831)77:5<755::aid-ijc15>3.0.co;2-0 |
1998 |
Resistance to etoposide-induced apoptosis in a Burkitt's lymphoma cell line. |
PRKDC |
| 69 |
9377575 |
|
1997 |
A DNA double-strand break defective fibroblast cell line (180BR) derived from a radiosensitive patient represents a new mutant phenotype. |
PRKDC |
| 70 |
9398855 |
10.1038/ng1297-479 |
1997 |
Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis. |
PRKDC |
| 71 |
9398856 |
10.1038/ng1297-483 |
1997 |
DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus. |
PRKDC |
| 72 |
8086496 |
10.1016/0167-4889(94)90234-8 |
1994 |
Molecular properties, substrate specificity and regulation of DNA-dependent protein kinase from Raji Burkitt's lymphoma cells. |
PRKDC |
| 73 |
1597196 |
10.1111/j.1432-1033.1992.tb16964.x |
1992 |
DNA-activated protein kinase in Raji Burkitt's lymphoma cells. Phosphorylation of c-Myc oncoprotein. |
PRKDC |
Datasets
Models
