| 1 |
35444653 |
10.3389/fimmu.2022.866582 |
2022 |
AIOLOS Variants Causing Immunodeficiency in Human and Mice. |
IKZF3 |
| 2 |
35583604 |
10.1158/1078-0432.CCR-21-3347 |
2022 |
Interactome of Aiolos/Ikaros Reveals Combination Rationale of Cereblon Modulators with HDAC Inhibitors in DLBCL. |
IKZF3 |
| 3 |
35920299 |
10.1096/fj.202200061RR |
2022 |
Mcm2 hypomorph leads to acute leukemia or hematopoietic stem cell failure, dependent on genetic context. |
IKZF3 |
| 4 |
32420699 |
10.1002/cam4.3136 |
2021 |
Serine-227 in the N-terminal kinase domain of RSK2 is a potential therapeutic target for mantle cell lymphoma. |
IKZF3 |
| 5 |
34105458 |
10.19746/j.cnki.issn.1009-2137.2021.03.006 |
2021 |
[Relationship between IKZF3 Gene Single Nucleotide Polymorphisms and Childhood Acute Lymphoblastic Leukemia]. |
IKZF3 |
| 6 |
34378936 |
10.1021/acs.jmedchem.1c00901 |
2021 |
Folate-Guided Protein Degradation by Immunomodulatory Imide Drug-Based Molecular Glues and Proteolysis Targeting Chimeras. |
IKZF3 |
| 7 |
34646650 |
10.7759/cureus.17598 |
2021 |
An Aggressive Presentation of Mantle Cell Lymphoma With Unique Molecular Features. |
IKZF3 |
| 8 |
29931583 |
10.1007/s10637-018-0623-8 |
2020 |
Dual targeting of bromodomain-containing 4 by AZD5153 and BCL2 by AZD4320 against B-cell lymphomas concomitantly overexpressing c-MYC and BCL2. |
IKZF3 |
| 9 |
30277089 |
10.1080/10428194.2018.1508669 |
2020 |
A phase 2 study of lenalidomide and dexamethasone in previously untreated patients with chronic lymphocytic leukemia (CLL). |
IKZF3 |
| 10 |
30802347 |
10.1002/anie.201901336 |
2020 |
Development of Dual and Selective Degraders of Cyclin-Dependent Kinases 4 and 6. |
IKZF3 |
| 11 |
31882553 |
10.21873/cgp.20169 |
2020 |
BRD4-Regulated Molecular Targets in Mantle Cell Lymphoma: Insights into Targeted Therapeutic Approach. |
IKZF3 |
| 12 |
32631903 |
10.1128/MCB.00189-20 |
2020 |
Janus Kinase Mutations in Mice Lacking PU.1 and Spi-B Drive B Cell Leukemia through Reactive Oxygen Species-Induced DNA Damage. |
IKZF3 |
| 13 |
32906688 |
10.3390/cancers12092541 |
2020 |
Combination Treatment with GSK126 and Pomalidomide Induces B-Cell Differentiation in <i>EZH2</i> Gain-of-Function Mutant Diffuse Large B-Cell Lymphoma. |
IKZF3 |
| 14 |
29718735 |
10.1080/10428194.2018.1466290 |
2019 |
Expression of CRBN, IKZF1, and IKZF3 does not predict lenalidomide sensitivity and mutations in the cereblon pathway are infrequent in multiple myeloma. |
IKZF3 |
| 15 |
29788898 |
10.2174/1871529X18666180522073855 |
2019 |
Treatment of Lymphoid and Myeloid Malignancies by Immunomodulatory Drugs. |
IKZF3 |
| 16 |
29954751 |
10.1182/blood-2018-01-828418 |
2019 |
CK1α and IRF4 are essential and independent effectors of immunomodulatory drugs in primary effusion lymphoma. |
IKZF3 |
| 17 |
29955133 |
10.1038/s41416-018-0153-3 |
2019 |
Integrative analysis of oncogenic fusion genes and their functional impact in colorectal cancer. |
IKZF3 |
| 18 |
30087459 |
10.1038/s41374-018-0108-6 |
2019 |
Enzyme-free digital counting of endogenous circular RNA molecules in B-cell malignancies. |
IKZF3 |
| 19 |
30545835 |
10.1182/blood-2018-07-862953 |
2019 |
Bruton tyrosine kinase degradation as a therapeutic strategy for cancer. |
IKZF3 |
| 20 |
29348612 |
10.1038/s41467-017-02596-9 |
2018 |
GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21. |
IKZF3 |
| 21 |
27070758 |
10.1016/j.leukres.2016.03.002 |
2017 |
Risk stratification of T-cell Acute Lymphoblastic Leukemia patients based on gene expression, mutations and copy number variation. |
IKZF3 |
| 22 |
27229929 |
10.1186/s12885-016-2374-2 |
2017 |
Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor. |
IKZF3 |
| 23 |
28378641 |
10.1177/1010428317695929 |
2017 |
Downregulation of PRDM1 promotes cellular invasion and lung cancer metastasis. |
IKZF3 |
| 24 |
28479318 |
10.1016/j.jid.2017.04.010 |
2017 |
Identification of Somatic Mutations in Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type by Massive Parallel Sequencing. |
IKZF3 |
| 25 |
28848064 |
10.4049/jimmunol.1700106 |
2017 |
Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4<sup>+</sup> Th Cells. |
IKZF3 |
| 26 |
25608224 |
10.3892/mmr.2015.3214 |
2016 |
Overexpression of Aiolos in Nalm-6 acute lymphoblastic leukaemia cells reduces apoptosis by suppressing phosphatase and tensin homologue deleted on chromosome 10 and activating the phosphatidylinositol-3-kinase/Akt signalling pathway. |
IKZF3 |
| 27 |
26119939 |
10.1038/onc.2015.245 |
2016 |
Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 inhibitors. |
IKZF3 |
| 28 |
26544893 |
10.18632/oncotarget.6000 |
2016 |
Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia. |
IKZF3 |
| 29 |
25524659 |
10.3892/or.2014.3677 |
2015 |
Upregulation of AIOLOS induces apoptosis and enhances etoposide chemosensitivity in Jurkat leukemia cells. |
IKZF3 |
| 30 |
26002965 |
10.1182/blood-2015-02-628669 |
2015 |
CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL. |
IKZF3 |
| 31 |
26185311 |
10.1309/AJCPW83OXPYKPEEN |
2015 |
Adult Low-Hypodiploid Acute B-Lymphoblastic Leukemia With IKZF3 Deletion and TP53 Mutation: Comparison With Pediatric Patients. |
IKZF3 |
| 32 |
23600753 |
10.1111/cas.12181 |
2014 |
Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T cell growth. |
IKZF3 |
| 33 |
24072100 |
10.1038/leu.2013.283 |
2014 |
Exome sequencing reveals novel and recurrent mutations with clinical impact in blastic plasmacytoid dendritic cell neoplasm. |
IKZF3 |
| 34 |
23022380 |
10.1016/j.molcel.2012.08.022 |
2013 |
NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function. |
IKZF3 |
| 35 |
23334668 |
10.1038/ng.2532 |
2013 |
The genomic landscape of hypodiploid acute lymphoblastic leukemia. |
IKZF3 |
| 36 |
23704093 |
10.1182/blood-2013-01-480244 |
2013 |
Runx1 is essential at two stages of early murine B-cell development. |
IKZF3 |
| 37 |
20432734 |
|
2010 |
Analysis of Ikaros family splicing variants in human hematopoietic lineages. |
IKZF3 |
| 38 |
18332232 |
10.1182/blood-2007-12-125682 |
2008 |
Aberrant Ikaros, Aiolos, and Helios expression in Hodgkin and non-Hodgkin lymphoma. |
IKZF3 |
| 39 |
17344859 |
10.1038/nature05690 |
2007 |
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. |
IKZF3 |
| 40 |
11937265 |
10.1016/s0301-472x(01)00796-2 |
2002 |
Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukemia. |
IKZF3 |
| 41 |
11173542 |
10.1111/j.1349-7006.2001.tb01045.x |
2001 |
Genetic mapping and allelic loss analysis in mouse thymic lymphomas of Helios and Aiolos belonging to the Ikaros gene family. |
IKZF3 |
| 42 |
10552935 |
10.1006/geno.1999.5949 |
2000 |
Human aiolos, an ikaros-related zinc finger DNA binding protein: cDNA cloning, tissue expression pattern, and chromosomal mapping. |
IKZF3 |
| 43 |
9806640 |
10.1016/s1074-7613(00)80637-8 |
1998 |
Aiolos regulates B cell activation and maturation to effector state. |
IKZF3 |
Datasets
Models
