| 1 |
32885355 |
10.1007/s10637-020-00996-1 |
2022 |
The anti-malaria agent artesunate exhibits cytotoxic effects in primary effusion lymphoma. |
IKBKB |
| 2 |
33640899 |
10.1038/s41392-021-00477-8 |
2022 |
TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO. |
IKBKB |
| 3 |
34114393 |
10.19852/j.cnki.jtcm.2021.03.004 |
2022 |
Dihydromyricetin promotes apoptosis, suppresses proliferation and tumor necrosis factor-α-mediated nuclear factor kappa-B activation in nasopharyngeal carcinoma CNE-2 cell. |
IKBKB |
| 4 |
35525271 |
10.1016/j.jbc.2022.102012 |
2022 |
Mechanistic insights into the activation of the IKK kinase complex by the Kaposi's sarcoma herpes virus oncoprotein vFLIP. |
IKBKB |
| 5 |
35641486 |
10.1038/s41419-022-04946-y |
2022 |
Hepatocyte Bcl-3 protects from death-receptor mediated apoptosis and subsequent acute liver failure. |
IKBKB |
| 6 |
32024820 |
10.1038/s41419-020-2294-6 |
2021 |
Reversal of CYLD phosphorylation as a novel therapeutic approach for adult T-cell leukemia/lymphoma (ATLL). |
IKBKB |
| 7 |
32473470 |
10.1016/j.cellimm.2020.104129 |
2021 |
Gain-of-function mutations in CARD11 promote enhanced aggregation and idiosyncratic signalosome assembly. |
IKBKB |
| 8 |
32627230 |
10.1002/jat.4003 |
2021 |
Cantharidin-induced acute hepatotoxicity: the role of TNF-α, IKK-α, Bcl-2, Bax and caspase3. |
IKBKB |
| 9 |
32682634 |
10.1016/j.jdermsci.2020.06.013 |
2021 |
Hydroa vacciniforme-like lymphoproliferative disorder: A study of clinicopathology and whole-exome sequencing in Chinese patients. |
IKBKB |
| 10 |
32858764 |
10.1111/jcmm.15774 |
2021 |
IKKε and TBK1 in diffuse large B-cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF-κB and IL-10 signalling. |
IKBKB |
| 11 |
32961552 |
10.1182/blood.2020007507 |
2021 |
Mutational landscape of gray zone lymphoma. |
IKBKB |
| 12 |
33098696 |
10.1111/ejh.13540 |
2021 |
RLTPR Q575E: A novel recurrent gain-of-function mutation in patients with adult T-cell leukemia/lymphoma. |
IKBKB |
| 13 |
33176636 |
10.2174/0929867327666201111142307 |
2021 |
A Critical Transcription Factor NF-κB as a Cancer Therapeutic Target and its Inhibitors as Cancer Treatment Options. |
IKBKB |
| 14 |
34132431 |
10.1002/ptr.7157 |
2021 |
Suppression of phosphoinositide 3-kinase/phosphoinositide-dependent kinase-1/serum and glucocorticoid-induced protein kinase pathway. |
IKBKB |
| 15 |
34474146 |
10.1016/j.exphem.2021.08.010 |
2021 |
miRNA-223-3p modulates ibrutinib resistance through regulation of the CHUK/Nf-κb signaling pathway in mantle cell lymphoma. |
IKBKB |
| 16 |
34521919 |
10.1038/s41598-021-97775-6 |
2021 |
KCTD15 deregulation is associated with alterations of the NF-κB signaling in both pathological and physiological model systems. |
IKBKB |
| 17 |
30688264 |
10.4103/1673-5374.249226 |
2020 |
<i>Shuxuetong</i> injection protects cerebral microvascular endothelial cells against oxygen-glucose deprivation reperfusion. |
IKBKB |
| 18 |
31324389 |
10.1016/j.prp.2019.152528 |
2020 |
Quantitative proteomics analysis of differentially expressed proteins in activated B-cell-like diffuse large B-cell lymphoma using quantitative proteomics. |
IKBKB |
| 19 |
31497245 |
10.18632/oncotarget.27098 |
2020 |
Proliferative, pro-inflammatory, and angiogenesis regulator gene expression profile defines prognosis in different histopathological subtypes of nodal peripheral T-cell lymphoma. |
IKBKB |
| 20 |
31606621 |
10.1016/j.biopha.2019.109530 |
2020 |
Investigation of candidate molecular biomarkers for expression profile analysis of the Gene expression omnibus (GEO) in acute lymphocytic leukemia (ALL). |
IKBKB |
| 21 |
32019925 |
10.1038/s41467-020-14502-x |
2020 |
A central role of IKK2 and TPL2 in JNK activation and viral B-cell transformation. |
IKBKB |
| 22 |
32286300 |
10.1038/s41467-020-15576-3 |
2020 |
Modulation of virus-induced NF-κB signaling by NEMO coiled coil mimics. |
IKBKB |
| 23 |
29295643 |
10.1080/10428194.2017.1413186 |
2019 |
The genomic landscape of two Burkitt lymphoma cases and derived cell lines: comparison between primary and relapse samples. |
IKBKB |
| 24 |
29367645 |
10.1038/s41419-017-0157-6 |
2019 |
CD40L mediated alternative NFκB-signaling induces resistance to BCR-inhibitors in patients with mantle cell lymphoma. |
IKBKB |
| 25 |
30199532 |
10.1371/journal.pbio.2006347 |
2019 |
Transcriptional outcomes and kinetic patterning of gene expression in response to NF-κB activation. |
IKBKB |
| 26 |
30335863 |
10.1371/journal.pone.0206014 |
2019 |
Oncogenic mutations in IKKβ function through global changes induced by K63-linked ubiquitination and result in autocrine stimulation. |
IKBKB |
| 27 |
27840321 |
10.1016/j.freeradbiomed.2016.11.010 |
2018 |
Pro-apoptotic effects of lipid oxidation products: HNE at the crossroads of NF-κB pathway and anti-apoptotic Bcl-2. |
IKBKB |
| 28 |
28587181 |
10.3390/nu9060561 |
2018 |
Chronic Inflammatory Diseases and Green Tea Polyphenols. |
IKBKB |
| 29 |
28906487 |
10.1038/cddis.2017.442 |
2018 |
Identification of 11(13)-dehydroivaxillin as a potent therapeutic agent against non-Hodgkin's lymphoma. |
IKBKB |
| 30 |
29194363 |
10.3390/ijms18122581 |
2018 |
The E3 Ubiquitin Ligase RNF7 Negatively Regulates CARD14/CARMA2sh Signaling. |
IKBKB |
| 31 |
29333957 |
10.1177/1533034617745761 |
2018 |
MiR-98 Promotes Apoptosis of Glioma Cells via Suppressing IKBKE/NF-κB Pathway. |
IKBKB |
| 32 |
29649481 |
10.1016/j.bbrc.2018.04.057 |
2018 |
Role of IκB kinase β in regulating the remodeling of the CARMA1-Bcl10-MALT1 complex. |
IKBKB |
| 33 |
29665857 |
10.1186/s12977-018-0415-4 |
2018 |
The HTLV-1 oncoprotein Tax is modified by the ubiquitin related modifier 1 (Urm1). |
IKBKB |
| 34 |
30111412 |
10.7534/j.issn.1009-2137.2018.04.024 |
2018 |
[Effect of IKK2 Inhibitor LY2409881 on Diffuse Large B-Cell Lymphoma Cell Apoptosis and Its Mechanism]. |
IKBKB |
| 35 |
27123832 |
10.1016/j.leukres.2016.04.012 |
2017 |
Identification of TBK1 and IKKε, the non-canonical IκB kinases, as crucial pro-survival factors in HTLV-1-transformed T lymphocytes. |
IKBKB |
| 36 |
27681433 |
10.1016/j.celrep.2016.08.080 |
2017 |
MALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage. |
IKBKB |
| 37 |
28689659 |
10.1016/j.molcel.2017.06.011 |
2017 |
Bcl3 Phosphorylation by Akt, Erk2, and IKK Is Required for Its Transcriptional Activity. |
IKBKB |
| 38 |
28931678 |
10.1128/JVI.01170-17 |
2017 |
IKKγ-Mimetic Peptides Block the Resistance to Apoptosis Associated with Kaposi's Sarcoma-Associated Herpesvirus Infection. |
IKBKB |
| 39 |
25748427 |
10.1371/journal.pone.0119363 |
2016 |
MALT1-ubiquitination triggers non-genomic NF-κB/IKK signaling upon platelet activation. |
IKBKB |
| 40 |
26158216 |
10.18632/oncotarget.4106 |
2016 |
Neutrophils trigger a NF-κB dependent polarization of tumor-supportive stromal cells in germinal center B-cell lymphomas. |
IKBKB |
| 41 |
26209362 |
10.1016/j.ejphar.2015.07.046 |
2016 |
A natural xanthone increases catalase activity but decreases NF-kappa B and lipid peroxidation in U-937 and HepG2 cell lines. |
IKBKB |
| 42 |
26247921 |
10.1002/jcp.25122 |
2016 |
Nuclear Translocation of p65 is Controlled by Sec6 via the Degradation of IκBα. |
IKBKB |
| 43 |
26275874 |
10.1007/82_2015_479 |
2016 |
Roles of the NF-κB Pathway in B-Lymphocyte Biology. |
IKBKB |
| 44 |
26525107 |
10.1038/ncomms9777 |
2016 |
The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling. |
IKBKB |
| 45 |
26573110 |
10.3892/ijo.2015.3238 |
2016 |
Involvement of cyclic-nucleotide response element-binding family members in the radiation response of Ramos B lymphoma cells. |
IKBKB |
| 46 |
26603838 |
10.1182/blood-2015-07-658781 |
2016 |
Active IKKβ promotes the stability of GLI1 oncogene in diffuse large B-cell lymphoma. |
IKBKB |
| 47 |
26647777 |
10.3892/ijo.2015.3247 |
2016 |
Diallyl trisulfide induces apoptosis by suppressing NF-κB signaling through destabilization of TRAF6 in primary effusion lymphoma. |
IKBKB |
| 48 |
26740240 |
10.1038/srep18934 |
2016 |
Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction. |
IKBKB |
| 49 |
26988706 |
10.1186/s13073-016-0280-5 |
2016 |
A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses. |
IKBKB |
| 50 |
27070702 |
10.1016/j.ccell.2016.03.006 |
2016 |
Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma. |
IKBKB |
| 51 |
24362528 |
10.1038/onc.2013.552 |
2015 |
HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains. |
IKBKB |
| 52 |
24732096 |
10.4161/cc.28707 |
2015 |
BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response. |
IKBKB |
| 53 |
24798348 |
10.1371/journal.pone.0095404 |
2015 |
A phase I clinical trial of systemically delivered NEMO binding domain peptide in dogs with spontaneous activated B-cell like diffuse large B-cell lymphoma. |
IKBKB |
| 54 |
24867235 |
10.1038/ncomms4898 |
2015 |
Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKε- and CYLD-dependent Bcl3 activation. |
IKBKB |
| 55 |
25096806 |
10.3892/ijo.2014.2578 |
2015 |
Protein kinase C-associated kinase regulates NF-κB activation through inducing IKK activation. |
IKBKB |
| 56 |
25187543 |
10.1128/JVI.01766-14 |
2015 |
Activation of NF-κB by the Kaposi's sarcoma-associated herpesvirus K15 protein involves recruitment of the NF-κB-inducing kinase, IκB kinases, and phosphorylation of p65. |
IKBKB |
| 57 |
25245034 |
10.1186/s12964-014-0049-7 |
2015 |
AIP augments CARMA1-BCL10-MALT1 complex formation to facilitate NF-κB signaling upon T cell activation. |
IKBKB |
| 58 |
25280822 |
10.1016/j.jstrokecerebrovasdis.2014.05.032 |
2015 |
Anti-inflammatory and antiapoptotic effects of mesenchymal stem cells transplantation in rat brain with cerebral ischemia. |
IKBKB |
| 59 |
25304104 |
10.1016/j.yexcr.2014.09.034 |
2015 |
Withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-κB signaling. |
IKBKB |
| 60 |
25355930 |
10.1158/1078-0432.CCR-14-0384 |
2015 |
The novel IKK2 inhibitor LY2409881 potently synergizes with histone deacetylase inhibitors in preclinical models of lymphoma through the downregulation of NF-κB. |
IKBKB |
| 61 |
25446254 |
10.1016/j.cellsig.2014.11.014 |
2015 |
TRAIL activates JNK and NF-κB through RIP1-dependent and -independent pathways. |
IKBKB |
| 62 |
25736755 |
10.1007/978-1-4939-2422-6_16 |
2015 |
Elucidating dynamic protein-protein interactions and ubiquitination in NF-κB signaling pathways. |
IKBKB |
| 63 |
25987724 |
10.1084/jem.20142009 |
2015 |
Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia. |
IKBKB |
| 64 |
26116531 |
10.1016/j.bbrc.2015.06.120 |
2015 |
Niclosamide, an anti-helminthic molecule, downregulates the retroviral oncoprotein Tax and pro-survival Bcl-2 proteins in HTLV-1-transformed T lymphocytes. |
IKBKB |
| 65 |
23620411 |
10.1158/1078-0432.CCR-12-3258 |
2014 |
Japonicone A suppresses growth of Burkitt lymphoma cells through its effect on NF-κB. |
IKBKB |
| 66 |
23886693 |
10.1016/j.imbio.2013.06.013 |
2014 |
Activation of NF-κB and respiratory burst following Aspergillus fumigatus stimulation of macrophages. |
IKBKB |
| 67 |
23963361 |
10.1158/1535-7163.MCT-13-0239 |
2014 |
Novel treatment for mantle cell lymphoma including therapy-resistant tumor by NF-κB and mTOR dual-targeting approach. |
IKBKB |
| 68 |
24239354 |
10.1016/j.celrep.2013.10.022 |
2014 |
Context-specific BAFF-R signaling by the NF-κB and PI3K pathways. |
IKBKB |
| 69 |
24303085 |
10.1371/journal.pone.0082688 |
2014 |
Lupeol is one of active components in the extract of Chrysanthemum indicum Linne that inhibits LMP1-induced NF-κB activation. |
IKBKB |
| 70 |
24352466 |
10.1128/JVI.03025-13 |
2014 |
Human T-cell leukemia virus type 1 Tax-deregulated autophagy pathway and c-FLIP expression contribute to resistance against death receptor-mediated apoptosis. |
IKBKB |
| 71 |
24464015 |
10.1182/blood-2014-01-547943 |
2014 |
IKK-dependent activation of NF-κB contributes to myeloid and lymphoid leukemogenesis by BCR-ABL1. |
IKBKB |
| 72 |
24825920 |
10.1126/scisignal.2004882 |
2014 |
T cell receptor signals to NF-κB are transmitted by a cytosolic p62-Bcl10-Malt1-IKK signalosome. |
IKBKB |
| 73 |
25049379 |
10.1073/pnas.1411701111 |
2014 |
Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors. |
IKBKB |
| 74 |
25107905 |
10.1074/jbc.M114.598763 |
2014 |
IκB kinase β (IKBKB) mutations in lymphomas that constitutively activate canonical nuclear factor κB (NFκB) signaling. |
IKBKB |
| 75 |
22595758 |
10.1038/cdd.2012.54 |
2013 |
PIDDosome-independent tumor suppression by Caspase-2. |
IKBKB |
| 76 |
22653339 |
10.1038/cdd.2012.67 |
2013 |
C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in β-cells. |
IKBKB |
| 77 |
22653966 |
10.1158/1535-7163.MCT-12-0141 |
2013 |
Oxidative stress induced by curcumin promotes the death of cutaneous T-cell lymphoma (HuT-78) by disrupting the function of several molecular targets. |
IKBKB |
| 78 |
22889356 |
10.3109/10428194.2012.720371 |
2013 |
Norcantharidin enhances bortezomib-antimyeloma activity in multiple myeloma cells in vitro and in nude mouse xenografts. |
IKBKB |
| 79 |
23028875 |
10.1371/journal.pone.0045244 |
2013 |
Distinct motifs in the intracellular domain of human CD30 differentially activate canonical and alternative transcription factor NF-κB signaling. |
IKBKB |
| 80 |
23032187 |
10.1038/emboj.2012.241 |
2013 |
Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation. |
IKBKB |
| 81 |
23087406 |
10.4049/jimmunol.1102952 |
2013 |
Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells. |
IKBKB |
| 82 |
23149938 |
10.1128/MCB.00850-12 |
2013 |
A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH domains that induce Bcl10 ubiquitination and human lymphoma cell survival. |
IKBKB |
| 83 |
23278479 |
10.1111/imm.12035 |
2013 |
The combination of IκB kinase β inhibitor and everolimus modulates expression of interleukin-10 in human T-cell lymphotropic virus type-1-infected T cells. |
IKBKB |
| 84 |
23463379 |
10.1002/ijc.28148 |
2013 |
Ca2+/calmodulin-dependent kinase II contributes to inhibitor of nuclear factor-kappa B kinase complex activation in Helicobacter pylori infection. |
IKBKB |
| 85 |
23632891 |
10.1182/blood-2012-12-470153 |
2013 |
Trimeric G protein-CARMA1 axis links smoothened, the hedgehog receptor transducer, to NF-κB activation in diffuse large B-cell lymphoma. |
IKBKB |
| 86 |
23727036 |
10.1016/j.jaci.2013.04.047 |
2013 |
A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency. |
IKBKB |
| 87 |
21375523 |
10.1111/j.1365-2141.2011.08591.x |
2012 |
Bortezomib interacts synergistically with belinostat in human acute myeloid leukaemia and acute lymphoblastic leukaemia cells in association with perturbations in NF-κB and Bim. |
IKBKB |
| 88 |
21881048 |
10.1182/blood-2011-06-359166 |
2012 |
Alteration of BIRC3 and multiple other NF-κB pathway genes in splenic marginal zone lymphoma. |
IKBKB |
| 89 |
21951590 |
10.1111/j.1349-7006.2011.02110.x |
2012 |
An IκB kinase 2 inhibitor IMD-0354 suppresses the survival of adult T-cell leukemia cells. |
IKBKB |
| 90 |
21987722 |
10.1158/0008-5472.CAN-11-1715 |
2012 |
IKKβ and NF-κB transcription govern lymphoma cell survival through AKT-induced plasma membrane trafficking of GLUT1. |
IKBKB |
| 91 |
22099304 |
10.1016/j.molcel.2011.09.015 |
2012 |
Direct, noncatalytic mechanism of IKK inhibition by A20. |
IKBKB |
| 92 |
22262057 |
10.1002/jcp.24057 |
2012 |
Inactivation of Bcl-2 through IκB kinase (IKK)-dependent phosphorylation mediates apoptosis upon exposure to 4-hydroxynonenal (HNE). |
IKBKB |
| 93 |
22343828 |
10.1038/cmi.2011.59 |
2012 |
Regulation of NF-κB signaling by the A20 deubiquitinase. |
IKBKB |
| 94 |
22361669 |
10.4161/auto.8.2.18763 |
2012 |
Autophagy prolongs survival after NFκB inhibition in B-cell lymphomas. |
IKBKB |
| 95 |
22384180 |
10.1371/journal.pone.0032215 |
2012 |
Arsenic trioxide exerts antimyeloma effects by inhibiting activity in the cytoplasmic substrates of histone deacetylase 6. |
IKBKB |
| 96 |
22435562 |
10.1111/j.1600-065X.2012.01094.x |
2012 |
Dynamic roles for NF-κB in HTLV-I and HIV-1 retroviral pathogenesis. |
IKBKB |
| 97 |
22474286 |
10.1074/jbc.M111.291708 |
2012 |
Forkhead transcription factor FOXO3a protein activates nuclear factor κB through B-cell lymphoma/leukemia 10 (BCL10) protein and promotes tumor cell survival in serum deprivation. |
IKBKB |
| 98 |
22713244 |
10.4161/cc.20859 |
2012 |
Activity of the selective IκB kinase inhibitor BMS-345541 against T-cell acute lymphoblastic leukemia: involvement of FOXO3a. |
IKBKB |
| 99 |
22715589 |
10.3727/096504012x13285365944292 |
2012 |
Targeted repression of overexpressed CD30 downregulates NF-kappaB and ERK1/2 pathway in Hodgkin lymphoma cell lines. |
IKBKB |
| 100 |
22865346 |
10.1007/s13238-012-2047-0 |
2012 |
New insight into the oncogenic mechanism of the retroviral oncoprotein Tax. |
IKBKB |
Datasets
Models
