| 1 |
29707316 |
10.21037/jtd.2018.02.31 |
2022 |
Single nucleotide polymorphisms of casitas B-lineage lymphoma proto-oncogene-b predict outcomes of patients with advanced non-small cell lung cancer after first-line platinum based doublet chemotherapy. |
CBLB |
| 2 |
32158232 |
10.2147/OTT.S224866 |
2022 |
Effects of Atypical Protein Kinase C Inhibitor (DNDA) on Lung Cancer Proliferation and Migration by PKC-ι/FAK Ubiquitination Through the Cbl-b Pathway. |
CBLB |
| 3 |
33882749 |
10.1177/24725552211000675 |
2022 |
In Vitro Ubiquitination Platform Identifies Methyl Ellipticiniums as Ubiquitin Ligase Inhibitors. |
CBLB |
| 4 |
34272310 |
10.1136/jitc-2021-002889 |
2022 |
Tumor rejection in <i>Cblb</i> <sup>-/-</sup> mice depends on IL-9 and Th9 cells. |
CBLB |
| 5 |
34836490 |
10.1080/15548627.2021.1997053 |
2022 |
HYPK coordinates degradation of polyneddylated proteins by autophagy. |
CBLB |
| 6 |
35181779 |
10.1158/2326-6066.CIR-20-0973 |
2022 |
Overproduction of IFNγ by Cbl-b-Deficient CD8+ T Cells Provides Resistance against Regulatory T Cells and Induces Potent Antitumor Immunity. |
CBLB |
| 7 |
35288194 |
10.1016/j.ejphar.2022.174876 |
2022 |
Cbl-b modulated TrkA ubiquitination and function in the dorsal root ganglion of mice. |
CBLB |
| 8 |
35733270 |
10.1073/pnas.2201490119 |
2022 |
IFT80 negatively regulates osteoclast differentiation via association with Cbl-b to disrupt TRAF6 stabilization and activation. |
CBLB |
| 9 |
27371568 |
10.1074/jbc.A113.529925 |
2021 |
Myostatin induces insulin resistance via Casitas B-lineage lymphoma b (Cblb)-mediated degradation of insulin receptor substrate 1 (IRS1) in response to high calorie diet intake. |
CBLB |
| 10 |
31663116 |
10.1002/jcp.29338 |
2021 |
miR-22-3p enhances the intrinsic regenerative abilities of primary sensory neurons via the CBL/p-EGFR/p-STAT3/GAP43/p-GAP43 axis. |
CBLB |
| 11 |
32373983 |
10.26355/eurrev_202004_21027 |
2021 |
The effect of Casitas b-lineage lymphoma b on regulating T follicular helper in lupus nephritis. |
CBLB |
| 12 |
33625672 |
10.1007/s12094-021-02569-x |
2021 |
Hypoxia-mediated down-regulation of miRNAs' biogenesis promotes tumor immune escape in bladder cancer. |
CBLB |
| 13 |
33741730 |
10.1136/jitc-2020-001975 |
2021 |
<i>CBLB</i> ablation with CRISPR/Cas9 enhances cytotoxicity of human placental stem cell-derived NK cells for cancer immunotherapy. |
CBLB |
| 14 |
33848699 |
10.1016/j.bmc.2021.116130 |
2021 |
An affinity prediction approach for the ligand of E3 ligase Cbl-b and an insight into substrate binding pattern. |
CBLB |
| 15 |
34038132 |
10.1021/acs.jnatprod.1c00367 |
2021 |
Sinularamides A-G, Terpenoid-Derived Spermidine and Spermine Conjugates with Casitas B-Lineage Lymphoma Proto-Oncogene B (Cbl-b) Inhibitory Activities from a <i>Sinularia</i> sp. Soft Coral. |
CBLB |
| 16 |
34048740 |
10.1016/j.ejphar.2021.174205 |
2021 |
BDNF modulated KCC2 ubiquitylation in spinal cord dorsal horn of mice. |
CBLB |
| 17 |
34535769 |
10.1038/s41388-021-02012-z |
2021 |
Identification of mutations that cooperate with defects in B cell transcription factors to initiate leukemia. |
CBLB |
| 18 |
27446403 |
10.3892/ol.2016.4730 |
2020 |
Cbl-b promotes cell detachment via ubiquitination of focal adhesion kinase. |
CBLB |
| 19 |
30442330 |
10.1016/j.cellimm.2018.11.002 |
2020 |
Regulation of immune responses by E3 ubiquitin ligase Cbl-b. |
CBLB |
| 20 |
30452556 |
10.1093/eurheartj/ehy714 |
2020 |
Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death. |
CBLB |
| 21 |
31056398 |
10.1016/j.ccell.2019.03.014 |
2020 |
Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality. |
CBLB |
| 22 |
31531847 |
10.1002/eji.201948204 |
2020 |
TAM receptors attenuate murine NK-cell responses via E3 ubiquitin ligase Cbl-b. |
CBLB |
| 23 |
31790392 |
10.1371/journal.pbio.3000554 |
2020 |
Dynamic trafficking and turnover of JAM-C is essential for endothelial cell migration. |
CBLB |
| 24 |
32154175 |
10.3389/fonc.2020.00181 |
2020 |
miR-1323 Promotes Cell Migration in Lung Adenocarcinoma by Targeting Cbl-b and Is an Early Prognostic Biomarker. |
CBLB |
| 25 |
29205205 |
10.1038/tpj.2017.41 |
2019 |
Gene expression and linkage analysis implicate CBLB as a mediator of rituximab resistance. |
CBLB |
| 26 |
29513566 |
10.1152/ajpcell.00184.2017 |
2019 |
Reactive oxygen species upregulate expression of muscle atrophy-associated ubiquitin ligase Cbl-b in rat L6 skeletal muscle cells. |
CBLB |
| 27 |
29729186 |
10.1002/hep.30073 |
2019 |
CD2-Associated Protein Contributes to Hepatitis C, Virus Propagation and Steatosis by Disrupting Insulin Signaling. |
CBLB |
| 28 |
29938552 |
10.1177/0300060518770955 |
2019 |
Isoflurane decreases interleukin-2 production by increasing c-Cbl and Cbl-b expression in rat peripheral blood mononuclear cells. |
CBLB |
| 29 |
30021515 |
10.1186/s12871-018-0555-z |
2019 |
Increased expression of the Cbl family of E3 ubiquitin ligases decreases Interleukin-2 production in a rat model of peripheral neuropathy. |
CBLB |
| 30 |
30024968 |
10.1371/journal.ppat.1007111 |
2019 |
Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB. |
CBLB |
| 31 |
30402490 |
10.1155/2018/6728128 |
2019 |
Gene Expression Profile Signature of Aggressive Waldenström Macroglobulinemia with Chromosome 6q Deletion. |
CBLB |
| 32 |
28970470 |
10.1038/s41467-017-00830-y |
2018 |
NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia. |
CBLB |
| 33 |
28972304 |
10.1002/1878-0261.12140 |
2018 |
DR5-Cbl-b/c-Cbl-TRAF2 complex inhibits TRAIL-induced apoptosis by promoting TRAF2-mediated polyubiquitination of caspase-8 in gastric cancer cells. |
CBLB |
| 34 |
25351606 |
10.1111/1756-185X.12509 |
2017 |
Dysregulation of anergy-related factors involved in regulatory T cells defects in Systemic Lupus Erythematosus patients: Rapamycin and Vitamin D efficacy in restoring regulatory T cells. |
CBLB |
| 35 |
26732495 |
10.1016/j.cllc.2015.11.008 |
2017 |
Single Nucleotide Polymorphisms in CBLB, a Regulator of T-Cell Response, Predict Radiation Pneumonitis and Outcomes After Definitive Radiotherapy for Non-Small-Cell Lung Cancer. |
CBLB |
| 36 |
27039262 |
10.1016/j.jid.2016.03.024 |
2017 |
Identification of Gene Mutations and Fusion Genes in Patients with Sézary Syndrome. |
CBLB |
| 37 |
27432944 |
10.1084/jem.20151932 |
2017 |
E3 ubiquitin ligase Cbl-b negatively regulates C-type lectin receptor-mediated antifungal innate immunity. |
CBLB |
| 38 |
27685907 |
|
2017 |
Cbl-b regulates the sensitivity of cetuximab through ubiquitin-proteasome system in human gastric cancer cells. |
CBLB |
| 39 |
28100467 |
10.1242/dev.138164 |
2017 |
An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance. |
CBLB |
| 40 |
28940360 |
10.1111/cei.13054 |
2017 |
Lys63-polyubiquitination by the E3 ligase casitas B-lineage lymphoma-b (Cbl-b) modulates peripheral regulatory T cell tolerance in patients with systemic lupus erythematosus. |
CBLB |
| 41 |
25952305 |
10.1002/humu.22809 |
2016 |
Molecular Diversity and Associated Phenotypic Spectrum of Germline CBL Mutations. |
CBLB |
| 42 |
26087197 |
10.18632/oncotarget.4382 |
2016 |
The E3 ubiquitin ligase Cbl-b improves the prognosis of RANK positive breast cancer patients by inhibiting RANKL-induced cell migration and metastasis. |
CBLB |
| 43 |
26342078 |
10.1074/jbc.M115.661413 |
2016 |
Pro-oncogenic Roles of HLXB9 Protein in Insulinoma Cells through Interaction with Nono Protein and Down-regulation of the c-Met Inhibitor Cblb (Casitas B-lineage Lymphoma b). |
CBLB |
| 44 |
26416283 |
10.4049/jimmunol.1501200 |
2016 |
Protein Tyrosine Phosphatase SHP-1 Modulates T Cell Responses by Controlling Cbl-b Degradation. |
CBLB |
| 45 |
26583948 |
10.1164/rccm.201502-0250OC |
2016 |
Small Molecule T315 Promotes Casitas B-Lineage Lymphoma-Dependent Degradation of Epidermal Growth Factor Receptor via Y1045 Autophosphorylation. |
CBLB |
| 46 |
24614797 |
10.1507/endocrj.ej14-0048 |
2015 |
Ubiquitin ligase Cbl-b and obesity-induced insulin resistance. |
CBLB |
| 47 |
24632608 |
10.1038/onc.2014.22 |
2015 |
MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy. |
CBLB |
| 48 |
24875217 |
10.4161/cc.29213 |
2015 |
E3 ubiquitin ligase Cbl-b in innate and adaptive immunity. |
CBLB |
| 49 |
25261476 |
10.4049/jimmunol.1303077 |
2015 |
A multiple sclerosis-associated variant of CBLB links genetic risk with type I IFN function. |
CBLB |
| 50 |
25285640 |
10.1016/j.bbrc.2014.09.125 |
2015 |
Cbl regulates the activity of SIRT2. |
CBLB |
| 51 |
25691332 |
10.1111/febs.13238 |
2015 |
Ionizing radiation-inducible miR-30e promotes glioma cell invasion through EGFR stabilization by directly targeting CBL-B. |
CBLB |
| 52 |
25701378 |
10.1007/s13277-015-3232-6 |
2015 |
Celecoxib sensitizes gastric cancer to rapamycin via inhibition of the Cbl-b-regulated PI3K/Akt pathway. |
CBLB |
| 53 |
25829233 |
10.1016/j.clim.2015.03.018 |
2015 |
Cbl-b-deficient mice express alterations in trafficking-related molecules but retain sensitivity to the multiple sclerosis therapeutic agent, FTY720. |
CBLB |
| 54 |
25891013 |
10.1002/art.39163 |
2015 |
The anergy induction of M3 muscarinic acetylcholine receptor-reactive CD4+ T cells suppresses experimental sialadenitis-like Sjögren's syndrome. |
CBLB |
| 55 |
26112603 |
10.1016/j.febslet.2015.06.015 |
2015 |
E3 ubiquitin ligase Cbl-b suppresses human ORMDL3 expression through STAT6 mediation. |
CBLB |
| 56 |
24161672 |
10.1016/j.febslet.2013.10.007 |
2014 |
Lipid raft-regulated IGF-1R activation antagonizes TRAIL-induced apoptosis in gastric cancer cells. |
CBLB |
| 57 |
24229686 |
|
2014 |
Cbl-b and PI3K/Akt pathway are differently involved in oxygen-glucose deprivation preconditioning in PC12 cells. |
CBLB |
| 58 |
24451368 |
10.1074/jbc.M113.529925 |
2014 |
Myostatin induces insulin resistance via Casitas B-lineage lymphoma b (Cblb)-mediated degradation of insulin receptor substrate 1 (IRS1) protein in response to high calorie diet intake. |
CBLB |
| 59 |
24553136 |
10.1038/nature12998 |
2014 |
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells. |
CBLB |
| 60 |
24651487 |
10.1371/journal.pone.0089792 |
2014 |
Recruitment of Cbl-b to B cell antigen receptor couples antigen recognition to Toll-like receptor 9 activation in late endosomes. |
CBLB |
| 61 |
22456178 |
10.1016/j.ejca.2012.03.005 |
2013 |
TRAIL-activated EGFR by Cbl-b-regulated EGFR redistribution in lipid rafts antagonises TRAIL-induced apoptosis in gastric cancer cells. |
CBLB |
| 62 |
23280105 |
10.1002/art.37833 |
2013 |
Casitas B lineage lymphoma b is a key regulator of peripheral tolerance in systemic lupus erythematosus. |
CBLB |
| 63 |
23349502 |
10.2337/db12-0677 |
2013 |
Cbl-b is a critical regulator of macrophage activation associated with obesity-induced insulin resistance in mice. |
CBLB |
| 64 |
23663663 |
10.1111/febs.12333 |
2013 |
Multimeric and differential binding of CIN85/CD2AP with two atypical proline-rich sequences from CD2 and Cbl-b*. |
CBLB |
| 65 |
23684068 |
10.1016/j.jaci.2013.03.046 |
2013 |
T-cell receptor ligation causes Wiskott-Aldrich syndrome protein degradation and F-actin assembly downregulation. |
CBLB |
| 66 |
23749633 |
10.4049/jimmunol.1202068 |
2013 |
T cell activation threshold regulated by E3 ubiquitin ligase Cbl-b determines fate of inducible regulatory T cells. |
CBLB |
| 67 |
22072526 |
10.1002/gcc.20949 |
2012 |
Casitas B lymphoma mutations in childhood acute lymphoblastic leukemia. |
CBLB |
| 68 |
22884570 |
10.1016/j.febslet.2012.07.067 |
2012 |
Cbl-b-dependent degradation of FLIP(L) is involved in ATO-induced autophagy in leukemic K562 and gastric cancer cells. |
CBLB |
| 69 |
20038312 |
|
2011 |
[Expression of c-Cbl, Cbl-b, and epidermal growth factor receptor in gastric carcinoma and their clinical significance]. |
CBLB |
| 70 |
21248250 |
10.4049/jimmunol.1003390 |
2011 |
Essential role of E3 ubiquitin ligase activity in Cbl-b-regulated T cell functions. |
CBLB |
| 71 |
21645455 |
10.3779/j.issn.1009-3419.2011.06.17 |
2011 |
[Expressions of c-Cbl, Cbl-b and EGFR and its role of prognosis in NSCLC]. |
CBLB |
| 72 |
20668237 |
10.1073/pnas.1009209107 |
2010 |
T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency. |
CBLB |
| 73 |
20805496 |
10.1073/pnas.1007575107 |
2010 |
Rapidly fatal myeloproliferative disorders in mice with deletion of Casitas B-cell lymphoma (Cbl) and Cbl-b in hematopoietic stem cells. |
CBLB |
| 74 |
20890046 |
10.1172/JCI41991 |
2010 |
Abrogating Cbl-b in effector CD8(+) T cells improves the efficacy of adoptive therapy of leukemia in mice. |
CBLB |
| 75 |
19343001 |
10.1097/CAD.0b013e3283160fd6 |
2009 |
PI3K/Akt is involved in bufalin-induced apoptosis in gastric cancer cells. |
CBLB |
| 76 |
19549983 |
10.1126/scisignal.276pe38 |
2009 |
Activation of T cells: releasing the brakes by proteolytic elimination of Cbl-b. |
CBLB |
| 77 |
19549985 |
10.1126/scisignal.2000046 |
2009 |
PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradation. |
CBLB |
| 78 |
18201552 |
10.1016/j.bbrc.2008.01.032 |
2008 |
Identification and functional analysis of CBLB mutations in type 1 diabetes. |
CBLB |
| 79 |
18227156 |
10.1128/MCB.01505-07 |
2008 |
T-cell receptor-induced NF-kappaB activation is negatively regulated by E3 ubiquitin ligase Cbl-b. |
CBLB |
| 80 |
18832689 |
10.4049/jimmunol.181.8.5331 |
2008 |
Casitas B-lineage lymphoma b inhibits antigen recognition and slows cell cycle progression at late times during CD4+ T cell clonal expansion. |
CBLB |
| 81 |
17038529 |
10.1182/blood-2006-03-011759 |
2007 |
ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells. |
CBLB |
| 82 |
17259398 |
10.2337/db06-1027 |
2007 |
Genetic reconstitution of autoimmune type 1 diabetes with two major susceptibility genes in the rat. |
CBLB |
| 83 |
17364027 |
10.1172/JCI29472 |
2007 |
Ablation of Cbl-b provides protection against transplanted and spontaneous tumors. |
CBLB |
| 84 |
17391982 |
10.1016/j.smim.2007.02.004 |
2007 |
Regulation of peripheral T cell tolerance by the E3 ubiquitin ligase Cbl-b. |
CBLB |
| 85 |
17403934 |
10.1084/jem.20061699 |
2007 |
Spontaneous tumor rejection by cbl-b-deficient CD8+ T cells. |
CBLB |
| 86 |
17878343 |
10.4049/jimmunol.179.7.4473 |
2007 |
Negative regulation of CD40-mediated B cell responses by E3 ubiquitin ligase Casitas-B-lineage lymphoma protein-B. |
CBLB |
| 87 |
17045823 |
10.1016/j.immuni.2006.08.021 |
2006 |
Establishment of the major compatibility complex-dependent development of CD4+ and CD8+ T cells by the Cbl family proteins. |
CBLB |
| 88 |
15629882 |
10.1189/jlb.0904524 |
2005 |
CBLB variants in type 1 diabetes and their genetic interaction with CTLA4. |
CBLB |
| 89 |
15661906 |
10.4049/jimmunol.174.3.1472 |
2005 |
Differential control of CD28-regulated in vivo immunity by the E3 ligase Cbl-b. |
CBLB |
| 90 |
15897618 |
10.1538/expanim.54.111 |
2005 |
Identification of a major gene responsible for type 1 diabetes in the Komeda diabetes-prone rat. |
CBLB |
| 91 |
11591765 |
10.4049/jimmunol.167.8.4405 |
2001 |
CXCR3 expression on CD34(+) hemopoietic progenitors induced by granulocyte-macrophage colony-stimulating factor: II. Signaling pathways involved. |
CBLB |
Datasets
Models
