| 1 |
35301414 |
10.1038/s41379-022-01022-w |
2022 |
Nodal cytotoxic peripheral T-cell lymphoma occurs frequently in the clinical setting of immunodysregulation and is associated with recurrent epigenetic alterations. |
VAV1 |
| 2 |
35326399 |
10.3390/cells11060949 |
2022 |
Vav1 Promotes B-Cell Lymphoma Development. |
VAV1 |
| 3 |
35443168 |
10.1016/j.celrep.2022.110695 |
2022 |
Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma. |
VAV1 |
| 4 |
35895495 |
10.1002/1878-0261.13295 |
2022 |
Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model. |
VAV1 |
| 5 |
35954378 |
10.3390/cancers14153716 |
2022 |
Mutations Affecting Genes in the Proximal T-Cell Receptor Signaling Pathway in Peripheral T-Cell Lymphoma. |
VAV1 |
| 6 |
32606318 |
10.1038/s41375-020-0937-3 |
2021 |
PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis. |
VAV1 |
| 7 |
34147695 |
10.1016/j.jmoldx.2021.04.013 |
2021 |
Detection of Gene Fusion Transcripts in Peripheral T-Cell Lymphoma Using a Multiplexed Targeted Sequencing Assay. |
VAV1 |
| 8 |
34258755 |
10.1111/bjh.17639 |
2021 |
Characteristics of genetic alterations of peripheral T-cell lymphoma in childhood including identification of novel fusion genes: the Japan Children's Cancer Group (JCCG). |
VAV1 |
| 9 |
34417435 |
10.1038/s41392-021-00730-0 |
2021 |
BCL9 regulates CD226 and CD96 checkpoints in CD8<sup>+</sup> T cells to improve PD-1 response in cancer. |
VAV1 |
| 10 |
34617326 |
10.15252/embj.2021108125 |
2021 |
Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis. |
VAV1 |
| 11 |
29313423 |
10.1080/21541248.2018.1423851 |
2020 |
Rho guanosine nucleotide exchange factors are not such bad guys after all in cancer<sup>a</sup>. |
VAV1 |
| 12 |
31859368 |
10.1002/path.5376 |
2020 |
Angioimmunoblastic T-cell lymphoma contains multiple clonal T-cell populations derived from a common TET2 mutant progenitor cell. |
VAV1 |
| 13 |
32107212 |
10.1158/0008-5472.CAN-19-2787 |
2020 |
Dasatinib Is an Effective Treatment for Angioimmunoblastic T-cell Lymphoma. |
VAV1 |
| 14 |
32992343 |
10.1182/blood.2020006513 |
2020 |
VAV1 mutations contribute to development of T-cell neoplasms in mice. |
VAV1 |
| 15 |
27898263 |
10.1080/21541248.2016.1263718 |
2019 |
Genetic alterations affecting GTPases and T-cell receptor signaling in peripheral T-cell lymphomas. |
VAV1 |
| 16 |
30833082 |
10.1016/j.bbrc.2019.02.108 |
2019 |
The interaction between Vav1 and EBNA1 promotes survival of Burkitt's lymphoma cells by down-regulating the expression of Bim. |
VAV1 |
| 17 |
28832024 |
10.1038/leu.2017.273 |
2018 |
Activation of RHOA-VAV1 signaling in angioimmunoblastic T-cell lymphoma. |
VAV1 |
| 18 |
29200404 |
10.1172/JCI94509 |
2018 |
STAT5BN642H is a driver mutation for T cell neoplasia. |
VAV1 |
| 19 |
29682742 |
10.1111/eci.12939 |
2018 |
Rac-GTPases and Rac-GEFs in neutrophil adhesion, migration and recruitment. |
VAV1 |
| 20 |
30250888 |
10.1080/23723556.2018.1432257 |
2018 |
An unexpected tumor suppressor role for VAV1<sup>a</sup>. |
VAV1 |
| 21 |
28062691 |
10.1073/pnas.1608839114 |
2017 |
Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas. |
VAV1 |
| 22 |
28627735 |
10.1111/cas.13303 |
2017 |
Genetic alterations in adult T-cell leukemia/lymphoma. |
VAV1 |
| 23 |
28694326 |
10.1182/blood-2017-02-768234 |
2017 |
Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E). |
VAV1 |
| 24 |
29136506 |
10.1016/j.ccell.2017.10.004 |
2017 |
A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia. |
VAV1 |
| 25 |
27169444 |
10.11406/rinketsu.57.417 |
2016 |
[Genetic landscape of adult T-cell leukemia/lymphoma]. |
VAV1 |
| 26 |
27297792 |
10.1182/blood-2016-03-707141 |
2016 |
Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma. |
VAV1 |
| 27 |
27669408 |
10.1371/journal.pone.0163011 |
2016 |
Sensitivity Analysis of the NPM-ALK Signalling Network Reveals Important Pathways for Anaplastic Large Cell Lymphoma Combination Therapy. |
VAV1 |
| 28 |
26338970 |
10.18632/oncotarget.5009 |
2015 |
Stat5-deficient hematopoiesis is permissive for Myc-induced B-cell leukemogenesis. |
VAV1 |
| 29 |
26437031 |
10.1038/ng.3415 |
2015 |
Integrated molecular analysis of adult T cell leukemia/lymphoma. |
VAV1 |
| 30 |
24501217 |
10.1182/blood-2013-08-523563 |
2014 |
Tiam1/Rac1 signals contribute to the proliferation and chemoresistance, but not motility, of chronic lymphocytic leukemia cells. |
VAV1 |
| 31 |
24534189 |
10.1084/jem.20131424 |
2014 |
Consequences of the recurrent MYD88(L265P) somatic mutation for B cell tolerance. |
VAV1 |
| 32 |
23757206 |
10.1016/j.bmc.2013.05.021 |
2013 |
RNA-aptamers that modulate the RhoGEF activity of Tiam1. |
VAV1 |
| 33 |
22432082 |
|
2012 |
Vav1 in hematologic neoplasms, a mini review. |
VAV1 |
| 34 |
22683124 |
10.1016/j.immuni.2012.03.023 |
2012 |
The adaptor SAP controls NK cell activation by regulating the enzymes Vav-1 and SHIP-1 and by enhancing conjugates with target cells. |
VAV1 |
| 35 |
22692505 |
10.1182/blood-2011-06-361709 |
2012 |
Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival. |
VAV1 |
| 36 |
22717125 |
10.1016/j.ejcb.2012.04.006 |
2012 |
Invadopodia and rolling-type motility are specific features of highly invasive p190(bcr-abl) leukemic cells. |
VAV1 |
| 37 |
23022380 |
10.1016/j.molcel.2012.08.022 |
2012 |
NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function. |
VAV1 |
| 38 |
20007546 |
10.1182/blood-2009-04-216184 |
2010 |
Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice. |
VAV1 |
| 39 |
20155735 |
10.1002/hon.935 |
2010 |
Vav-1 expression correlates with NFκB activation and CD40-mediated cell death in diffuse large B-cell lymphoma cell lines. |
VAV1 |
| 40 |
20011522 |
10.1371/journal.pone.0008229 |
2009 |
The use of knockout mice reveals a synergistic role of the Vav1 and Rasgrf2 gene deficiencies in lymphomagenesis and metastasis. |
VAV1 |
| 41 |
18227156 |
10.1128/MCB.01505-07 |
2008 |
T-cell receptor-induced NF-kappaB activation is negatively regulated by E3 ubiquitin ligase Cbl-b. |
VAV1 |
| 42 |
18974134 |
10.1158/0008-5472.CAN-08-2568 |
2008 |
The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 activation. |
VAV1 |
| 43 |
16289966 |
10.1016/j.cellsig.2005.10.001 |
2006 |
Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human B lymphoma cell surface triggers Cbl tyrosine phosphorylation, its association with p85 subunit, Crk-L and Syk and its dissociation with Vav. |
VAV1 |
| 44 |
15345594 |
10.1182/blood-2003-08-2965 |
2005 |
The adaptor protein 3BP2 associates with VAV guanine nucleotide exchange factors to regulate NFAT activation by the B-cell antigen receptor. |
VAV1 |
| 45 |
15661896 |
10.4049/jimmunol.174.3.1385 |
2005 |
Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton. |
VAV1 |
| 46 |
15661906 |
10.4049/jimmunol.174.3.1472 |
2005 |
Differential control of CD28-regulated in vivo immunity by the E3 ligase Cbl-b. |
VAV1 |
| 47 |
15964830 |
10.1128/MCB.25.13.5777-5785.2005 |
2005 |
Generation of rac3 null mutant mice: role of Rac3 in Bcr/Abl-caused lymphoblastic leukemia. |
VAV1 |
| 48 |
14630790 |
10.1182/blood-2003-07-2469 |
2004 |
VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia. |
VAV1 |
| 49 |
14673152 |
10.1128/MCB.24.1.164-171.2003 |
2004 |
CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1. |
VAV1 |
| 50 |
12848851 |
10.1046/j.0818-9641.2003.01172.x |
2003 |
Knockout B lymphoma cell lines as biochemical tools to explore multiple signalling pathways. |
VAV1 |
| 51 |
14586401 |
10.1038/sj.onc.1207048 |
2003 |
Vav-promoter regulated oncogenic fusion protein NPM-ALK in transgenic mice causes B-cell lymphomas with hyperactive Jun kinase. |
VAV1 |
| 52 |
11846804 |
10.1046/j.0014-2956.2001.02741.x |
2002 |
Transient activation of the c-Jun N-terminal kinase (JNK) activity by ligation of the tetraspan CD53 antigen in different cell types. |
VAV1 |
| 53 |
12353912 |
10.1385/MB:22:1:025 |
2002 |
Functional cloning using pFB retroviral cDNA expression libraries. |
VAV1 |
| 54 |
10232389 |
10.1016/s0165-2478(98)00142-4 |
1999 |
Apoptosis of thymic lymphoma clones by thymic epithelial cells: a putative model for 'death by neglect'. |
VAV1 |
| 55 |
9886379 |
|
1999 |
Signaling through the EBV/C3d receptor (CR2, CD21) in human B lymphocytes: activation of phosphatidylinositol 3-kinase via a CD19-independent pathway. |
VAV1 |
| 56 |
10221598 |
10.1385/ENDO:9:3:313 |
1998 |
Prolactin receptor signaling: shared components with the T-cell antigen receptor in Nb2 lymphoma cells. |
VAV1 |
| 57 |
9040011 |
10.1093/intimm/9.2.291 |
1997 |
Targets of p56(lck) activity in immature thymoblasts: stimulation of the Ras/Raf/MAPK pathway. |
VAV1 |
| 58 |
9168816 |
10.1006/excr.1997.3535 |
1997 |
Expression of the vav oncogene in somatic cell hybrids. |
VAV1 |
| 59 |
9178638 |
10.1006/cimm.1997.1102 |
1997 |
CD40-triggered protein tyrosine phosphorylation on Vav and on phosphatidylinositol 3-kinase correlates with survival of the Ramos-Burkitt lymphoma B cell line. |
VAV1 |
| 60 |
9341187 |
10.1074/jbc.272.43.27362 |
1997 |
Identification of two tyrosine phosphoproteins, pp70 and pp68, which interact with phospholipase Cgamma, Grb2, and Vav after B cell antigen receptor activation. |
VAV1 |
| 61 |
8632004 |
10.1074/jbc.271.7.3856 |
1996 |
The tyrosine phosphatase PTP1C associates with Vav, Grb2, and mSos1 in hematopoietic cells. |
VAV1 |
| 62 |
7508909 |
|
1994 |
Interferon alpha induces rapid tyrosine phosphorylation of the vav proto-oncogene product in hematopoietic cells. |
VAV1 |
| 63 |
7689723 |
|
1993 |
Selective association of the p59fyn tyrosine kinase with murine T lymphoma membrane phosphoproteins. |
VAV1 |
| 64 |
7690544 |
10.1042/bj2940339 |
1993 |
Interleukin-2 induces tyrosine phosphorylation of the vav proto-oncogene product in human T cells: lack of requirement for the tyrosine kinase lck. |
VAV1 |
Datasets
Models
