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# pmid doi year title Hugo_Symbol
1 32124692 10.2174/1389200221666200303113456 2021 Clinical Application of Thiopurine Pharmacogenomics in Pediatrics. PRPS1
2 32391636 10.1111/jcmm.15322 2021 Molecular mechanism of c-Myc and PRPS1/2 against thiopurine resistance in Burkitt's lymphoma. PRPS1
3 29541198 10.3892/ol.2018.7903 2020 High expression of PRPS1 induces an anti-apoptotic effect in B-ALL cell lines and predicts an adverse prognosis in Chinese children with B-ALL. PRPS1
4 31697823 10.1182/blood.2019002220 2020 Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia. PRPS1
5 32391957 10.1002/pbc.28306 2020 Feasibility of monitoring peripheral blood to detect emerging clones in children with acute lymphoblastic leukemia<sup>†</sup>. PRPS1
6 32694622 10.1038/s41598-020-69059-y 2020 FPGS relapse-specific mutations in relapsed childhood acute lymphoblastic leukemia. PRPS1
7 30255549 10.1111/jcmm.13907 2019 Increase of PRPP enhances chemosensitivity of PRPS1 mutant acute lymphoblastic leukemia cells to 5-Fluorouracil. PRPS1
8 28446267 10.7534/j.issn.1009-2137.2017.02.001 2018 [PRPS1 Expression in Children with Acute Leukemia and Its Clinical Significance]. PRPS1
9 29020630 10.1016/j.celrep.2017.09.052 2018 Degradation of Bcl-2 by XIAP and ARTS Promotes Apoptosis. PRPS1
10 25998402 10.1158/2159-8290.CD-RW2015-095 2016 Thiopurine Resistance in Childhood ALL Is Mediated by PRPS1 Mutations. PRPS1
11 25962120 10.1038/nm.3840 2015 Negative feedback-defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL. PRPS1
12 26046573 10.1038/nm.3876 2015 Mutant PRPS1: a new therapeutic target in relapsed acute lymphoblastic leukemia. PRPS1