| 1 |
34857887 |
10.1038/s41388-021-02126-4 |
2022 |
HMGN1 plays a significant role in CRLF2 driven Down Syndrome leukemia and provides a potential therapeutic target in this high-risk cohort. |
P2RY8 |
| 2 |
35484080 |
10.1016/j.clml.2022.03.007 |
2022 |
Clinico-hematological and Outcome Profile of Pediatric B-other-ALL and BCR::ABL1-like pre-B-ALL: An Integrated Genomic Study From North India. |
P2RY8 |
| 3 |
35537330 |
10.1016/j.cyto.2022.155896 |
2022 |
High occurrence of CRLF2 abnormalities in Mexican children with B-cell acute lymphoblastic leukemia. |
P2RY8 |
| 4 |
35912172 |
10.3389/fonc.2022.896858 |
2022 |
Recurrent Novel <i>P2RY8/IGH</i> Translocations in B-Lymphoblastic Leukemia/Lymphoma. |
P2RY8 |
| 5 |
36076986 |
10.3390/ijms23179587 |
2022 |
Characterization of Philadelphia-like Pre-B Acute Lymphoblastic Leukemia: Experiences in Mexican Pediatric Patients. |
P2RY8 |
| 6 |
33615710 |
10.1111/ijlh.13419 |
2021 |
Effects of different aberrations in the CRLF2 gene on the biological characteristics and drug sensitivities of Nalm6 cells. |
P2RY8 |
| 7 |
33707599 |
10.1038/s41598-021-85213-6 |
2021 |
Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia with kinase fusions in Taiwan. |
P2RY8 |
| 8 |
33750258 |
10.1080/0284186X.2021.1900908 |
2021 |
Genomic landscape of B-other acute lymphoblastic leukemia in an adult retrospective cohort with a focus on <i>BCR-ABL1</i>-like subtype. |
P2RY8 |
| 9 |
33781217 |
10.1186/s12885-020-07781-6 |
2021 |
Low incidence of ABL-class and JAK-STAT signaling pathway alterations in uniformly treated pediatric and adult B-cell acute lymphoblastic leukemia patients using MRD risk-directed approach - a population-based study. |
P2RY8 |
| 10 |
33812392 |
10.19746/j.cnki.issn.1009-2137.2021.02.001 |
2021 |
[Clinical Features and Prognosis of Acute Lymphoblastic Leukemia Children with P2RY8-CRLF2 Gene Rearrangement]. |
P2RY8 |
| 11 |
33890726 |
10.1002/cjp2.211 |
2021 |
CRLF2 and IKZF1 abnormalities in Mexican children with acute lymphoblastic leukemia and recurrent gene fusions: exploring surrogate markers of signaling pathways. |
P2RY8 |
| 12 |
34159401 |
10.1007/s00277-021-04574-0 |
2021 |
Hematological characteristics, cytogenetic features, and post-induction measurable residual disease in thymic stromal lymphopoietin receptor (TSLPR) overexpressed B-cell acute lymphoblastic leukemia in an Indian cohort. |
P2RY8 |
| 13 |
34732618 |
10.11406/rinketsu.62.1465 |
2021 |
[Down syndrome and acute lymphoblastic leukemia]. |
P2RY8 |
| 14 |
33113607 |
10.3760/cma.j.issn.0253-2727.2020.09.008 |
2020 |
[Diagnosis of adult Philadelphia chromosome-like acute lymphoblastic leukemia by fluorescence in situ hybridization]. |
P2RY8 |
| 15 |
30842656 |
10.1038/s41586-019-1003-z |
2019 |
S-Geranylgeranyl-L-glutathione is a ligand for human B cell-confinement receptor P2RY8. |
P2RY8 |
| 16 |
30859636 |
10.1002/gcc.22748 |
2019 |
GATA3 germline variant is associated with CRLF2 expression and predicts outcome in pediatric B-cell precursor acute lymphoblastic leukemia. |
P2RY8 |
| 17 |
29194562 |
10.1111/bjh.15056 |
2018 |
A risk score including microdeletions improves relapse prediction for standard and medium risk precursor B-cell acute lymphoblastic leukaemia in children. |
P2RY8 |
| 18 |
29407587 |
10.1016/j.leukres.2018.01.012 |
2018 |
High frequency of intermediate and poor risk copy number abnormalities in pediatric cohort of B-ALL correlate with high MRD post induction. |
P2RY8 |
| 19 |
29507076 |
10.1182/bloodadvances.2017014704 |
2018 |
Prognostic impact of kinase-activating fusions and IKZF1 deletions in pediatric high-risk B-lineage acute lymphoblastic leukemia. |
P2RY8 |
| 20 |
29786757 |
10.1007/s12185-018-2474-7 |
2018 |
Copy number abnormality of acute lymphoblastic leukemia cell lines based on their genetic subtypes. |
P2RY8 |
| 21 |
29982439 |
10.1093/gigascience/giy079 |
2018 |
Clinker: visualizing fusion genes detected in RNA-seq data. |
P2RY8 |
| 22 |
27637012 |
10.1002/gcc.22421 |
2017 |
Prognostic significance of P2RY8-CRLF2 and CRLF2 overexpression may vary across risk subgroups of childhood B-cell acute lymphoblastic leukemia. |
P2RY8 |
| 23 |
27855558 |
10.1080/10428194.2016.1219902 |
2017 |
Diagnostic evaluation of RNA sequencing for the detection of genetic abnormalities associated with Ph-like acute lymphoblastic leukemia (ALL). |
P2RY8 |
| 24 |
27899802 |
10.1038/leu.2016.365 |
2017 |
Genomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia. |
P2RY8 |
| 25 |
28033648 |
10.1002/gcc.22439 |
2017 |
Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia. |
P2RY8 |
| 26 |
28371317 |
10.1002/pbc.26539 |
2017 |
Molecular characterization of acute lymphoblastic leukemia with high CRLF2 gene expression in childhood. |
P2RY8 |
| 27 |
28395118 |
10.1002/gcc.22464 |
2017 |
ETV6/RUNX1-like acute lymphoblastic leukemia: A novel B-cell precursor leukemia subtype associated with the CD27/CD44 immunophenotype. |
P2RY8 |
| 28 |
28408464 |
10.1182/blood-2016-12-758979 |
2017 |
Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group. |
P2RY8 |
| 29 |
28866095 |
10.1016/j.canlet.2017.08.034 |
2017 |
Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesions. |
P2RY8 |
| 30 |
29140408 |
10.1093/ajcp/aqx111 |
2017 |
Philadelphia Chromosome-like Mixed-Phenotype Acute Leukemia Demonstrating P2RY8-CRLF2 Fusion and JAK1 Mutation. |
P2RY8 |
| 31 |
26754556 |
10.1016/j.leukres.2015.11.018 |
2016 |
CRLF2 overexpression identifies an unfavourable subgroup of adult B-cell precursor acute lymphoblastic leukemia lacking recurrent genetic abnormalities. |
P2RY8 |
| 32 |
27161658 |
10.1016/j.jmoldx.2016.03.004 |
2016 |
Genome-Wide Single-Nucleotide Polymorphism Array Analysis Improves Prognostication of Acute Lymphoblastic Leukemia/Lymphoma. |
P2RY8 |
| 33 |
27959929 |
10.1371/journal.pmed.1002197 |
2016 |
Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study. |
P2RY8 |
| 34 |
26018335 |
10.1111/bjh.13514 |
2015 |
The clinical impact of IKZF1 deletions in paediatric B-cell precursor acute lymphoblastic leukaemia is independent of minimal residual disease stratification in Nordic Society for Paediatric Haematology and Oncology treatment protocols used between 1992 and 2013. |
P2RY8 |
| 35 |
23911702 |
10.3324/haematol.2013.090225 |
2014 |
High CD45 surface expression determines relapse risk in children with precursor B-cell and T-cell acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol. |
P2RY8 |
| 36 |
24935070 |
10.1002/gcc.22190 |
2014 |
An overall characterization of pediatric acute lymphoblastic leukemia with CRLF2 overexpression. |
P2RY8 |
| 37 |
25044358 |
10.1002/gcc.22201 |
2014 |
Gene alterations involving the CRLF2-JAK pathway and recurrent gene deletions in Down syndrome-associated acute lymphoblastic leukemia in Japan. |
P2RY8 |
| 38 |
25105841 |
10.1038/ncomms5654 |
2014 |
Frequent cases of RAS-mutated Down syndrome acute lymphoblastic leukaemia lack JAK2 mutations. |
P2RY8 |
| 39 |
25274307 |
10.1038/nature13765 |
2014 |
Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma. |
P2RY8 |
| 40 |
22875627 |
10.3324/haematol.2011.056135 |
2013 |
IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol. |
P2RY8 |
| 41 |
23145900 |
10.1111/bjh.12130 |
2013 |
No prognostic impact of P2RY8-CRLF2 fusion in intermediate cytogenetic risk childhood B-cell acute lymphoblastic leukaemia. |
P2RY8 |
| 42 |
23212523 |
10.1182/blood-2012-04-422691 |
2013 |
Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project. |
P2RY8 |
| 43 |
23930217 |
10.1002/cam4.87 |
2013 |
IKZF1 deletion is associated with a poor outcome in pediatric B-cell precursor acute lymphoblastic leukemia in Japan. |
P2RY8 |
| 44 |
22072402 |
10.1002/gcc.20944 |
2012 |
High frequency of BTG1 deletions in acute lymphoblastic leukemia in children with down syndrome. |
P2RY8 |
| 45 |
22343534 |
10.1073/pnas.1121343109 |
2012 |
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing. |
P2RY8 |
| 46 |
22368272 |
10.1182/blood-2011-11-394221 |
2012 |
Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study. |
P2RY8 |
| 47 |
22484421 |
10.1038/leu.2012.101 |
2012 |
Poor prognosis for P2RY8-CRLF2 fusion but not for CRLF2 over-expression in children with intermediate risk B-cell precursor acute lymphoblastic leukemia. |
P2RY8 |
| 48 |
22816614 |
10.1111/j.1365-2141.2012.09221.x |
2012 |
Treatment outcome of CRLF2-rearranged childhood acute lymphoblastic leukaemia: a comparative analysis of the AIEOP-BFM and UK NCRI-CCLG study groups. |
P2RY8 |
| 49 |
22851563 |
10.1200/JCO.2011.40.3907 |
2012 |
IGH@ translocations, CRLF2 deregulation, and microdeletions in adolescents and adults with acute lymphoblastic leukemia. |
P2RY8 |
| 50 |
23091296 |
10.1182/blood-2012-07-443218 |
2012 |
Small sizes and indolent evolutionary dynamics challenge the potential role of P2RY8-CRLF2-harboring clones as main relapse-driving force in childhood ALL. |
P2RY8 |
| 51 |
21106984 |
10.1182/blood-2010-07-297135 |
2011 |
Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial. |
P2RY8 |
| 52 |
21527530 |
10.1182/blood-2011-01-329961 |
2011 |
Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia. |
P2RY8 |
| 53 |
19965641 |
10.1182/blood-2009-08-235408 |
2010 |
Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group. |
P2RY8 |
| 54 |
20139093 |
10.1182/blood-2009-09-245944 |
2010 |
Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia. |
P2RY8 |
| 55 |
20378752 |
10.1182/blood-2009-11-256131 |
2010 |
Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol. |
P2RY8 |
| 56 |
20847213 |
10.1182/blood-2010-05-286492 |
2010 |
t(X;14)(p22;q32)/t(Y;14)(p11;q32) CRLF2-IGH translocations from human B-lineage ALLs involve CpG-type breaks at CRLF2, but CRLF2/P2RY8 intrachromosomal deletions do not. |
P2RY8 |
| 57 |
19838194 |
10.1038/ng.469 |
2009 |
Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia. |
P2RY8 |
| 58 |
17487742 |
10.1080/10428190701225882 |
2007 |
Transforming activity of purinergic receptor P2Y, G protein coupled, 8 revealed by retroviral expression screening. |
P2RY8 |
| 59 |
17554380 |
10.1038/sj.leu.2404784 |
2007 |
Upregulation of the SOX5 by promoter swapping with the P2RY8 gene in primary splenic follicular lymphoma. |
P2RY8 |
Datasets
Models
