| 1 |
28840016 |
10.21037/jtd.2017.06.20 |
2022 |
Lung adenocarcinoma: from molecular basis to genome-guided therapy and immunotherapy. |
NF1 |
| 2 |
33730843 |
10.3324/haematol.2020.269431 |
2022 |
Clinical significance of RAS pathway alterations in pediatric acute myeloid leukemia. |
NF1 |
| 3 |
34308104 |
10.1093/jncics/pkab007 |
2022 |
Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in the Childhood Cancer Survivor Study. |
NF1 |
| 4 |
34339711 |
10.1016/j.brainres.2021.147594 |
2022 |
Role of the parental NF1 carrier in effects of pharmacological inhibition of anaplastic lymphoma kinase in Neurofibromatosis 1 mutant mice. |
NF1 |
| 5 |
34995897 |
10.1016/j.cancergen.2021.12.005 |
2022 |
A complex KMT2A::AFF3 fusion resulting from a three-way chromosomal rearrangement in pediatric B lymphoblastic leukemia. |
NF1 |
| 6 |
35077772 |
10.1016/j.bbr.2022.113767 |
2022 |
Long-term effects of pharmacological inhibition of anaplastic lymphoma kinase in neurofibromatosis 1 mutant mice. |
NF1 |
| 7 |
35098592 |
10.1111/jdv.17974 |
2022 |
Identification of three clinical neurofibromatosis 1 subtypes: Latent class analysis of a series of 1351 patients. |
NF1 |
| 8 |
35363510 |
10.1200/JCO.21.02840 |
2022 |
Phase II Study of Selumetinib in Children and Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Genetic Alterations: Arm E of the NCI-COG Pediatric MATCH Trial. |
NF1 |
| 9 |
35373885 |
10.1002/pbc.29575 |
2022 |
Retrospective and integrative analyses of molecular characteristics and their specific imaging parameters in pediatric grade 1 gliomas. |
NF1 |
| 10 |
35515133 |
10.3389/fonc.2022.851572 |
2022 |
Case Report: Precision Medicine Target Revealed by <i>In Vitro</i> Modeling of Relapsed, Refractory Acute Lymphoblastic Leukemia From a Child With Neurofibromatosis. |
NF1 |
| 11 |
35689207 |
10.1186/s12943-022-01583-z |
2022 |
Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells. |
NF1 |
| 12 |
35749292 |
10.1148/rg.210235 |
2022 |
Neurofibromatosis from Head to Toe: What the Radiologist Needs to Know. |
NF1 |
| 13 |
35777330 |
10.1016/j.anndiagpath.2022.151997 |
2022 |
VEGF and VEGFR family members are expressed by neoplastic cells of NF1-associated tumors and may play an oncogenic role in malignant peripheral nerve sheath tumor growth through an autocrine loop. |
NF1 |
| 14 |
35870258 |
10.1016/j.lungcan.2022.07.011 |
2022 |
Genetic correlation of crizotinib efficacy and resistance in ALK- rearranged non-small-cell lung cancer. |
NF1 |
| 15 |
35920299 |
10.1096/fj.202200061RR |
2022 |
Mcm2 hypomorph leads to acute leukemia or hematopoietic stem cell failure, dependent on genetic context. |
NF1 |
| 16 |
31439678 |
10.3324/haematol.2019.230375 |
2021 |
Genomic profiling of primary histiocytic sarcoma reveals two molecular subgroups. |
NF1 |
| 17 |
32366782 |
10.1097/MPH.0000000000001811 |
2021 |
Coincidental Expression of Classic Hodgkin Lymphoma and Neurofibromatosis Type I and Literature Review. |
NF1 |
| 18 |
32925410 |
10.1097/MPH.0000000000001936 |
2021 |
Further Lessons Learned From a Child With NF1 and Classical Hodgkin Lymphoma. |
NF1 |
| 19 |
32929178 |
10.1038/s41379-020-00673-x |
2021 |
The mutational landscape of histiocytic sarcoma associated with lymphoid malignancy. |
NF1 |
| 20 |
33211573 |
10.2214/AJR.19.22283 |
2021 |
Imaging Features of Neurofibromatosis Type 1 in the Abdomen and Pelvis. |
NF1 |
| 21 |
33395032 |
10.1097/CCO.0000000000000711 |
2021 |
MEK inhibitors in RASopathies. |
NF1 |
| 22 |
33669386 |
10.3390/ijms22041954 |
2021 |
Spontaneous and Engineered Large Animal Models of Neurofibromatosis Type 1. |
NF1 |
| 23 |
33750258 |
10.1080/0284186X.2021.1900908 |
2021 |
Genomic landscape of B-other acute lymphoblastic leukemia in an adult retrospective cohort with a focus on <i>BCR-ABL1</i>-like subtype. |
NF1 |
| 24 |
34011343 |
10.1186/s13023-021-01856-8 |
2021 |
Lymphoproliferative malignancies in patients with neurofibromatosis 1. |
NF1 |
| 25 |
34944796 |
10.3390/cancers13246174 |
2021 |
RNA Sequencing of Primary Cutaneous and Breast-Implant Associated Anaplastic Large Cell Lymphomas Reveals Infrequent Fusion Transcripts and Upregulation of PI3K/AKT Signaling via Neurotrophin Pathway Genes. |
NF1 |
| 26 |
28413392 |
10.1159/000456029 |
2020 |
T-Cell Lymphoma in a Patient with Neurofibromatosis Type 1 and AIDS. |
NF1 |
| 27 |
28487787 |
10.1155/2017/5083463 |
2020 |
EBV-Negative Monomorphic B-Cell Posttransplant Lymphoproliferative Disorder with Marked Morphologic Pleomorphism and Pathogenic Mutations in <i>ASXL1</i>, <i>BCOR</i>, <i>CDKN2A</i>, <i>NF1</i>, and <i>TP53</i>. |
NF1 |
| 28 |
30774551 |
10.4103/wjnm.WJNM_11_18 |
2020 |
Can we differentiate malignant peripheral nerve sheath tumor from benign neurofibroma without invasive sampling. |
NF1 |
| 29 |
30946933 |
10.1016/j.humpath.2019.03.004 |
2020 |
The repertoire of genetic alterations in salivary duct carcinoma including a novel HNRNPH3-ALK rearrangement. |
NF1 |
| 30 |
31240424 |
10.1007/s10689-019-00138-4 |
2020 |
Multiple primary malignancies associated with a germline SMARCB1 pathogenic variant. |
NF1 |
| 31 |
31257073 |
10.1016/j.ccell.2019.05.015 |
2020 |
RAC1<sup>P29S</sup> Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance. |
NF1 |
| 32 |
31261022 |
10.1016/j.leukres.2019.106177 |
2020 |
High resolution Chromosomal Microarray Analysis (CMA) enhances the genetic profile of pediatric B-cell Acute Lymphoblastic Leukemia patients. |
NF1 |
| 33 |
31693904 |
10.1016/j.celrep.2019.09.071 |
2020 |
Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design. |
NF1 |
| 34 |
32104235 |
10.3892/etm.2020.8418 |
2020 |
MicroRNA-103a-3p potentiates chemoresistance to cisplatin in non-small cell lung carcinoma by targeting neurofibromatosis 1. |
NF1 |
| 35 |
29354122 |
10.3389/fimmu.2017.01901 |
2019 |
Neurofibromin 1 Impairs Natural Killer T-Cell-Dependent Antitumor Immunity against a T-Cell Lymphoma. |
NF1 |
| 36 |
29636358 |
10.1158/1078-0432.CCR-17-2452 |
2019 |
Resistance Mechanisms to Targeted Therapies in <i>ROS1</i><sup>+</sup> and <i>ALK</i><sup>+</sup> Non-small Cell Lung Cancer. |
NF1 |
| 37 |
29846633 |
10.1210/jc.2017-01845 |
2019 |
Methodology, Criteria, and Characterization of Patient-Matched Thyroid Cell Lines and Patient-Derived Tumor Xenografts. |
NF1 |
| 38 |
30280491 |
10.1002/pbc.27496 |
2019 |
Clinical and biological relevance of genetic alterations in pediatric T-cell acute lymphoblastic leukemia in Taiwan. |
NF1 |
| 39 |
30322862 |
10.1158/0008-5472.CAN-18-1867 |
2019 |
Lorlatinib Treatment Elicits Multiple On- and Off-Target Mechanisms of Resistance in ALK-Driven Cancer. |
NF1 |
| 40 |
27102345 |
10.1038/modpathol.2016.79 |
2018 |
Comprehensive genomic profiling of orbital and ocular adnexal lymphomas identifies frequent alterations in MYD88 and chromatin modifiers: new routes to targeted therapies. |
NF1 |
| 41 |
28318056 |
10.1111/pde.13094 |
2018 |
Cutaneous and Systemic Findings in Mosaic Neurofibromatosis Type 1. |
NF1 |
| 42 |
29179212 |
10.1159/000485415 |
2018 |
LukS-PV-Regulated MicroRNA-125a-3p Promotes THP-1 Macrophages Differentiation and Apoptosis by Down-Regulating NF1 and Bcl-2. |
NF1 |
| 43 |
29184034 |
10.1126/scisignal.aam7550 |
2018 |
MEK inhibitor trametinib does not prevent the growth of anaplastic lymphoma kinase (ALK)-addicted neuroblastomas. |
NF1 |
| 44 |
27174491 |
10.1038/leu.2016.83 |
2017 |
MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia. |
NF1 |
| 45 |
27181063 |
10.1016/j.exphem.2016.04.011 |
2017 |
Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B-lymphoblastic leukemia. |
NF1 |
| 46 |
27565932 |
10.1016/j.lungcan.2016.07.002 |
2017 |
Drastic initial response and subsequent response to two ALK inhibitors in a patient with a highly aggressive ALK-rearranged inflammatory myofibroblastic tumor arising in the pleural cavity. |
NF1 |
| 47 |
27628603 |
|
2017 |
Primary Effusion Lymphoma-like Lymphoma in a Patient with Neurofibromatosis Type 1. |
NF1 |
| 48 |
27659822 |
10.1007/s00381-016-3163-6 |
2017 |
An integrative molecular and genomic analysis of pediatric hemispheric low-grade gliomas: an update. |
NF1 |
| 49 |
27696251 |
10.1007/s12020-016-1080-9 |
2017 |
Targeted next-generation sequencing for TP53, RAS, BRAF, ALK and NF1 mutations in anaplastic thyroid cancer. |
NF1 |
| 50 |
27976555 |
10.24953/turkjped.2016.02.005 |
2017 |
Are the methylenetetrahydrofolate reductase 1298 and 677 gene polymorphisms related to optic glioma and hamartoma risk in neurofibromatosis type 1 patients? |
NF1 |
| 51 |
27997540 |
10.1371/journal.pmed.1002200 |
2017 |
IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study. |
NF1 |
| 52 |
28057529 |
10.1016/j.bbr.2017.01.003 |
2017 |
Genetic inhibition of Anaplastic Lymphoma Kinase rescues cognitive impairments in Neurofibromatosis 1 mutant mice. |
NF1 |
| 53 |
28408464 |
10.1182/blood-2016-12-758979 |
2017 |
Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group. |
NF1 |
| 54 |
28474981 |
10.3171/2017.2.PEDS16497 |
2017 |
Pediatric meningiomas: 65-year experience at a single institution. |
NF1 |
| 55 |
28629962 |
10.1016/j.bbr.2017.06.024 |
2017 |
Pharmacological inhibition of Anaplastic Lymphoma Kinase rescues spatial memory impairments in Neurofibromatosis 1 mutant mice. |
NF1 |
| 56 |
28694326 |
10.1182/blood-2017-02-768234 |
2017 |
Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E). |
NF1 |
| 57 |
26073032 |
10.1111/cge.12625 |
2016 |
Neurofibromatosis type 1 and malignancy in childhood. |
NF1 |
| 58 |
26432421 |
10.1002/cam4.551 |
2016 |
Whole-exome sequencing of breast cancer, malignant peripheral nerve sheath tumor and neurofibroma from a patient with neurofibromatosis type 1. |
NF1 |
| 59 |
26536237 |
10.1371/journal.pgen.1005611 |
2016 |
Anaplastic Lymphoma Kinase Acts in the Drosophila Mushroom Body to Negatively Regulate Sleep. |
NF1 |
| 60 |
27013922 |
10.2174/1389202916666151014221954 |
2016 |
Genetics of Bladder Malignant Tumors in Childhood. |
NF1 |
| 61 |
24469042 |
10.1038/onc.2013.587 |
2015 |
SPRED1, a RAS MAPK pathway inhibitor that causes Legius syndrome, is a tumour suppressor downregulated in paediatric acute myeloblastic leukaemia. |
NF1 |
| 62 |
26002977 |
10.4049/jimmunol.1402639 |
2015 |
Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia. |
NF1 |
| 63 |
24217072 |
|
2014 |
Oncologic manifestations in children with neurofibromatosis type 1 in Turkey. |
NF1 |
| 64 |
24278035 |
10.1371/journal.pgen.1003958 |
2014 |
Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency. |
NF1 |
| 65 |
24764718 |
10.3747/co.21.1803 |
2014 |
fdg-pet in two cases of neurofibromatosis type 1 and atypical malignancies. |
NF1 |
| 66 |
22294052 |
10.1007/s10072-011-0886-8 |
2013 |
Central nervous system lymphoma occurring in a patient with neurofibromatosis type 1 (von Recklinghausen disease). |
NF1 |
| 67 |
23257896 |
10.1038/bjc.2012.535 |
2013 |
Risk of benign tumours of nervous system, and of malignant neoplasms, in people with neurofibromatosis: population-based record-linkage study. |
NF1 |
| 68 |
23298878 |
10.1097/MOH.0b013e32835d82fe |
2013 |
Polycythemia vera and essential thrombocythemia: new developments in biology with therapeutic implications. |
NF1 |
| 69 |
23508829 |
10.1002/gcc.22054 |
2013 |
Next-generation-sequencing-based risk stratification and identification of new genes involved in structural and sequence variations in near haploid lymphoblastic leukemia. |
NF1 |
| 70 |
23603912 |
10.1182/blood-2012-11-465138 |
2013 |
Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations. |
NF1 |
| 71 |
20435627 |
10.3324/haematol.2009.011114 |
2012 |
Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia. |
NF1 |
| 72 |
21949657 |
10.1371/journal.pgen.1002281 |
2012 |
The receptor tyrosine kinase Alk controls neurofibromin functions in Drosophila growth and learning. |
NF1 |
| 73 |
22146869 |
10.1007/s00256-011-1333-x |
2012 |
Whole-body MRI in neurofibromatosis: incidental findings and prevalence of scoliosis. |
NF1 |
| 74 |
22514921 |
|
2012 |
[Radiation associated leukemia and myelodysplastic syndrome]. |
NF1 |
| 75 |
22675565 |
10.1371/journal.pone.0038463 |
2012 |
High accuracy mutation detection in leukemia on a selected panel of cancer genes. |
NF1 |
| 76 |
22920205 |
|
2012 |
[Constitutional mismatch repair-deficiency syndrome (CMMR-D) - a case report of a family with biallelic MSH6 mutation]. |
NF1 |
| 77 |
20065082 |
10.3324/haematol.2009.010413 |
2011 |
Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults. |
NF1 |
| 78 |
21642990 |
10.1038/ng.858 |
2011 |
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL). |
NF1 |
| 79 |
20007546 |
10.1182/blood-2009-04-216184 |
2010 |
Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice. |
NF1 |
| 80 |
20067559 |
10.1111/j.1365-2141.2009.08056.x |
2010 |
Rescue of genomic information in adult acute lymphoblastic leukaemia (ALL) with normal/failed cytogenetics: a GIMEMA centralized biological study. |
NF1 |
| 81 |
20428205 |
10.1038/leu.2010.81 |
2010 |
Pediatric early T-cell precursor leukemia with NF1 deletion and high-sensitivity in vitro to tipifarnib. |
NF1 |
| 82 |
18172006 |
10.1182/blood-2007-06-095075 |
2008 |
Leukemia-associated NF1 inactivation in patients with pediatric T-ALL and AML lacking evidence for neurofibromatosis. |
NF1 |
| 83 |
17351342 |
10.4161/cc.6.5.3919 |
2007 |
Oncogenes in myeloproliferative disorders. |
NF1 |
| 84 |
17373983 |
10.1111/j.1468-3083.2006.02013.x |
2007 |
Disseminated xanthogranulomas associated with adult T-cell leukaemia/lymphoma: a case report and review the association of haematologic malignancies. |
NF1 |
| 85 |
17440981 |
10.1002/cncr.22697 |
2007 |
Biallelic germline mutations of mismatch-repair genes: a possible cause for multiple pediatric malignancies. |
NF1 |
| 86 |
16283678 |
10.1002/ajmg.a.30998 |
2006 |
Neurofibromatosis von Recklinghausen type I phenotype and early onset of cancers in siblings compound heterozygous for mutations in MSH6. |
NF1 |
| 87 |
16341812 |
10.1007/s10689-005-8351-6 |
2006 |
Syndrome of early onset colon cancers, hematologic malignancies & features of neurofibromatosis in HNPCC families with homozygous mismatch repair gene mutations. |
NF1 |
| 88 |
16818505 |
10.1158/1535-7163.MCT-06-0012 |
2006 |
Functional analysis and molecular modeling show a preserved wild-type activity of p53(C238Y). |
NF1 |
| 89 |
15561680 |
10.1182/asheducation-2004.1.118 |
2005 |
Childhood and adolescent lymphoid and myeloid leukemia. |
NF1 |
| 90 |
15103715 |
10.1002/ajmg.a.20651 |
2004 |
Non-neurogenic sarcomas in four children and young adults with neurofibromatosis type 1. |
NF1 |
| 91 |
15255115 |
10.1076/opge.25.1.49.29005 |
2004 |
Neurofibromatosis type 1 associated with central nervous system lymphoma. |
NF1 |
| 92 |
12531231 |
10.1016/s0145-2126(02)00178-9 |
2003 |
B lineage acute lymphoblastic leukemia transformation in a child with juvenile myelomonocytic leukemia, type 1 neurofibromatosis and monosomy of chromosome 7. Possible implications in the leukemogenesis. |
NF1 |
| 93 |
12889711 |
|
2003 |
Cutaneous T-cell lymphoma in a patient with neurofibromatosis type 1. |
NF1 |
| 94 |
10979983 |
|
2000 |
Evidence that juvenile myelomonocytic leukemia can arise from a pluripotential stem cell. |
NF1 |
| 95 |
10559359 |
10.1128/JVI.73.12.10406-10415.1999 |
1999 |
Increased induction of osteopetrosis, but unaltered lymphomagenicity, by murine leukemia virus SL3-3 after mutation of a nuclear factor 1 site in the enhancer. |
NF1 |
| 96 |
9927033 |
|
1999 |
Human MLH1 deficiency predisposes to hematological malignancy and neurofibromatosis type 1. |
NF1 |
| 97 |
9796699 |
10.1038/sj.onc.1202097 |
1998 |
NF1 inactivation cooperates with N-ras in in vivo lymphogenesis activating Erk by a mechanism independent of its Ras-GTPase accelerating activity. |
NF1 |
| 98 |
8995642 |
10.1128/JVI.71.2.1196-1206.1997 |
1997 |
Second-site proviral enhancer alterations in lymphomas induced by enhancer mutants of SL3-3 murine leukemia virus: negative effect of nuclear factor 1 binding site. |
NF1 |
| 99 |
9008333 |
10.1016/s0378-1135(96)01228-x |
1997 |
Sequence analysis of the putative viral enhancer in tissues from 33 cats with various feline leukemia virus-related diseases. |
NF1 |
| 100 |
9311802 |
10.1128/JVI.71.10.7273-7280.1997 |
1997 |
Increased lymphomagenicity and restored disease specificity of AML1 site (core) mutant SL3-3 murine leukemia virus by a second-site enhancer variant evolved in vivo. |
NF1 |
Datasets
Models
