\name{methData}

\alias{methData}

\docType{data}

\title{

DNA methylation data

}

\description{

The data set includes methylation data for the 5000 most variable CpG sites of

the CLL samples. The data was produced with the use of either 450k or 850k

methylation arrays.

Preprocessing of raw IDAT files was made using minfi R/Bioconductor package

 version 1.19.16. Intensities were normalized using the functional

normalization algorithm. CpG sites containing SNPs inside the probe body 

were removed.

}

\author{Andreas Mock, Małgorzata Oleś}

\references{

Oakes CC, Seifert M, Assenov Y, Gu L, Przekopowitz M, Ruppert AS, Wang Q,

Imbusch CD, Serva A, Koser SD, et al. DNA methylation dynamics during

B cell maturation underlie a continuum of disease phenotypes in chronic

lymphocytic leukemia. Nat Genet. 2016;48(3):253-64

}

\usage{

methData

}

\format{

\code{"\linkS4class{RangedSummarizedExperiment}"} object with Features 5000 and Samples 196.

}

\keyword{datasets}